Many
of the adverse outcomes of having a traffic citation may be prevented by using a state authorized Point Reduction course course.
«Together, these findings raise the possibility that hippocampal dysfunction in GWI is one
of the adverse outcomes of persistently elevated oxidative stress and inflammation at the systemic level,» he added.
Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability
of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost
of accommodating, announced increases in the build rates
of certain aircraft; 6) the effect on aircraft demand and build rates
of changing customer preferences for business aircraft, including the effect
of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result
of global economic uncertainty or otherwise; 8) the effect
of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution
of key milestones such as the receipt
of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation
of our announced acquisition
of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability
of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk
of nonpayment by such customers; 13) any
adverse impact on Boeing's and Airbus» production
of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts
of terrorism; 14) any
adverse impact on the demand for air travel or our operations from the outbreak
of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact
of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition
of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect
of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect
of changes in tax law, such as the effect
of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations
of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect
of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability
of raw materials and purchased components; 23) our ability to recruit and retain a critical mass
of highly - skilled employees and our relationships with the unions representing many
of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment
of interest on, and principal
of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness
of any interest rate hedging programs; 28) the effectiveness
of our internal control over financial reporting; 29) the
outcome or impact
of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition
of Asco in a timely matter while avoiding any unexpected costs, charges, expenses,
adverse changes to business relationships and other business disruptions for ourselves and Asco as a result
of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks
of doing business internationally, including fluctuations in foreign current exchange rates, impositions
of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
These risks and uncertainties include, among others: the unfavorable
outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any
of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components
of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence
of efficacy and adequacy
of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results
of our clinical development activities may not be positive, or predictive
of real - world results or
of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make
adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights
of third parties, or have unintended side effects,
adverse reactions or incidents
of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.
«The complexity
of this deal and the measurement
of the
outcomes makes this event challenging and we fear disruption, in the interim, could have an
adverse impact on business,» he writes.
My conclusion is that the easing
of financial conditions resulting from non-traditional policy actions has had a material effect on both nominal and real growth and has demonstrably reduced the risk
of particularly
adverse outcomes.
We regularly assess the likelihood
of adverse outcomes resulting from these examinations to determine the adequacy
of our provision for income taxes.
Let us say that you reckon there is a 20 % chance
of an
adverse outcome; that is like saying you will be proven wrong one in every five times.
(The
outcome of the
adverse feedback.)
One must ask then how it is that if Protestant leaders in higher education generally made the right — or at least virtually inevitable — decisions, what has gone wrong that the
outcome should be so
adverse to the apparent interests
of Protestant Christianity?
«
Of the millions of animals exported under ESCAS there have been 22 identified incidents of non-compliance where the animal welfare outcome was either adverse or unknow
Of the millions
of animals exported under ESCAS there have been 22 identified incidents of non-compliance where the animal welfare outcome was either adverse or unknow
of animals exported under ESCAS there have been 22 identified incidents
of non-compliance where the animal welfare outcome was either adverse or unknow
of non-compliance where the animal welfare
outcome was either
adverse or unknown.
«The Australian beverages industry is responsive to the health and dietary requirements
of Australians but isolating any food or beverage as the sole contributor in any
adverse health
outcome overlooks many other factors that need to be considered such as health, diet and lifestyle,» the Australian Beverages Council CEO Geoff Parker said.
Mr Joyce has previously described ESCAS as making Australia «a clear world leader in the welfare
of exported live animals» due to statistics that showed from a performance report that 8,035,633 livestock were exported with just 12,958 animals — or 0.16 pc — experiencing a potentially
adverse animal welfare
outcome.
most cases
of gastroenteritis during pregnancy resolve with no
adverse outcomes on mom or baby.
Explain that if they plan birth at home there is a small increase in the risk
of an
adverse outcome for the baby.
Moreover, in out -
of - hospital settings, there is likely less antepartum testing and no continuous electronic intrapartum fetal monitoring, both
of which may have affected
adverse outcomes.
In reality, only a very small proportion
of home birth transports actually do result in such an
adverse outcome, and thus essentially have a negligible effect on hospital
outcomes.
Quote from the midwife site:» There was no evidence that planned home birth among low risk women leads to an increased risk
of severe
adverse maternal
outcomes in a maternity care system with well trained midwives and a good referral and transportation system.»
I counter: To insist the general risk pool (etc) pay for your first birth without medical resources present, in spite
of the fact that same risk pool will still be responsible for caring for any
adverse outcomes due to lack
of medical resources is hypocritical beyond belief.
Helping adolescent males to delay fatherhood may also be important from a child health perspective: research that controlled for maternal age and other key factors found teenage fatherhood associated with an increased risk
of adverse pregnancy
outcomes, including preterm birth, low birth weight and neonatal death (Chen et al, 2007).
Her research portfolio includes findings that suggest disparities in
adverse pregnancy
outcomes begin as early as conception, multivitamin use around the time
of conception prevents some miscarriages, over-the-counter use
of non-steroidal anti-inflammatory agents is not a probable cause
of miscarriage (and may be protective in some women), and the vast majority
of uterine fibroids are not associated with
adverse pregnancy
outcomes including miscarriage and preterm birth, though fibroids are related to a moderately higher likelihood
of cesarean.
Tough summarizes key research, such as the
Adverse Childhood Experience Study, a project
of the Centers for Disease Control and Kaiser Permanente, which revealed a stunning correlation between traumatic childhood events and negative adult
outcomes.
Dr. Fisher believes that dispassionate, rigorous study
of birth across all settings is more important than ever given disparities in women's access to trained and licensed care providers, current and future physician workforce issues, rising costs
of health care, and unacceptably high rates
of adverse outcomes for mothers and infants in the U.S. compared to other industrialized countries.
Ongoing projects include studies
of gene - environment interactions and
adverse pregnancy
outcomes, as well as informed medical decision making demonstration projects in Medicaid maternity populations and within HealthWise, the nation's largest source
of health information materials distributed through healthcare networks.
Women who planned a home birth were at reduced risk
of all obstetric interventions assessed and were at similar or reduced risk
of adverse maternal
outcomes compared with women who planned to give birth in hospital accompanied by a midwife or physician.
The incidence
of adverse perinatal
outcomes was low in all settings.
For healthy nulliparous women with a low risk pregnancy, the risk
of an
adverse perinatal
outcome seems to be higher for planned births at home, and the intrapartum transfer rate is high in all settings other than an obstetric unit
However, regulating it might also make it more mainstream and therefore more popular, which means the total number
of avoidable
adverse outcomes could potentially go UP.
Impact
of interpregnancy interval on the subsequent risk
of adverse perinatal
outcomes.
* If * morbidity is lower in the homebirth group because more
of those ill women died, and were thus removed from the sample, the apparent rate
of «severe
adverse maternal»
outcomes has been artificially deflated in the homebirth group — by an unknown amount — and therefore is evidence
of pretty much nothing.
For healthy women with low risk pregnancies, the incidence
of adverse perinatal
outcomes is low in all birth settings
«Women with planned home birth had lower rates
of all
adverse maternal
outcomes, albeit not significantly so for nulliparous women.»
Regulating it, using better trained practitioners and proper guidelines for risking - out and transfer definitely would reduce the rate
of adverse outcomes.
For nulliparous women, there is some evidence that planning birth at home is associated with a higher risk
of an
adverse perinatal
outcome.
There is a lack
of good quality evidence comparing the risk
of rare but serious
adverse perinatal
outcomes in these settings
There was no evidence that planned home birth among low risk women leads to an increased risk
of severe
adverse maternal
outcomes in a maternity care system with well trained midwives and a good referral and transportation system.
The strengths
of the study include the ability to compare
outcomes by the woman's planned place
of birth at the start
of care in labour, the high participation
of midwifery units and trusts in England, the large sample size and statistical power to detect clinically important differences in
adverse perinatal
outcomes, the minimisation
of selection bias through achievement
of a high response rate and absence
of self selection bias due to non-consent, the ability to compare groups that were similar in terms
of identified clinical risk (according to current clinical guidelines) and to further increase the comparability
of the groups by conducting an additional analysis restricted to women with no complicating conditions identified at the start
of care in labour, and the ability to control for several important potential confounders.
Discontinuation
of epidural analgesia late in labour for reducing the
adverse delivery
outcomes associated with epidural analgesia.
Tanaka K, Yamada H, Minami M, Kataoka S, Numazaki K, Minakami H, Tsutsumi H. «Screening for vaginal shedding
of cytomegalovirus in healthy pregnant women using real - time PCR: correlation
of CMV in the vagina and
adverse outcome of pregnancy.»
It is essential to note that these significantly increased risks
of adverse outcomes from the setting
of home and from the setting
of free - standing birth centers reported here may be serious underestimations
of clinical complications.
OF COURSE, there are going to be
adverse outcomes.
This was a systematic review
of cohort and case - control studies that compared rates
of any
adverse pregnancy
outcome (such as miscarriages, preterm delivery, intrauterine growth restriction, major congenital malformations and long - term developmental
outcomes) between women who experienced NVP and women who did not.
Tough refers the
Adverse Childhood Experiences Study, a powerful epidemiologic study showing the link between adverse early experiences and a wide range of negative health ou
Adverse Childhood Experiences Study, a powerful epidemiologic study showing the link between
adverse early experiences and a wide range of negative health ou
adverse early experiences and a wide range
of negative health
outcomes.
Regional variations in practice significantly affect rates
of interventions, near misses, and
adverse outcomes.
My midwife gave me a selection
of peer - reviewed articles about mothers on opiate medication and as she explained to me, there's no evidence that opiate use during pregnancy causes birth defects etc or long term
adverse outcomes (learning disabilities etc).
A 2014 study that examines nearly 17,000 courses
of midwife - led care confirms that among low - risk women, home births result in low rates
of interventions without an increase in
adverse outcomes for babies and mothers alike.
Secondly, some conditions mentioned in this brochure may increase the risk
of adverse pregnancy
outcomes including premature labor and delivery, birth injury, and stillbirth.
The tradeoff between the additional physical safety conferred by a hospital setting in the case
of an
adverse outcome, and the emotional comfort
of being in a familiar environment, is sufficient for her.
Literature on the links between spanking (and other types
of physical punishment) and
adverse outcomes has been conflicting.
The study reviewed the births
of nearly 17,000 women and found that, among low - risk women, planned home births result in low rates
of birth interventions without an increase in
adverse outcomes for mothers and newborns.