Sentences with phrase «of aggressive disease»

«We want to test the direct role of these transcription factors in the development of aggressive disease and response to chemotherapy.

For reliable diagnosis of aggressive disease, he said, «we need to have panels, not just rely on a single metabolite.»

In the study, researchers found that, as a group, men prescribed testosterone for longer than a year had no overall increase in risk of prostate cancer and, in fact, had their risk of aggressive disease reduced by 50 percent.

Not exact matches

In the Fresno experiment — the largest one of its kind in the US so far — the Debug Project is targeting the Aedes aegypti mosquito, an aggressive invasive species that can transmit nasty diseases like dengue, Zika, and chikungunya.

This was on my mind when word came out last week that Hitchens was suffering from esophageal cancer, a particularly aggressive and unforgiving form of the disease.

Mothers of 66 children who had celiac disease but didn't know it yet reported more child anxiety and depression, withdrawn behavior, aggressive behavior, and sleep problems when compared to the more than 3,651 mothers of children who did not have celiac disease at all.

Studies have shown that among the many effects of physical abuse are depression, anxiety, cognitive and learning difficulties, even a lowering of IQ (especially verbal IQ), disordered sleep, flashbacks, loss of empathy, aggressive behavior, chronically high stress levels which can lead to chronic health effects such as high blood pressure and increased risk of cardiovascular disease, and inability to maintain relationships.

BOSTON (AP)-- A new report is urging Massachusetts officials take more drastic steps to combat Lyme disease, from launching aggressive public education campaigns to exploring expanded crossbow hunting to cut down on the number of deer that may be carrying ticks.

In December, the Times Union reported many residents in the village and town believe their community has been afflicted by rare and aggressive forms of cancer and thyroid disease.

Dr. Marcus E. Martinez, who runs a family medical practice in Hoosick Falls, told the Times Union last year that he and his father, who opened the practice in 1956, have noted rare and aggressive forms of cancer in patients, as well as thyroid disease and other health problems.

We are concerned also that intensive harvesting for fuel will lead to more aggressive clear - cutting and to increases in emissions of soot particles that contribute to lung disease.»

In 2014, new combination therapies to treat patients with metastatic melanoma hit the market, helping extend the lives of those with this aggressive disease.

«Gene sequencing study reveals unusual mutations in endometriosis: Findings advance search for new ways to classify aggressive forms of the disease.»

He says a molecular test that sorts lesions as more or less aggressive has the potential to help doctors and patients decide how to treat and monitor the progression and control of the disease.

Now, immunotherapy — a type of treatment that harnesses the patient's immune system to combat the disease — represents the future of cancer treatment, with its efficacy being demonstrated in even the most aggressive types of cancer.

DNMT3A is among the most frequently mutated genes in an aggressive type of leukemia, and it plays a significant role in how this disease develops.

Preclinical findings revealed that Myb gives immune cells called regulatory T (Treg) cells the «authority» to control the strength of the immune response depending on the level of «threat», from minor infections to aggressive diseases.

HUNDREDS of infants who die each year from an aggressive form of leukaemia could one day be saved, thanks to the discovery of the disease's weak spot.

«We are not aware of other agents that selectively act on aggressive, distant metastatic disease, so this was a huge surprise to us,» McDonald said.

Researchers at the Universities of Bristol and Oxford found that testing asymptomatic men with PSA detects some disease that would be unlikely to cause any harm but also misses some aggressive and lethal prostate cancers.

PARP inhibitors have shown efficacy for a small group of patients with breast cancer with inherited mutations in BRCA genes, but have failed in the more aggressive triple - negative disease.

«Because the disease is so aggressive, patients may receive no treatment at all or if they are given an option it will be for just one line of treatment, so it's essential that the most suitable treatment is identified quickly.

Diagnosing the aggressive form of the disease is an important unmet need.

According to Dr. Xu, nearly 80 percent of pancreatic cancer cases are diagnosed in the late stages of the disease when «cancer is very aggressive and typically spreading throughout the body.»

But in 2000, a new aggressive strain of the disease was detected in California, though it probably evolved in Africa or Asia, says Mogens Hovmøller of Aarhus University, Denmark.

But although the drug, called finasteride, caused a 25 % reduction in prostate cancer, it also boosted the risk of aggressive prostate cancer among those diagnosed with the disease.

Although there are several ways to remove RB from the cellular machinery, the group found that complete loss, rather than inactivation, of the RB gene was associated with changes in gene - networks closely linked to aggressive disease.

A new, aggressive strain of yellow rust, a fungal disease of wheat, is waiting in the wings, and east Africa isn't the only region at risk.

Women with the variant were at much higher risk for cancer, had more recurrences, were often hit with multiple cancers and were more likely to die from aggressive forms of these diseases.

Researchers have identified a gene that, when mutated, appears to cause the juvenile form of glaucoma, an aggressive form of the disease that can strike teenagers.

Together with clinical researchers, they are preparing treatments for glioblastoma — the most aggressive brain cancer in adults — , Friedreich's Ataxia — a hereditary neurodegenerative disease — , and a type of paediatric brain cancer.

The study evaluated 56 patients with ovarian clear cell adenocarcinoma (CCA), an aggressive form of ovarian cancer that is more likely to be resistant to chemotherapy and to have a poorer prognosis than other forms of this disease.

By age 80, more than 50 percent of men will develop prostate cancer but not all will have the aggressive, deadly form of the disease.

These are indications that areas of diseased tissue could be dying, while other parts of a tumor could be rapidly growing or becoming more aggressive.

As the largest ever genetic study on pigmentation, it will improve our understanding of diseases like melanoma, an aggressive form of skin cancer.

The authors stressed that the long - term reduction in aggressive disease was observed only in men after more than a year of testosterone use, and the risk of prostate cancer did not differ between gels and other types of preparations.

Chemotherapy and other cancer treatments are supposed to get rid of the disease, but a new study finds they can elicit aggressive tumor growth instead, STAT reports today.

Published in the Jan. 12 issue of JAMA Internal Medicine, the study found that many older diabetes patients received aggressive treatment for their disease regardless of their health status and blood sugar levels.

The team therefore analyzed the case history of 890 breast cancer patients and found that low Numb - 1 and -2 levels correlated with an increased risk of aggressive, metastatic disease, particularly for the luminal subtype of breast cancers, which tend to retain a normal, functional copy of the p53 gene.

This is especially concerning because radiation therapy is increasingly being used after mastectomy as a way to further reduce the risk of the cancer returning in women with more aggressive or advanced disease.

BIG BITES An aggressive biter, the Asian tiger mosquito can carry a variety of pathogens that cause debilitating diseases in humans and some domestic animals.

Nevertheless, the survival rate for lung cancer is dismal: 80 percent of patients die within five years of diagnosis largely due to the disease's aggressive tendency to spread throughout the body.

A new study suggests that an aggressive reef competitor — the Threespot Damselfish — may have impeded the recovery of Caribbean long - spined sea urchin populations after a mysterious disease outbreak caused a massive die - off of these animals over three decades ago.

The answer is complicated, he adds, but much of it involves a delicate balancing act among elements of the immune system: while immunity protects us against disease, an overly aggressive immune response may trigger dangerous, even life - threatening, autoimmune reactions in which the body attacks itself.

For most patients — including actor Patrick Swayze, who died this week as a result of this aggressive malignancy — abdominal pain, weight loss and jaundice are the disease's first indicators, and their onset usually occurs after the cancer has metastasized, erasing any possible benefit of surgery.

The report considers whether a recent trend of fewer men being screened may be contributing to the rise, or whether the disease has become more aggressive — or both.

«These findings raise the possibility that by determining the gene expression profile of a patient's tumor, physicians may be able to identify aggressive disease at the outset of diagnosis and start treatment earlier,» said Sungyong You, PhD, an instructor in the Cedars - Sinai Department of Surgery and the first author of the study.

Based on an analysis of existing evidence, published in an opinion article in the Nature Reviews Clinical Oncology journal on January 20, Dr. Narod argues that to achieve a cure, rather than simply delay progression or reoccurrence of the disease, women should be first treated with aggressive surgery to remove all clinically - detectable cancer cells, followed by targeted chemotherapy to the abdomen (intraperitoneal chemotherapy).

Scientists at Cedars - Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk.

A team of researchers led by UC San Francisco scientists has identified a new drug target for triple - negative breast cancer, an aggressive disease subtype that has the poorest outcomes and accounts for as many as one in five cases.