Fleas are the worldwide number one cause
of allergic dermatitis in dogs and cats.
«Fleas are a major contributor to the production
of allergic dermatitis in dogs,» said Michael W. Dryden, DVM, PhD, DACVM, Department of Diagnostic Medicine / Pathobiology at Kansas State University, Manhattan, Kan., and lead author of the study.
Food allergies are now estimated to be the second leading cause
of allergic dermatitis in cats.
There are many causes
of allergic dermatitis in dogs.
Not exact matches
Contact
dermatitis rash is usually only found on the part
of the skin that came
in contact with the item your baby is
allergic to.
Peru's Social Health Insurance also mobilized doctors and nurses to the district
of Imaza, one
of the affected areas,
in response to the cases
of allergic dermatitis, pharyngitis, bronchitis and gastroenteritis that have been reported following work on the containment and collection
of the oil spill.
Besides causing a swelling
of the mouth or the mucous membranes, other symptoms can include diarrhea or aggravated atopic
dermatitis, and,
in rare cases, can even induce an
allergic shock.
Scientists from the National Institute
of Allergy and Infectious Diseases (NIAID), part
of the National Institutes
of Health, and other institutions discovered the mutations
in four unrelated families with severe atopic
dermatitis and studied the resulting cell - signaling defects that contribute to
allergic disease.
Further studies discovered that the BRAF protein could turn on many itch genes, and they showed similar changes
of gene expression
in mice with chronic itch induced by dry skin and
in mice with
allergic contact
dermatitis, two
of the skin conditions that frequently cause people to scratch incessantly.
Both
of these symptoms are common
in allergic contact
dermatitis, which affects more than 10 million patients a year
in the United States alone.
Cruse and Metcalfe tested their therapy on mast cells
in vitro — where it eliminated activation
of mast cells by allergen — and against
allergic dermatitis in vivo, using a mouse model.
Accumulation
of metal - specific T cells
in inflamed skin
in a novel murine model
of chromium - induced
allergic contact
dermatitis.
Stephen Alexander, UK - Cannabinoid receptors, transporters, endocannabinoid turnover, hydrogen sulphide turnover Arthur Christopoulos, Australia (GPCRs Liaison)- G protein - coupled receptors; analytical pharmacology; allosteric modulation; biased agonism; drug discovery; neuropharmacology John Cidlowski, USA (NHRs Liaison)- Glucocorticoid receptor signaling; apoptosis and the immune system Anthony P. Davenport, UK (Chair Evolving Pharmacology, GPCRs Liaison) Doriano Fabbro, Switzerland - Kinases and their biology, kinase inhibitors, drug discovery, pharmacology
of drugs (kinase inhibitors)
in the indication oncology, biology
of oncology Kozo Kaibuchi, Japan Yoshikatsu Kanai, Japan - Transporters, amino acid signals, epithelial function, cancer biology Francesca Levi - Schaffer, Israel - eosinophils and mast cells as effector cells
in allergic inflammation: characterization
of new receptors / ligands, hypoxia / angiogenesis and eosinophils, asthma, atopic
dermatitis,
allergic rhinitis, immunopharmacological modulation
of allergic diseases by bispecific recombinant antibodies, bacteria interactions with eosinophils and mast cells, the
allergic effector unit, mast cell derived tumors: new antibody based treatment, the
allergic inflammation and the resolvome, non IgE - mediated mast cell activation
in diseases Eliot H. Ohlstein, USA (Editor)- Drug discovery and development, urogenital biology, cardiovascular / metabolic medicine John A. Peters, UK (LGICs Liaison) Alex Phipps, UK - Oncology, Clinical Pharmacology, Biologics and Immunotherapy Joerg Striessnig, Austria (VGICs Liaison)- Physiology, pharmacology and pathophysiological role
of voltage-gated calcium channels
Maternal intake
of probiotics protects against
allergic diseases
in children such as atopic
dermatitis.
Probiotics have been cited
in more than 200 studies to help manage
in excess
of 170 types
of health conditions like Irritable Bowel Syndrome, Atopic
Dermatitis, Diarrhea and
Allergic Rhinitis to name a few.
In addition to «sensitizing
dermatitis,» stubborn symptoms that might be the result
of nickel toxicity include
allergic asthma, acid reflux, insomnia and snoring.52
We've seen the most extraordinary results
in our clients with rosacea,
allergic dermatitis, eczema and all types
of inflammation that goes far beyond its reputation for conquering severe and cystic acne.
Pruritus or itching is one
of the cardinal signs
of allergic dermatitis whereby proteinaceous molecules on the surface
of substances inadvertently trigger an immunologic response
in dogs.
APOQUEL is the only animal health product approved for both the control
of pruritus associated with
allergic dermatitis and the control
of atopic
dermatitis in dogs over 12 months
of age.
It is primarily indicated
in the control
of pruritus secondary to
allergic dermatitis.
Atopy (
allergic inhalant
dermatitis) occurs
in approximately 10 % to 15 %
of the dog population, usually starting between the ages
of 1 and 3 years.
While the cause
of the skin inflammation can be determined
in allergic dermatitis, the same can not be said
of atopic
dermatitis.
Atopic
dermatitis in canines can be linked to a dysfunction
in the skin barrier that increases the absorption
of the allergens, making the development
of an
allergic reaction more likely.
Control
of pruritus (itching) associated with
allergic dermatitis and control
of atopic
dermatitis in dogs at least 12 months
of age.
Efficacy and safety
of oclacitinib for the control
of pruritus and associated skin lesions
in dogs with canine
allergic dermatitis.
When it comes to causing
allergic reactions
in dogs, a number
of factors can be culprits — from fleas to atopic
dermatitis.
In some cases the dog may develop an
allergic reaction to the flea bites and show signs
of dermatitis.
32 hours
of continuing education including: The hyperthyroid cat with renal failure, feline hepatic lipidosis prevention and treatment, Atkins diet for dogs and cats, cancer and non-steroidal drugs, ear flushing and medical treatment
of otitis externa, dealing with the
allergic dog, urinary obstruction and incontinence, managing the neonate, aggression
in cats, and canine atopic
dermatitis.
The dog's
allergic dermatitis was attributable to at least one
of the following: food allergy, contact allergy, flea allergy, atopic
dermatitis, sarcoptic mange, unspecified
allergic dermatitis (unless prohibited
in exclusion criteria)
Indications Control
of pruritus associated with
allergic dermatitis and control
of atopic
dermatitis in dogs at least 12 months
of age.
A masked, multisite, well - controlled study
of 436 dogs conducted at 26 veterinary clinics
in the US evaluated the effectiveness and safety
of APOQUEL, dosed orally twice daily (BID) at 0.4 to 0.6 mg / kg for the control
of pruritus associated with
allergic dermatitis, including flea allergy, food allergy, contact allergy and atopic
dermatitis
«
In my 28 years of practice, this is the most exciting new treatment for the management of itch associated with allergic and atopic dermatitis in dogs, which can often be a challenging and complex condition to treat.&raqu
In my 28 years
of practice, this is the most exciting new treatment for the management
of itch associated with
allergic and atopic
dermatitis in dogs, which can often be a challenging and complex condition to treat.&raqu
in dogs, which can often be a challenging and complex condition to treat.»
In a trial
of dogs with
allergic dermatitis, APOQUEL produced rapid onset
of efficacy within 24 hours.
In addition, pets who have other allergies, such as flea
allergic dermatitis (which occurs for 20 - 30 %
of soy allergy patients), are at risk for allergies
of varying types.
The development
of allergic dermatitis requires two things: a dog with a genetic predisposition to developing allergies and an allergen
in the environment to incite the
allergic response.
Many aspects
of ALD are similar to
allergic dermatitis in general.
Given the complexities described
in the pathways leading to
allergic dermatitis, you should not be surprised to receive a small pharmacy's worth
of prescriptions when your dog is diagnosed with
allergic dermatitis.
Florham Park, N.J. — August 13, 2013 — Results
of a new pivotal study show that APOQUEL ® (oclacitinib tablet) provides effective and safe control
of pruritus associated with
allergic dermatitis in dogs with a rapid onset
of efficacy within 24 hours and without the commonly reported side effects
of steroids.
Environmental allergens (such as ragweed, pollens, grasses, trees, molds, etc) have long been suspected as being a major factor
in flare - ups
of canine seasonal
allergic dermatitis (known as atopy).
Some
of the factors that can lead to Malassezia
dermatitis include moisture (as
in dogs with skin folds or floppy ears with narrow ear canals), excessive waxy or scaly build - up (as
in seborrhea), and
allergic and bacterial skin disease.
About the Study The study, «Efficacy and safety
of oclacitinib for the control
of pruritus and associated skin lesions
in dogs with canine
allergic dermatitis,» was conducted as a double - masked, placebo - controlled clinical trial aimed to evaluate the safety and efficacy
of APOQUEL compared with placebo.
APOQUEL is the only animal health product approved for the control
of pruritus associated with
allergic dermatitis and the control
of atopic
dermatitis in dogs over 12 months
of age.
Then there were Mitral valve 42 cases, Heart Murmer 36 cases, Epilepsy 33 cases,
Allergic dermatitis 29 cases, and Glaucoma 24 cases with most cases being diagnosed
in dogs over 7 years
of age.
Allergic dermatitis is very common, and can manifest
in dogs through constant chewing
of their feet, itching, and licking, which can cause scabs, rashes, hair loss, and worse if not addressed properly.
The fact
of the matter is that parasites can cause
allergic reactions
in pets, especially those who have a confirm cases
of flea
dermatitis — an allergy to fleas, their saliva and bites.
Examples
of substances that can result
in allergic contact
dermatitis include poison ivy and other plants, fragrances and dyes, certain metals including nickel (a common metal
in collars), rubber, and preservatives
in skin care and other products.
Allergic contact
dermatitis is the result
of an allergy to something that comes
in contact with the skin.
Flea bite
dermatitis is an
allergic skin condition
in dogs that are
allergic to the saliva
of fleas.
In a trial of dogs with allergic dermatitis, treatment success, as defined by owner - assessed decrease in pruritus, occurred in 67 percent of dogs treated with APOQUEL vs. 29 percent of dogs treated with placebo after one week of treatmen
In a trial
of dogs with
allergic dermatitis, treatment success, as defined by owner - assessed decrease
in pruritus, occurred in 67 percent of dogs treated with APOQUEL vs. 29 percent of dogs treated with placebo after one week of treatmen
in pruritus, occurred
in 67 percent of dogs treated with APOQUEL vs. 29 percent of dogs treated with placebo after one week of treatmen
in 67 percent
of dogs treated with APOQUEL vs. 29 percent
of dogs treated with placebo after one week
of treatment.
Flea preventives should always be started
in the case
of miliary
dermatitis, because symptomatic cats are very likely to be
allergic to flea bites.