Imagine if you could get to the root of aging and slow the whole process down and eliminate most
of the age related diseases.
Stephen Guyenet just posted two studies showing that insulin resistance is a strong independent predictor
of age related diseases.
Numerous subsequent studies have confirmed that a calorie restriction of 30 to 60 percent of ad libitum intake increases the life span by similar amounts in a range of organisms including yeast, roundworms and rodents, while simultaneously decreasing or delaying the occurrence
of age related diseases such as numerous cancers (including lymphomas, breast and prostate cancers), hypertension, stroke, diabetes, nephropathy, autoimmune disorders and other risks factors for cardiovascular disease (3,4).
Or maybe you're just looking to get healthy and fit, to thwart the development of preventable diseases like some cancers and diabetes, or to delay the onset
of age related diseases so you can live like you're 30 or 40 well into your 70's, 80's, and even 90's!
Increasing complexity in therapeutic approaches is creating unique risks, opportunities and uncertainties in the translation of technologies for the treatment
of age related diseases.
Blueberries softens dry skin, boosts your brain, fight urinary tract infections, may even prevent cancer and lower risk
of age related diseases like Alzheimer's disease.
«We study caloric restriction because it has such a robust effect on aging and the incidence and timing
of age related disease,» says corresponding author Rozalyn Anderson, an assistant professor of geriatrics.
Data came from TwinsUK — the biggest UK adult twin registry of 12,000 twins which is used to study the genetic and environmental causes
of age related disease.
Not exact matches
«Firearm -
related deaths are the third leading cause
of death overall among U.S. children
aged 1 to 17 years, surpassing the number
of deaths from pediatric congenital anomalies, heart
disease, influenza and / or pneumonia, chronic lower respiratory
disease, and cerebrovascular causes,» wrote the CDC in its report.
And a variety
of studies are looking at what role the breakdown
of tryptophan may play in
aging and
age -
related diseases.
Venter reiterated this sentiment: «Using the combined power
of our core areas
of expertise — genomics, informatics, and stem cell therapies, we are tackling one
of the greatest medical / scientific and societal challenges —
aging and
aging related diseases,» he said in a statement.
Demographers call this reduction in the typical span
of age -
related illness «the compression
of morbidity» and attribute it primarily to improvements in the treatment
of common ailments such as heart
disease.
«Using the combined power
of our core areas
of expertise — genomics, informatics, and stem cell therapies, we are tackling one
of the greatest medical / scientific and societal challenges —
aging and
aging related diseases,» said Dr. Venter.
Using advances in genomic sequencing, the human microbiome, proteomics, informatics, computing, and cell therapy technologies, HLI is building the world's most comprehensive database
of human genotypes and phenotypes as a basis for a variety
of commercialization opportunities to help solve
aging related disease and human biological decline.
Antioxidants are substances that help to prevent the damaging effects
of oxidation in the body, and
diseases related to
aging.
The herb contains exceptionally high levels
of beta - carotene and vitamin A and is rich in zeaxanthin an anti-oxidant that helps protect
age -
related macular
disease.
Due to their bright orange skin they are an excellent source
of vitamin A that nourish the eyes and help prevent
age related macular
disease.
This type
of chronic, low level inflammation is very common and researchers believe it is a contributor in
age related diseases including cardiovascular and neurodegenerative illnesses.
Today, much
of the nutritional news on fruits and vegetables revolves around antioxidants and their role in preventing
age -
related disease.
(Studies have linked loss
of smell to the same neurotransmitters implicated in
age -
related diseases like Parkinson's and Alzheimer's.)
The herb contains exceptionally high levels
of beta - carotene and vitamin A and is rich in zeaxanthin an antioxidant that helps protect
age -
related macular
disease.
Finally, on September 30th, the New York Times reported on a telephone survey
of over 1,000 former NFL players conducted by the University
of Michigan's Institute for Social Research and commissioned by league which found, alarmingly, that former players were being diagnosed with Alzheimer's or similar memory -
related diseases at a rate 19 times higher than the normal rate for men
aged 30 through 49.
Many parents misunderstand that drooling is
related to
diseases in babies; however, it is not true.Drooling often occurs when babies are just 1 or 2 months
of age.
The Centers for
Disease Control and Prevention recommends the influenza vaccine for everyone over 6 months
of age, especially as kids under 5 years are at highest risk for complications
related to the flu.
An expert panel convened by the Institute
of Medicine clarified the cognitive
aging process by making a distinction from Alzheimer
disease and
related dementias, and provided recommendations to enhance cognitive health in older adults.
To find out, the researchers injected a cloned telomerase gene into cultured cells from retina, skin, and blood vessels, all
of which are associated with degenerative,
aging -
related diseases.
This special blend is applied to drug discovery, vaccine development, pesticide production, and the treatment
of human and veterinary infectious
diseases and
age -
related disorders.
The finding could change the course
of research into the role
of oxidation in
age -
related diseases.
«A sedentary lifestyle increases the propensity to
aging -
related disease and premature death,» researchers at King's College London report today in the journal Archives
of Internal Medicine.
Age -
related diseases include many
of the degenerative
diseases that affect billions
of people around the world and are among the leading causes
of death: cardiovascular
disease, diabetes, Alzheimer's
disease and cancer.
-- we could «identify novel drugs able to combat
age -
related diseases in completely new ways and thereby shorten the period
of chronic illness experienced at the end
of life.»
Then she moved to her current position as principal scientist
of a group that studies Alzheimer's
disease and
age -
related macular degeneration at San Francisco's Rinat Laboratories, which is owned by Pfizer.
Stem cells may also unlock some
of the doors that Alzheimer's and other
age -
related diseases close.
The work, which was done in mice, is yet more evidence
of a causal link between chromosome length and
age -
related disease.
«This truly remarkable research is worth watching,» said Gerald Weissmann, M.D., Editor - in - Chief
of The FASEB Journal, «because it may help usher in an era in which
age -
related macular degeneration is either eliminated or no longer considered a serious
disease.»
«Dementia, including the most common form Alzheimer's
Disease, and
related neurodegenerative conditions are dramatically rising in frequency as people live longer and our population
ages,» says study lead Professor Robert Richards, from the University
of Adelaide's School
of Biological Sciences.
«The next step in understanding sleep apnea in the future will be to dissect different subtypes
of sleep apnea, likely defined by distinct pathophysiological mechanisms which may underlie different outcomes and predisposition to comorbidities,» Cavadas says, «As human life expectancy increases, delaying the onset
of age -
related diseases becomes critical to our society.»
The study, published online ahead
of print in The Journal
of Clinical Investigation, has implications for treating
diseases such as diabetic retinopathy and
age -
related macular degeneration — the leading causes
of vision loss in adults.
The researchers found that, based on subjects» genetic profiles, the centenarians could be further divided into 19 subgroups, some
of which were associated with delayed onset
of age -
related diseases such as dementia, hypertension and cardiovascular
disease.
In recent years, between 71 percent and 85 percent
of flu -
related deaths have occurred among people 65 years
of age and older, according to estimates from the Centers for
Disease Control and Prevention (CDC).
People with the disorder suffer
age -
related diseases early in life, including cataracts, type 2 diabetes, hardening
of the arteries, osteoporosis and cancer, and most die in their late 40s or early 50s.
«It's fantastic news that they are going into the clinic with a cell therapy for eye
disease,» says Pete Coffey
of University College London, and head
of a team developing tiny «patches»
of RPEs for treating
age -
related macular degeneration.
Scientists have identified unique genetic signatures strongly associated with a long and healthy life, findings that could help to further the understanding
of how certain genes may offer protection from common
age -
related diseases like cancer, dementia and cardiovascular
disease.
Researchers only discovered this process in the late 1990s, but they've already begun dozens
of clinical trials to gauge whether infusing patients with these small RNAs works against a range
of diseases, from lung infections to liver cancer to
age -
related macular degeneration, a sight - stealing condition that mainly affects people over the
age of 50.
Those suffering from advanced stages
of macular degeneration may by the end
of this year be able to halt and even reverse vision loss caused by the
age -
related eye
disease.
«We think this could provide a paradigm shift in the treatment
of age -
related disease, including cancer,» said Buck professor Judith Campisi, PhD, senior scientist on the study.
The results, if confirmed, could enable doctors to better prevent those ills for which the lonely are at greater risk, such as heart
disease, infection,
age -
related dementia, and certain types
of cancer.
This trend is certainly set to stay, with an
ageing population and the emergence
of lifestyle -
related «epidemics» such as obesity, diabetes, asthma, and heart
disease.
«To improve our quality and length
of life we must delay the onset
of age -
related diseases by extending the healthiest period
of our lives.
He and Hunter teamed up with the lab
of Rusty Gage, a professor in Salk's Laboratory
of Genetics and holder
of the Vi and John Adler Chair for Research on
Age -
Related Neurodegenerative
Disease.