Sentences with phrase «of alkaline phosphatase»

Elevations of alkaline phosphatase, one of the enzymes screened on a basic blood panel, bode poorly.

That, in turn, activates an inducible reporter gene, which expresses a secreted form of alkaline phosphatase.

Not exact matches

Low dietary intake of copper may also be associated with increased fecal free radical production and fecal water alkaline phosphatase activity, risk factors for colon cancer.

In animals harboring intraperitoneal hollow - fiber or subcutaneous implants containing light - inducible transgenic cells, the serum levels of the human glycoprotein secreted alkaline phosphatase could be remote - controlled with fiber optics or transdermally regulated through direct illumination.

Since alkaline phosphatase, coupled to the secondary antibody for the BrdU primary antibody, may have complicated the interpretation of the wounding experiments, we also treated human corneal - limbal tissues with BrdU histochemical assays in which fluorescein, rather than alkaline phosphatase, was coupled to the secondary antibody.

Flat mounts of the corneas were made, treated with BrdU, primary antibody, and then stained by reacting with alkaline phosphatase - linked secondary antibody.

Interestingly, alkaline phosphatase is also indicative of stem cell presence [29].

Next they were covered on the endothelial side with a 1:10 dilution of anti-mouse-Ig secondary antibody coupled to alkaline phosphatase.

Liver functions were assessed using a panel of biochemical tests indicating liver inflammation (aspartate amino transferase and alanine amino transferase), cholestasis or biliary obstruction (total bilirubin and alkaline phosphatase) and synthetic function (albumin).

Ohkubo et al. «Ecto - Alkaline Phosphatase in NG108 - 15 Cells: A Key Enzyme Mediating P1 Antagonist - Sensitive ATP Response», British Journal of Pharmacology, 131 (8): 1667 - 1672, 2000.

When five lines were further expanded and characterized, all demonstrated expression of key pluripotency markers expressed by hESCs, which included: alkaline phosphatase, Nanog, SSEA3, SSEA4, TRA160 and TRA181 (Figure 5A).

Polycistronic cassettes that contained the KLF4L isoform had more robust initiation of reprogramming (evaluated by an alkaline phosphatase - positive assay) as well as stabilization (Nanog - GFP reporter activation and silencing of factor - linked mCherry).

Also what could it mean if alkaline phosphatase was high instead of low?

Higher levels of IAP: Type Os also possess a higher amount of an enzyme called intestinal alkaline phosphatase, or IAP.

It stimulates the production of calcitonin, the hormone responsible for inhibiting cells (osteoclasts) that breaks bone down and activates alkaline phosphatase, an enzyme that forms new calcium crystals in bones.

(Improved bone health markers have included a decrease in the number of cross-linked telopeptides and a decrease in blood levels of bone specific alkaline phosphatase.)

Abnormal liver tests consist of mild - to - moderate elevations of ALT and AST but marked elevation of serum alkaline phosphatase levels, reflecting interference with bile drainage.

(CRT) Dogs that have heartworms discovered later in life often have elevated liver and kidney tests (serum AST, ALT, alkaline phosphatase, bilirubin, and urea nitrogen) Those dogs are also high - risk candidates for the use of melarsomine.

Serum ALT and alkaline phosphatase are occasionally increased, but do not correlate well with abnormal liver function, efficacy of adulticide treatment, or risk of drug toxicity.

ALP (Alkaline Phosphatase) may also be elevated in the case of liver disease, drug administration or any inflammatory processes in the body.

Elevations of «Alkaline phosphatase,» one of the enzymes screened on a basic blood panel, bode poorly.

ALKALINE PHOSPHATASE elevations may indicate liver damage or can also be a result of active bone growth in young kittens.

Grant 395 - A (2007) Elevated Serum Alkaline Phosphatase Activity I Scottish Terriers: Benign Hyperphosphatasemia or Indicator of Disease?

Generally (very generally) in a case of fatty liver disease you would expect an increase in circulating bilirubin, more than a two fold increase in aspartate aminotransferase (AST), alkaline phosphatase (ALP) and alanine aminotransferase (ALT) along with a normal or mildly increased gamma - glutamyl transferase (GGT) level I added a link to a biochemistry reference page for comparison.

Solter PF, Hoffmann WE, Hungerford LL, Peterson ME, Dorner JL: Assessment of corticosteroid - induced alkaline phosphatase isoenzyme as a screening test for hyperadrenocorticism in dogs.

At the end (but not at the beginning) of the trial, hemoglobin, packed cell volume, serum alkaline phosphatase, and serum albumin are measured and recorded.

In most dogs, a liver enzyme called serum - alkaline phosphatase (SAP) will be elevated in the presence of high cortisol levels.

ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)

Other clinicopathologic abnormalities may include high serum concentrations of triglycerides, alkaline phosphatase, and CK.

In dogs with primary tumors, the alkaline phosphatase (hydrolase enzyme responsible for removing phosphate groups from many types of molecules), alanine transferase (enzyme found in the liver and other tissues) are usually elevated.

Prognosis of patients with this disease depends on multiple factors, the most commonly cited including: presence of metastasis (negative), elevated alkaline phosphatase (negative), large tumor size (negative), humerus location (negative), treatment chosen (dogs receiving amputation and chemotherapy have improved survival times over dogs receiving amputation alone) 1.

A unique difference in liver enzyme activity contrasting with other feline cholestatic liver disorders is the relative inactivity of γ - glutamyltransferase compared with alkaline phosphatase.

Other standout lots were the very strong «Self Portait as a Heel - Part Two,» by Jean - Michel Basquiat (1960 - 1988), Lot 16, shown at the top of this article, an acyrilic and oil paintstick on canvas, 1982, that sold for $ 772,500, well above its high estimate of $ 600,000; two sculptures by Agnes Martin (b. 1912), Lots 17 and 18, which sold for $ 217,000 and $ 233,500, respectively, both considerably over their respective high estimates of $ 45,000 and $ 120,000; «Broadway and 64th Street,» a very good, large oil by Richard Estes (b. 1932), that sold above its $ 300,000 high estimate for $ 354,500; Lot 31, a large canvas from his Rorschach series by Andy Warhol (1928 - 1987) that more than doubled its high estimate and sold for $ 684,500; Lot 13, «Alkaline Phosphatase - Polyethelene Glycol,» by Damien Hirst (b. 1965), 1992, sold for $ 140,000 and had a high estimate of $ 80,000; and Lot 37, «a delightful large acrylic on vinyl tarpaulin by Keith Haring (1958 - 1990) that sold for $ 200,500 and had a high estimate of $ 150,000.