Sentences with phrase «of aggressive therapy»

This is the first population - based study to compare the follow - up intensity of American men with prostate cancer who have not undergone aggressive treatment with those who opted to undergo various forms of aggressive therapy, such as surgery and radiation.

Not exact matches

Swiss pharmaceutical giant Novartis has made waves with a drug pipeline that includes one of the most talked - about experimental cancer therapies in recent years — a treatment called Kymriah that reconfigures the body's own immune cells to become aggressive blood - cancer killers.

giant Novartis has made waves with a drug pipeline that includes one of the most talked - about experimental cancer therapies in recent years — a treatment called Kymriah that reconfigures the body's own immune cells to become aggressive blood - cancer killers.

And another lady who was disruptive and aggressive was cooperative after only a few months of this therapy.

«Unregulated clinics may sound attractive to parents and youngsters seeking aggressive regenerative therapy,» said Best, who is past president of ACSM.

The triggering of PARP enables cancer cells to withstand anti-hormone therapy treatment, causing cells to cultivate and develop into a more aggressive form.

In 2014, new combination therapies to treat patients with metastatic melanoma hit the market, helping extend the lives of those with this aggressive disease.

«This study forms the basis for future research in patients with breast cancer and offers hope for targeted therapy for patients with aggressive triple - negative inflammatory breast cancer,» said lead researcher Mateusz Opyrchal, M.D., Ph.D., Assistant Professor of Oncology at RPCI.

And it may be possible to enhance the power of talking therapy with a new computer - based technique designed specifically to combat aggressive voices, which looks promising from a small pilot study.

Denmeade says the combination of drugs that block testosterone production and receptors, called androgen deprivation therapy, may make prostate cancer more aggressive over time by enabling prostate cancer cells to subvert attempts to block testosterone receptors.

«By understanding how stress accelerates invasion in aggressive breast tumor cells, this work will inform future studies into whether beta - blockers could be a useful adjuvant therapy in the treatment of some aggressive breast cancers.»

A team of researchers from the Hyperbaric Biomedical Research Laboratory at the University of South Florida (USF) doubled survival time in an aggressive metastatic cancer model using a novel combination of non-toxic dietary and hyperbaric oxygen therapies.

This is especially concerning because radiation therapy is increasingly being used after mastectomy as a way to further reduce the risk of the cancer returning in women with more aggressive or advanced disease.

A growing body of evidence suggests that rapid detection of, and aggressive new therapies for, type - 1 diabetes benefit patients in the long run, possibly halting the autoimmune attack on the pancreas and preserving some of the body's ability to make insulin.

Dr Alessandra Ghigo, first author and research fellow in the Department of Molecular Biotechnology and Health Sciences, University of Torino, Italy, said: «Cardiotoxicity of cancer drugs has become an increasing problem in the last decade due to the increasing success of anticancer therapy and aggressive use of these drugs.

«Because of relatively low survival rates and their advancing age, these patients tend to be poor candidates for aggressive therapies, like a bone marrow transplant,» said senior author Catriona Jamieson, MD, PhD, professor of medicine, chief of the Division of Regenerative Medicine at UC San Diego School of Medicine and director of the Stem Cell Research Program at Moores Cancer Center.

A new population - based study from The University of Texas Medical Branch at Galveston showed for the first time that exposure to testosterone therapy over a five - year period was not associated with an increased risk of aggressive prostate cancer.

It's the first CAR - T therapy to come before the FDA, leading a pack of novel treatments that promise to change the standard of care for certain aggressive blood cancers.

Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.

Currently, DCM has no cure as the available medicines only delay the onset of congestive heart failure or the need for aggressive therapies like heart transplantation.

It is commonly thought that bladder cancers that develop after pelvic radiation tend to be aggressive, with high grades and stages, but this study found that the types, grades, and stages of bladder cancer that developed were similar in patients treated with and without radiation therapy.

Leukemia stem cells promote an aggressive, therapy - resistant form of the disease called blast crisis.

In the new study, the researchers used a combination of four different therapies to activate both of the immune system's two branches, producing a coordinated attack that led to the complete disappearance of large, aggressive tumors in mice.

«Antibodies in the blood provide clues to transplant recipients» likelihood of rejection: Presence of certain antibody types may indicate the need for aggressive anti-rejection therapy.»

More precise dosing methods and cellular engineering techniques show promise in the effort to improve treatment of aggressive cancers with personalized cellular therapies, according to new studies from researchers in the Perelman School of Medicine and the Abramson Cancer Center at the University of Pennsylvania and The Children's Hospital of Philadelphia.

This complexity contributes to its aggressive nature and resistance to conventional therapies such as chemotherapy and radiation therapy,» says Fisher, Thelma Newmeyer Corman Endowed Chair in Cancer Research and co-leader of the Cancer Molecular Genetics research program at Massey Cancer Center, professor and chair of the Department of Human and Molecular Genetics at the VCU School of Medicine, and director of the VIMM.

Given such debilitating effects, an aggressive search is on among scientists to find a cure for MS. Currently available therapies are only partially effective, however, in preventing the onset of permanent disability in MS patients.

In the era of personalized cancer therapy, patients with TNBC remain at considerably higher risk of relapse and death than patients with other breast cancer subtypes, due to the aggressive nature of TNBC and the lack of newer targeted therapies for the disease.

Reporting their results Jan. 29 in PLOS ONE (published by the Public Library of Science), researchers say the study validates a tool that would let doctors decide much faster which severely sick children need to receive aggressive life - saving therapy.

However, aggressive, metastatic tumors can become resistant to this type of therapy.

In spite of endocrine therapy to suppress hormone receptor activity or hormone exposure, many patients of hormone - dependent cancers encounter de novo or acquired resistance and require more aggressive treatments.

«Triple - negative breast cancers tend to be more aggressive compared to other types of breast cancers, and being able to predict response to therapy could greatly impact treatment decisions and patient outcomes,» says study author Shaveta Vinayak, MD, oncologist at UH Case Medical Center and Assistant Professor at Case Western Reserve University School of Medicine.

And while life expectancy has increased with better therapies, surgeries, and more aggressive treatment of identified risk factors, depression has come under increasing scrutiny as a risk factor that could make a difference, if properly treated.

Due to the aggressive nature of AML, this disease usually requires intensive treatment, which may include chemotherapy, radiation therapy, immunotherapy and stem cell transplantation.

Therefore, since there cases of resistant and aggressive melanoma phenotypes or resistance to therapy occurs during treatment targeted or invasive treatment should be considered.

Scope: 22 institutions Treatment: CD19 - targeting CAR T - cell therapy Results: 42 % of patients with aggressive large B - cell lymphoma remained in remission after 15 months

His laboratory is investigating genetic markers that predict development of aggressive prostate and breast cancers, and nanotechnology - based therapies for breast and prostate cancers.

«This would be useful and important,» he said, «because physicians could decide to switch or modify therapies if they know whether the patient is likely to have an aggressive course of disease, or a more benign course.»

Doctors are already using drugs, such as Herceptin, that specifically target malfunctioning genetic pathways in tumors, but no such therapies are currently available for certain aggressive forms of the disease, such as the triple negative subtype.

However, approximately twenty percent of meningiomas are aggressive and can recur even after surgery and radiation therapy.

Like the Mississippi child that was thought to have beaten HIV after aggressive anti-retroviral treatment, detectable levels of the virus return in an Italian child who received similar therapy.

This aggressive form of breast cancer does not respond to many common breast cancer medicines, such as hormone therapies.

A small, phase 1 trial, published early online in the journal Radiology, found that this approach, designed to treat just the diseased portion of the prostate rather than removing or irradiating the entire gland, is safe and can be performed without the troubling complications associated with more aggressive therapies.

Most patients die within a few years of diagnosis, despite aggressive therapy.

This model should be a powerful tool for testing therapies for aggressive ER + breast cancers and for studying luminal cancers — the most prevalent and deadliest forms of breast cancer.

Scientists exploit gene therapy to shrink tumors in mice with an aggressive form of breast cancer.

This gene finding may allow scientists to identify patients with this aggressive form of the cancer and target them with additional therapies.

December 13, 2011 Molecular markers can predict spread of cancer, guide treatment Molecular markers found in cancer cells that have spread from a primary tumor to a limited number of distant sites can help physicians predict which patients with metastatic cancer will benefit from aggressive, targeted radiation therapy.

His laboratory is interested in understanding the role of metabolic adaptations in breast and prostate cancer progression, and elucidating mechanisms that promote therapy resistant aggressive metastatic disease.

Despite marked advances in breast cancer therapy, basal - like breast cancer (BBC), an aggressive subtype of breast cancer usually lacking estrogen and progesterone receptors, remains difficult to treat.