Sentences with phrase «of aggressive breast cancers»

As per the studies in a meta analysis, it was found that consumption of soy lowered the risk of breast cancer in women from Asian countries, it was even linked to the longer survival rates of women with certain types of aggressive breast cancers.

For this reason, the findings of this 2017 study by the University of Alabama at Birmingham could be incredibly impactful for the treatment of aggressive breast cancers.

«By understanding how stress accelerates invasion in aggressive breast tumor cells, this work will inform future studies into whether beta - blockers could be a useful adjuvant therapy in the treatment of some aggressive breast cancers.»

«Our findings suggest that this new drug combination would also help patients with this type of aggressive breast cancer as well as other cancers, such as lung, prostate and ovarian cancers,» Dr. Rassool says.

They are looking for protein indicators of aggressive breast cancer in the tissue and plasma samples.

Not exact matches

The woman asking this of her sister had been in an out of the hospital struggling with an aggressive breast cancer for three years.

Inflammatory breast cancer is a rare and aggressive form of breast cancer that occurs when malignant cells block the skin and lymph vessels of the...

Medical opinion also varies on how the kind of breast cancer Lee had, a noninvasive form called ductal carcinoma in situ, should be treated, but Lee is adamant about early mammograms and aggressive treatment.

Most of the time, he said, Watson affirms that the decisions he had already come to were correct, such as one breast cancer patient who needed aggressive chemotherapy.

«Our discovery of these mutations is a first step in developing a genetics - based system for classifying endometriosis so that clinicians can sort out which forms of the disorder may need more aggressive treatment and which may not,» says Ie - Ming Shih, M.D., Ph.D., the Richard W. TeLinde Distinguished Professor in the Department of Gynecology & Obstetrics at the Johns Hopkins University School of Medicine and co-director of the Breast and Ovarian Cancer Program at the Johns Hopkins Kimmel Cancer Center.

«This study forms the basis for future research in patients with breast cancer and offers hope for targeted therapy for patients with aggressive triple - negative inflammatory breast cancer,» said lead researcher Mateusz Opyrchal, M.D., Ph.D., Assistant Professor of Oncology at RPCI.

«We discovered that the aggressive cancer cells that are spreading in colon, breast, and skin cancer contained a much higher portion of the protein PITPNC1, than the non-aggressive cancer cells,» says researcher Nils Halberg of the CELLNET Group at the Department of Biomedicine at UiB.

Cardiff University scientists have developed a novel anti-cancer stem cell agent capable of targeting aggressive tumour forming cells common to breast, pancreas, colon and prostate cancers.

PARP inhibitors have shown efficacy for a small group of patients with breast cancer with inherited mutations in BRCA genes, but have failed in the more aggressive triple - negative disease.

A COMPOUND that slows the proliferation of triple - negative breast cancer cells in lab tests could lead to the first drugs to target this aggressive type of tumour.

Researchers in China have discovered that a metabolic enzyme called AKR1B1 drives an aggressive type of breast cancer.

Extensive studies have found that 20 % to 30 % of breast cancers are characterized by over-expression of HER2, which makes the cancer cells grow and divide faster, leading to a cancer that's more aggressive and more likely to be resistant to the standard of care.

«Our data clearly suggests that AKR1B1 overexpression represents an oncogenic event that is responsible for the aggressive behaviors of basal - like breast cancer cells,» Dong explains.

Women who have a genetic mutation face a higher risk of developing a second breast cancer and may wish to consider more aggressive treatment, preventive measures or additional screening.

Two Northwestern University scientists have identified a biomarker strongly associated with basal - like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy.

Recent studies have shown an increase in women with breast cancer choosing this more aggressive surgery, called contralateral prophylactic mastectomy, which raises the question of potential overtreatment among these patients.

Women who pursue a more aggressive surgery for early stage breast cancer have nearly eight times the odds of reporting substantial employment disruptions, according to a new study from University of Michigan Comprehensive Cancer Center researcancer have nearly eight times the odds of reporting substantial employment disruptions, according to a new study from University of Michigan Comprehensive Cancer Center researCancer Center researchers.

This included glioblastoma, the most aggressive of brain tumours, as well as lung, prostate, ovarian, breast, pancreatic and skin cancer.

The study, which will be published December 21 in the Journal of Cell Biology, suggests that the loss of these particular Numb proteins makes breast cancers more aggressive and resistant to chemotherapy, but points the way toward new therapeutic approaches that could improve patient outcome by preserving p53 levels.

The team therefore analyzed the case history of 890 breast cancer patients and found that low Numb - 1 and -2 levels correlated with an increased risk of aggressive, metastatic disease, particularly for the luminal subtype of breast cancers, which tend to retain a normal, functional copy of the p53 gene.

Scientists at Cold Spring Harbor Laboratory (CSHL) today report a discovery that they hope will lead to the development of a powerful new way of treating an aggressive form of breast cancer.

A team of researchers led by UC San Francisco scientists has identified a new drug target for triple - negative breast cancer, an aggressive disease subtype that has the poorest outcomes and accounts for as many as one in five cases.

«It's incredibly encouraging to find possible new options for patients with an aggressive cancer like triple negative breast cancer, and that studies conducted by separate teams at leading institutions agree on the implications of the findings,» said Alan Ashworth, PhD, FRS, president of UCSF Helen Diller Family Comprehensive Cancer Center, and former CEO of thcancer like triple negative breast cancer, and that studies conducted by separate teams at leading institutions agree on the implications of the findings,» said Alan Ashworth, PhD, FRS, president of UCSF Helen Diller Family Comprehensive Cancer Center, and former CEO of thcancer, and that studies conducted by separate teams at leading institutions agree on the implications of the findings,» said Alan Ashworth, PhD, FRS, president of UCSF Helen Diller Family Comprehensive Cancer Center, and former CEO of thCancer Center, and former CEO of the ICR.

«The research showed that the aggressive form of basal breast cancer cells may be dependent on PLK4 for survival and that depleting it induced cell death,» says Dr. Mak.

A new study finds that more than half of women with early stage breast cancer considered an aggressive type of surgery to remove both breasts.

The discovery of this stem cell could explain why some breast cancers recur despite aggressive chemotherapy.

«What began with the question «what makes a particular aggressive form of breast cancer cells keep growing?»

The family of hCA enzymes contains similar proteins, such as hCA IX and XII, that are associated with aggressive breast cancers, such as triple negative breast cancer.

Women with particularly aggressive forms of breast cancer could be identified by a test that predicts whether the disease is likely to spread to the brain.

Although prolonged breastfeeding reduces overall cancer risk, women have an increased risk of developing breast cancer for the first 5 to 10 years following pregnancy, and these cancers tend to be more aggressive.

Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread.

This provides a potential target for treating triple negative breast cancer, the most aggressive form of the disease.

Previous in vitro studies conducted by researchers in other countries showed that this molecule was able to reduce the multiplication and increase the mortality of cells from melanoma, the most aggressive type of skin cancer, as well as breast cancer and neuroblastoma, a tumor that typically affects patients aged 15 or younger.

When the investigators analyzed the genes of MECs infected with EBV, they found genetic characteristics associated with high - grade, estrogen - receptor - negative breast cancer (an aggressive form of the disease).

It has been recognized that the more aggressive triple - negative breast cancer occurs more frequently in African American women, but no previous study has examined racial differences in tumor genotype and how they might contribute to the risk of cancer recurrence.

«In addition to having a higher prevalence of triple - negative breast cancers than Caucasian women — something that has been documented in previous studies — we found that African American women with breast cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the Cancer Center, lead author of the study.

The discovery offers a new treatment option beyond chemotherapy for this aggressive type of breast cancer.

The results suggest that the pockets of stiffer extracellular matrix in the breasts of obese women contribute to tumor growth as well as to more aggressive cancers, Fischbach says: «People always think it's all about soluble factors, chemicals.

A new study shows coibamide A has potent anti-cancer activity in mice and cell cultures that model brain tumors and triple negative breast cancer, two of the most aggressive and difficult - to - treat types of cancer.

Compared to other types of breast cancer, triple negative breast cancers are often more aggressive and have fewer treatment options.

For years, scientists have observed that tumor cells from certain breast cancer patients with aggressive forms of the disease contained low levels of mitochondrial DNA.

Now, University of Pennsylvania researchers have revealed how a reduction in mitochondrial DNA content leads human breast cancer cells to take on aggressive, metastatic properties.

The team's findings, published online in Nature Cell Biology, explored HIF - 1's role in triple - negative breast cancer (TNBC), an aggressive and hard - to - treat form of the disease.

The growth rate of the cells exploded, and they quickly became disorganized masses characteristic of early stage, aggressive breast cancer, the team reports in the 7 February issue of the Journal of Experimental Medicine.

Further, the relationship between Myc and TXNIP is not observed in other types of breast cancer, suggesting that it is a feature of only aggressive triple negative breast cancers and not other less aggressive breast cancer types.