Sentences with phrase «of an embryonic stem cell with»

To find those genes, Yamanaka had compared all the genes (the genome) of an embryonic stem cell with those of an adult cell to find genes that were turned on in the ES cell but turned off in the adult cell.

Not exact matches

The fundamental impediment to our acceptance of embryonic stem cell research has to do with destruction of the human embryo.

Benedict argued that non-conjugal reproduction such as in vitro fertilization had created «new problems» ¯ the freezing of human embryos, for instance, and the selective abortion of medically implanted embryos, together with pre-implantation diagnosis, embryonic stem - cell research, and attempts at human cloning.

research; since most of the reports have concentrated on justifying the creation of cloned human embryos for research into and treatment of neurodegenerative diseases such as Parkinson's, «stem - cells» has become synonymous with «embryonic stem - cells» in the public imagination.

Rather, embryonic stem cells have already undergone epigenetic restriction and can not produce an organized body with all of its required parts.

In «Stem Cells: A Political History» (November 2008), Joseph Bottum and Ryan T. Anderson make a plausible sounding case that the errors manifest in politicizing the science of embryonic stem - cell research will cause people to be more prudent in the future about mixing science with politics in geneStem Cells: A Political History» (November 2008), Joseph Bottum and Ryan T. Anderson make a plausible sounding case that the errors manifest in politicizing the science of embryonic stem - cell research will cause people to be more prudent in the future about mixing science with politics in genestem - cell research will cause people to be more prudent in the future about mixing science with politics in general.

Not surprisingly, President Obama received high marks from the journal, largely because his response to the question of whether he would lift Bush's ban on the federal funding of new embryonic stem - cell lines is in line with the view of most in the scientific community.

In fact, when the 2007 paper came out, the commentaries in most scientific publications were quick to point out that, despite the success with adult cells, there was still a need to continue embryo - destructive research and that it would be critical to the advancement of science that research on embryonic stem cells continue.

In 2005, before a Congressional hearing in the U.S., Prof. George Q. Daley of Harvard spoke forcefully and influentially about the necessity for embryonic stem - cell research to go ahead, and dismissed suggestions that one could work instead with «induced pluripotent stem cells» («iPS», i.e. stem cells reprogrammed from some cells of a living adult).

Since embryonic stem - cell research systematically kills thousands of unborn babies, a practice that only orcs would contemplate in Middle - earth, it is clear that Jackson and Walsh have sided with the Dark Lord.

He decreed that the case brought by researchers Drs James Sherley and Theresa Deisher, along with a number of Christian groups including the Christian Medical Association, should be heard; and ordered an injunction temporarily blocking federal funding allocated for human - embryonic - stem - cell research.

Another possible advantage of using the Dolly method to produce embryonic stem cells is that it takes just days, compared with weeks for iPS cells.

Advocates of embryonic stem cell research were thought to be in a long line of pioneers fighting the restraints of religious doctrine to push forward with scientific research.

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

Trials of cells made from human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem cells have been used in the treatment of major lethal diseases.

Faced with an often - hostile Congress, Obama enacted many of his signature policies by executive order — from reversing restrictions on research with human embryonic stem cells to helping communities prepare for climate change.

For example, a consortium of research groups called the London Project to Cure Blindness aims to test RPE transplants from embryonic stem cells in patients with macular degeneration this year.

But he notes that long - standing uncertainties surrounding European patents of techniques based on embryonic stem cells have meant that scientists and their attorneys are used to coming up with workarounds to protect discoveries.

The latest findings show that genetic defects in the body's ability to manufacture carnitine might be associated with an increased risk of autism because carnitine deficiency interferes with the normal processes by which neural stem cells promote and organize embryonic and fetal brain development.

Peter Coffey, a stem - cell biologist at the Institute of Ophthalmology in London, is developing an embryonic - stem - cell treatment for macular degeneration with the global drug company Pfizer.

Base oxidation regulates gene activity In cooperation with colleagues at LMU, as well as researchers based in Berlin, Basel and Utrecht, Carell and his group have now shown, for the first time, that a standard base other than cytosine is also modified in embryonic stem cells of mice.

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

Eighteen adults with severe eye disease who were among the first people to receive transplants created from human embryonic stem cells (hESCs) continue to have no apparent complications with the introduced cells after an average of nearly 2 years, according to the latest status report on their health.

In people with severe eye disease, transplants made from embryonic stem cells (in region of black dotted circle) appear safe, and became larger and more pigmented over time (right).

Collins and others argue not just for a permanent removal of the injunction to resume research with confidence, but also for an extension of the number of embryonic stem cell lines available to federally funded researchers.

Twelve people with Stargardt's macular dystrophy will be treated with retinal cells made from human embryonic stem cells (hESCs) in the hope of improving, or at least halting loss of sight.

With a history of public blunders, can Advanced Cell Technology make embryonic stem - cell therapies a realCell Technology make embryonic stem - cell therapies a realcell therapies a reality?

«We can work with any embryonic stem cell line from any source and are not restricted to working with the very small number of federally approved lines as is the case for researchers in the United States,» says Minger.

Scientists anticipate that they'll be able to use iPS cells for much of the research they have been planning with human embryonic stem (ES) cells.

In May 2005, Hwang and his colleagues reported that it had produced 11 new human embryonic stem (ES) cell lines that carried the genetic signature of patients with diabetes, spinal cord injury, or a genetic blood disorder (Science, 20 May, p. 1096).

In collaboration with Ding, the lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis virus.

The research team used mass spectrometry to compare phosphorylation of proteins from mouse embryonic stem cells with fully functioning GSK - 3 to cells in which the gene encoding GSK - 3 had been deleted.

So bear with me for a minute on a couple of very broad themes that I think human embryonic stem cells opened the door to.»

Although primed, post-implantation embryonic stem cells can still turn into any type of human cell, they are more difficult to work with than the pre-implantation, naive cells.

For the purpose of additional experiments, the researchers generated myocardial cells from embryonic stem cells and human skin cells, in collaboration with the lab headed by Prof Dr Jürgen Hescheler at the University of Cologne.

On the other hand, the problem is, you know, with embryonic stem cells, they haven't been able to get stem cell lines from livestock animals that can proliferate in that way, without just sort of veering up in their own direction and turning into, instead of muscle, turning into brain tissue or bone tissue or something else.

The final guidelines on research with human embryonic stem cells issued on Monday by the National Institutes of Health set out criteria for determining which ES cell lines can be used in federally funded experiments and give NIH discretion to approve old lines that don't meet stringent modern ethical requirements.

A clinical trial in the Republic of Korea for patients with degenerative eye diseases is the first to test the safety of an embryonic stem cell therapy for people of Asian descent.

But even more far - ranging treatments may be possible with embryonic stem cells, the blank - slate cells that give rise to all organs and tissue types and that (theoretically) can repair all forms of organic damage and disease.

Stem cells from adult bone marrow normally generate bone, muscle, cartilage and fat cellsa limited set compared with embryonic stem cells, which can spawn the full spectrum of adult tissStem cells from adult bone marrow normally generate bone, muscle, cartilage and fat cellsa limited set compared with embryonic stem cells, which can spawn the full spectrum of adult tissstem cells, which can spawn the full spectrum of adult tissues.

Yamanaka's group and two others followed up earlier this year with firmer evidence that these induced pluripotent stem (iPS) cells faithfully mimicked the patterns of gene activity and cellular differentiation observed in embryonic stem cells.

Around the same time, Yoshiki Sasai of the RIKEN Center for Developmental Biology in Kobe, Japan, cultured the first brain organoids, starting not with adult stem cells but with embryonic stem cells.

Lanza previously led a clinical trial in the United States — published November 2014 in the Lancet — that demonstrated embryonic stem cells could be used safely for patients with degenerative eye diseases, but the patient sample was Caucasian with the exception of one African - American.

There is evidence that chronic disabilities such as spinal cord lesions, diabetes, and Parkinson?s disease, where replacement of just one cell type restores tissue function, can be treated with differentiated embryonic stem cells.

But if homologous recombination could be worked out in human (embryonic) stem cells, then cardiomyocytes with mutations in ion channels could be derived, as well as a large number of other very useful disease models of other tissues.

Now it turns out that IPS cells — just like embryonic stem cells — are fraught with problems of their own.

Twenty percent of the cells cloned in this way grew into early embryos, called blastocysts, and 5 percent of them yielded embryonic stem cells, which is comparable with results obtained from unfertilized eggs.

When he injected mice with embryonic stem cells genetically identical to the mice's own tissues, the new cells thrived, growing into a large clump of adult tissues.

- Our results provide new insights into the mechanisms of how POLR3G gene regulates stem cell state, which in turn sheds light on the complex mechanisms with which human embryonic stem cells both self - renew and maintain the ability to differentiate.

In a statement put on the Web this morning, NIH reported that all 64 lines «show characteristics of stem cell morphology» and have undergone several population doublings, and most of them have demonstrated all the protein markers «known to be associated with human embryonic stem cells.»