Sentences with phrase «of amyotrophic lateral sclerosis in»

Dietary exposure to the cyanotoxin BMAA is suspected to be the cause of amyotrophic lateral sclerosis in the Western Pacific Islands.

Not exact matches

This vital connection between word and life is evident in the story of a man suffering from a fatal motor neurone disease, called amyotrophic lateral sclerosis.

Drink One for Dane, held every May, in honor of late Co-founder Dane Boersma, which raises funds for research into cause and cure for amyotrophic lateral sclerosis (ALS) and support for families facing the realities of the disease.

A professor of European History at New York University (NYU), founder and director of the Erich Maria Remarque Institute at NYU, frequent contributor to The New York Review of Books, and public intellectual, Judt's plan for his next book mothballed, as personal history intervened in the form of Amyotrophic Lateral Sclerosis (ALS), otherwise known as Lou Gehrig's disease.

Scientists at the UNC School of Medicine have made a significant advance in the understanding of the complex and fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

For example, RNA - binding proteins are overexpressed in many human cancers, and mutations in some of these proteins have been linked to neurological and neurodegenerative disorders such as amyotrophic lateral sclerosis.

In a preliminary analysis published November 2009 in the journal Amyotrophic Lateral Sclerosis, living near a bloom or the site of a former bloom more than doubled the risk of ALIn a preliminary analysis published November 2009 in the journal Amyotrophic Lateral Sclerosis, living near a bloom or the site of a former bloom more than doubled the risk of ALin the journal Amyotrophic Lateral Sclerosis, living near a bloom or the site of a former bloom more than doubled the risk of ALS.

Others credit Hawking for working on important problems in spite of the degenerative nerve disease, amyotrophic lateral sclerosis, that led to his use of a wheelchair and eventually rendered him able to speak only through a computerized voice synthesizer.

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, might damage muscle - controlling nerve cells in the brain earlier in the disease process than previously known, according to research from the Cedars - Sinai Board of Governors Regenerative Medicine Institute.

Amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, is marked by a cascade of cellular and inflammatory events that weakens and kills vital motor neurons in the brain and spinal cord.

Hawking, who spent his entire career at the University of Cambridge, suffered from amyotrophic lateral sclerosis, a degenerative nerve disease with which he was diagnosed in his 20s.

They're relevant in the context of treating diseases like amyotrophic lateral sclerosis, a motor neuron degenerative disease that starts with weakness in the extremities and eventually leads to complete loss of all motor function.

Since Lipton's group co-discovered the SNO reaction some 20 years ago, scientists have linked the reaction to protein misfolding and nerve cell damage in cases of Alzheimer's, Huntington's, amyotrophic lateral sclerosis (ALS / Lou Gehrig's disease) and Parkinson's disease, as well as heart / cardiovascular disease and cancer.

Last May in Nature Neuroscience, his lab and a team at Columbia University reported that embryonic stem cells could be used to shed light on the origins of amyotrophic lateral sclerosis (ALS), the progressive neurodegenerative disease in which motor neurons in the brain die.

Experiments in mouse models of Parkinson's disease and amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease) have demonstrated that Nrf2 - based neural protection is primarily conferred by astrocytes, but how neurons might alert astrocytes to stressful conditions is poorly understood.

It is famous for robbing Lou Gehrig of his life and Stephen Hawking of his mobility and voice, but just how amyotrophic lateral sclerosis (ALS) destroys motor neurons in the brain and spinal cord remains a mystery.

In a particularly dramatic demonstration at the Stanford site of the pilot clinical trial, a woman identified as «T6,» who is diagnosed with amyotrophic lateral sclerosis, was able to use BrainGate for six sessions of a few hours each over the course of 42 days without any interruptions for explicit recalibration after the decoder was initialized on the first day.

A bacterial by - product known to be important in maintaining gut health may slow the progression of amyotrophic lateral sclerosis, or ALS — a progressive, neurodegenerative disease.

A relatively rare inherited disease in which the nerves that control movement mysteriously degenerate and disappear, it is the childhood equivalent of the better - known (but no better understood) amyotrophic lateral sclerosis.

In 1963, while a graduate student at the University of Cambridge, he was told he had amyotrophic lateral sclerosis, or Lou Gehrig's disease, a diagnosis that usually proves fatal within five years.

The same treatment killed many other types of neurons, including both the spinal motor neurons that die in amyotrophic lateral sclerosis and the human dopaminergic neurons whose mysterious loss is the cause of Parkinson's disease.

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle - controlling nerve cells — motor neurons — in the brain, brainstem and spinal cord, leading to progressive weakness and eventual paralysis of muscles throughout the body.

In their first study, Gray and colleagues analyzed the emotional content of blog posts from terminally ill patients who were dying of either cancer or amyotrophic lateral sclerosis (ALS).

Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), both of which are caused by a mutation in the a gene called C9ORF72.

A team of researchers at Mayo Clinic and The Scripps Research Institute in Florida have developed a new therapeutic strategy to combat the most common genetic risk factor for the neurodegenerative disorders amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and frontotemporal dementia (FTD).

A study published Tuesday in eLife reports the results of a system that enabled three participants — Degray and two people with amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease, a neurodegenerative disease that causes progressive paralysis)-- to type at the fastest speeds yet achieved using a BCI — speeds that bring the technology within reach of being practically useful.

In the medium term, the approach should contribute to the development of treatments for paralytic diseases such as infantile spinal muscular amyotrophy or amyotrophic lateral sclerosis.

Johns Hopkins researchers say they have discovered some of the first steps in how a very common gene mutation causes the brain damage associated with both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

Scientists have identified the molecular mechanism that leads to the death of neurons in amyotrophic lateral sclerosis (also known as ALS or motor neurone disease) and a common form of frontotemporal dementia.

Accumulation of misfolded protein aggregates is not only present in T2D but also is the main feature of a group of diseases known as protein misfolding disorders (PMDs), including various neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and prion disorders, as well as several systemic amyloidosis disease (Luheshi et al., 2008; Soto and Estrada, 2008).

The most common genetic cause of the brain diseases frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) is a mutation in the C9orf72 gene.

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a debilitating neurodegenerative disorder that leads to paralysis and death due to the loss of motor neurons in the brain and spinal cord.

S. Stefanie, H Bettina, Nilges M, Schroeder S, Hoelich A, Keletzl H, Spooren W, Ostrowitzki S, Hanania T, Sendtner M, Metzger F. Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin - like growth factor I treatment depends on disease severity.

Intrathecal administration of an antisense drug, ISIS - SOD1Rx, has been shown to be safe and well tolerated in an ongoing Phase 1 study in patients with amyotrophic lateral sclerosis.

Syracuse University researchers are making strides in understanding the disease mechanism of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

So, this drug also has been tested in cancer trials and also in some of the neurodegenerative diseases, such as multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS).

Animal gait is affected in models of human disorders such as Parkinson's Disease, Multiple Sclerosis, Amyotrophic Lateral Sclerosis, spinal cord injury and many others.

Memory disturbances occur in several neurodegenerative diseases, and we have developed models of several of them including Huntington's disease (HD), Parkinson's Disease (PD), amyotrophic lateral sclerosis (ALS) and Alzheimer's disease.

Her thesis was entitled «Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP - 43 model of Amyotrophic Lateral Sclerosis.»

The presentation, entitled «Ibudilast — Phosphodiesterase Type 4 Inhibitor — Bi-Modal Therapy with Riluzole in Early Cohort and Advanced Amyotrophic Lateral Sclerosis (ALS) Patients — Final Report and Future Directions «(Source) will be presented by principal investigator of the clinical study, Dr. Benjamin Rix Brooks, of the Carolinas HealthCare System's Neuromuscular / ALS - MDA Center at Carolinas HealthCare System Neurosciences Institute.

Dr Brooks will be presenting the results of a single - center, randomized, double - blind, placebo - controlled clnical trial which was conducted to evaluate the safety, tolerability and clinical endpoint responsiveness of a drug called Ibudilast (or MN - 166) in subjects with the neurodegenerative condition, Amyotrophic Lateral Sclerosis (or ALS — also known as motor neuron disease; Click here to read a previous SoPD post about ALS and Click here to learn more about this clinical trial).

The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis.

Researchers from the University of California, San Diego (UCSD) School of Medicine, the Center for Neurologic Study and Isis Pharmaceutical Corporation have designed and tested a molecular therapy in animals that they hope will be a major development in the fight to treat amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease.

The findings may also aid in finding a cure for other neurodegenerative diseases, such as amyotrophic lateral sclerosis and some forms of dementia.

Diagnosed with in a very rare early - onset, slow - progressing form of Amyotrophic lateral sclerosis (ALS; also known as motor neurone disease or MND) in 1963 at age 21, he was gradually left him wheel chair bound.

Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis.

Biological markers of Mesenchymal Stromal Cells as Predictors of response to Autologous Stem Cell Transplantation in Patients with Amyotrophic Lateral Sclerosis; an Investigator - Initiated Trial and in Vivo Study.

Amyotrophic lateral sclerosis (ALS) is a form of motor neuron disease and is the subject of a paper in JAMA Neurology which reports that environmental pollutants measured in the blood were associated with the disease.

A new kind of genetically engineered mouse and an innovation in how to monitor those mice during research have shed new light on the early development of an inherited form of amyotrophic lateral sclerosis (ALS).

BM - MNCs are another cell population under extensive evaluation in clinical trials for treatment of cardiovascular diseases and for peripheral vascular disease, including critical limb ischemia, as well as for amyotrophic lateral sclerosis (ALS), stroke, obstructive pulmonary disease and more.