Here, I discuss a novel computational approach for the detection
of allostery in protein complexes by way of molecular dynamics simulation and advanced data reduction protocols.
While the importance
of allostery is well appreciated, a clear understanding of the process still eludes modern science.
Still, the rewards far outweigh the frustrations, as an understanding
of allostery can lead to the physical control of molecular switches and downstream cellular responses.
Not exact matches
Elastic strain and twist analysis
of protein structural data and
allostery of the transmembrane channel KcsA