Sentences with phrase «of aggressive tumors»

Some studies have found that pets who have microchips are at an increased risk of cancer, particularly of aggressive tumors that grow at the site of the chip.

These two aspects of tumor progression (hypoxia and reoxygenation) cooperate to provide growth advantages essential for the progressive development of aggressive tumors [21].

«Our results show that a diet oriented towards the prevention of aggressive tumors in the prostate should probably include important elements of the Mediterranean diet such as fish, legumes, and olive oil, and suggest that a high intake of fruits, vegetables, and whole grains might not be enough.»

«But we didn't know whether this is a consequence of an aggressive tumor or rather its cause,» says Rudolf Kaaks, epidemiologist at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ).

These cells are thought to break off from the original tumor and circulate in the blood, and may be a sign of an aggressive tumor.

Not exact matches

McCain, who is battling an aggressive brain tumor, left Washington on Sunday to return to his home state of Arizona, CBS News reported.

In 2009 he had been diagnosed with a type of rapidly growing brain tumor called a high - grade astrocytoma that, despite aggressive treatment, eventually evolved into a glioblastoma — the highly malignant brain tumor that also took the lives of Vice President Joe Biden's son, Beau, in 2015 and former Sen. Ted Kennedy in 2009.

Sen. John McCain of Arizona last week revealed he is battling glioblastoma, the most common and aggressive type of malignant brain tumor in adults.

And of course, whatever is left of the tumor post-surgery will continue to be «aggressive».

«Cancer cells disguise themselves by switching off genes, new research reveals: A genome - wide map of the genes switched off in aggressive tumors reveals a «signature».»

Scientists have uncovered how tumor cells in aggressive uterine cancer can switch disguises and spread so quickly to other parts of the body.

This is especially true for multifocal prostate cancer, less aggressive tumors, and cases of prostatitis or prior prostate irradiation, where MRI alone may not give the correct localization and malignancy grade.»

«This research represents a big step forward in understanding why some tumors are more aggressive than others and being able to predict rationally which neoantigens will be the most effective at stimulating an immune response,» said Dr. Balachandran, a member of the David M. Rubenstein Center for Pancreatic Cancer Research at MSK, and corresponding author of the companion study in Nature.

Many biomarkers are available for estimating tumor mass, but a possibly more important aspect of a tumor's pathology is how aggressive it is and how fast it is growing.

Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis.

«It was really surprizing to realize that oncogenic Pik3ca in basal cells induced the formation of luminal tumours, while its expression in luminal cells gave rise to heterogeneous and more aggressive tumors including basal - like tumors,» comments Alexandra Van Keymeulen, the first author of the paper.

A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy.

Conventional, high - dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors» recurrence in more aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered.

«Lower - carb diet slows growth of aggressive brain tumor in mouse models.»

An experimental drug in early development for aggressive brain tumors can cross the blood - brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).

Researchers from the University of Southampton have discovered a potential way of stopping one of the most aggressive types of brain tumor from spreading, which could lead the way to better patient survival.

While there have been improvements in the current standard treatments, patients with glioblastoma (GBM), the most common and aggressive form of brain tumor, still suffer from a median survival rate of only 14.6 months and 5 - year overall survival rates of less than 10 %.

«Study identifies potential treatment target for pancreatic cancer: Molecular signature found in 30 percent of PDAC tumors associated with more aggressive cancer.»

Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue.

A Gleason score of < 6 typically indicates a less aggressive tumor with generally good prognosis.

In this study, we found that chloroquine not only has an effect on the growth of the cancer cells, but also makes the tumor environment less aggressive by normalizing the abnormal blood vessels in the tumor,» says Patrizia Agostinis.

They found aggressive breast tumors, including those that show metastatic traits, expressed higher levels of hnRNPM.

Glioblastoma is the most aggressive type of tumor that originates in the brain and with no curative treatments currently available, the average survival time for patients ranges from 15 to 18 months.

These are indications that areas of diseased tissue could be dying, while other parts of a tumor could be rapidly growing or becoming more aggressive.

The Cancer Vaccine Collaborative is working on treatments that target multiple cancer antigens, which should trigger a more aggressive immune response and increase the odds of defeating tumors.

Importantly, elevated BRCA1 methylation was confined to patients diagnosed with so - called high - grade serous tumors, the most aggressive variant of ovarian cancer, which also is the variant associated with BRCA1 mutations.

However, because of the aggressive way glioblastomas invade surrounding brain tissue, it is impossible to remove all parts of the tumors, and the cancer eventually returns and spreads.

«By understanding how stress accelerates invasion in aggressive breast tumor cells, this work will inform future studies into whether beta - blockers could be a useful adjuvant therapy in the treatment of some aggressive breast cancers.»

Because of this lack of receptors, common cancer drugs can't «find» the cells, and doctors must treat the cancer with extremely aggressive and highly toxic treatment strategies,» said Salman Hyder, the Zalk Endowed Professor in Tumor Angiogenesis and professor of biomedical sciences in the College of Veterinary Medicine and the Dalton Cardiovascular Research Center.

Chemotherapy and other cancer treatments are supposed to get rid of the disease, but a new study finds they can elicit aggressive tumor growth instead, STAT reports today.

Of the 297, 127 people had glioblastoma and 170 had a lower grade glioma, which is also a tumor of glial cells, but less aggressive than glioblastomOf the 297, 127 people had glioblastoma and 170 had a lower grade glioma, which is also a tumor of glial cells, but less aggressive than glioblastomof glial cells, but less aggressive than glioblastoma.

BRAF mutations, which occur in about 40 to 50 percent of these patients, have been associated with aggressive tumors and decreased ability of tumors to respond to radioactive iodine, typically the first line of treatment in these patients.

Recently, teaming up with co-investigator Associate Professor Dr. Rolf A. Brekken, they looked into its possible involvement in Pancreatic Ductal Adenocarcinoma (PDA), the most common form of pancreatic cancer, in a mouse model with an early onset aggressive form of tumor development.

«We found a striking difference between the metabolic profiles of poorly aggressive and highly aggressive ovarian tumor cells, particularly with respect to their production and use of the amino acid glutamine,» said lead researcher Deepak Nagrath of Rice.

«These findings raise the possibility that by determining the gene expression profile of a patient's tumor, physicians may be able to identify aggressive disease at the outset of diagnosis and start treatment earlier,» said Sungyong You, PhD, an instructor in the Cedars - Sinai Department of Surgery and the first author of the study.

Scientists at Cedars - Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk.

Little is known about how CNS - PNETs develop, although these tumors are more aggressive than other PNETs and have an overall survival rate of only about 20 percent.

In tests in mice with a very aggressive form of melanoma, the researchers found they could stop tumor growth by delivering this engineered form of IL - 2, along with antibody drugs, once a week.

«New tumor analysis method identifies high - risk prostate cancer: Cancer cells» genetic pathways show which patients are likely to develop aggressive types of the disease.»

The authors say it is plausible that smokers have pathologically more - aggressive tumors, or that smoking may decrease the efficacy of colorectal cancer treatment.

They found that, by using math models to understand the complex dynamics within cancers, they could use small changes in the environment to promote the growth of cells that are less aggressive and thereby decrease tumor growth.

In the meantime, he adds, gaining a better understanding of aggressive NF1 - related tumors allows researchers to develop more realistic models of these cancers in the lab.

Study leader Fausto J. Rodriguez, M.D., associate professor of pathology at the Johns Hopkins University School of Medicine and member of the Johns Hopkins Kimmel Cancer Center, says the new study sought to sort out what makes the more aggressive NF1 - related tumors genetically different from low grade tumors and normal, healthy cells.

Despite the success of melanoma - targeting drugs, tumors inevitably become drug resistant and return, more aggressive than before.

Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.