Sentences with phrase «of anaplastic»
The first study by Bell and colleagues re-analyzed outcomes from a prior phase 3 study of anaplastic gliomas using a subset of molecular markers.
http://www.oncologynurseadvisor.com/ Not exact matches
In their bid to find the best combination of therapies to treat anaplastic thyroid cancer (ATC), researchers on Mayo Clinic's Florida campus demonstrated that all histone deacetylase (HDAC) inhibitors are not created equal.
Of the more than 1,600 samples tested, 10.5 % had EGFR sensitizing, 18.8 % EGFR resistance, 13.2 % KRAS, and 2 % EML4 - ALK (anaplastic lymphoma kinase) mutations.
Some patients with non-small cell lung cancer (NSCLC) have changes in the anaplastic lymphoma kinase (ALK) gene, which can drive the development of their cancer.
«Patients with non-small cell lung cancer (NSCLC) should receive front line therapy with the anaplastic lymphoma kinase (ALK) inhibitor crizotinib,» said lead author Professor Giorgio Scagliotti, head of the Department of Oncology, University of Turin, Italy.
The advent of therapies directed at tumors with mutations in epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), and B - Raf proto - oncogene (BRAF) genes over the past decade have dramatically changed outcomes, he says.
The tumors studied fell into the broad category of high - grade gliomas: diffuse intrinsic pontine glioma, which strikes school - aged children; pediatric cortical glioblastoma, which affects primarily teens and young adults; anaplastic oligodendroglioma, which affects young adults; and glioblastoma multiforme, which affects older adults.
Anaplastic, plasmablastic, and plasmacytic plasmacytomas of mice: relationships to human plasma cell neoplasms and late - stage differentiation of normal B cells.
Brentuximab vedotin was previously approved by the FDA to treat cHL after relapse, cHL after stem cell transplant when a patient is at a high risk of relapse or progression, systemic anaplastic large cell lymphoma (ALCL) after failure of other treatment, and primary cutaneous ALCL after failure of other treatment.
Activation of Mammalian Target of Rapamycin Signaling Pathway Contributes to Tumor Cell Survival in Anaplastic Lymphoma Kinase — Positive Anaplastic Large Cell Lymphoma
Anaplastic large cell lymphoma (ALCL) is an aggressive form of malignant lymphoma of T / null lineage (1).
Anaplastic lymphoma kinase (ALK)-- positive anaplastic large cell lymphoma (ALCL) frequently carries the t (2; 5)(p23; q35) resulting in aberrant expression of chimeric nucleophosAnaplastic lymphoma kinase (ALK)-- positive anaplastic large cell lymphoma (ALCL) frequently carries the t (2; 5)(p23; q35) resulting in aberrant expression of chimeric nucleophosanaplastic large cell lymphoma (ALCL) frequently carries the t (2; 5)(p23; q35) resulting in aberrant expression of chimeric nucleophosmin - ALK.
A subset of ALCL tumors carries chromosomal aberrations involving the anaplastic lymphoma kinase (alk) gene on chromosome 2p23 resulting in ALK overexpression (2).
Targeting MYC as a Therapeutic Intervention for Anaplastic Thyroid Cancer JCEM March 28, 2017 Keisuke Enomoto, Xuguang Zhu, Sunmi Park, Li Zhao, Yuelin J. Zhu, Mark C. Willingham, Jun Qi, John A. Copland, Paul Meltzer, and Sheue - yann Cheng Anaplastic thyroid cancer (ATC) is one of the most aggressive cancers in humans.
In this interview we discuss the link between breast implants and anaplastic large - cell lymphoma, a rare type of T - cell lymphoma.
TEMODAR is indicated for the treatment of adult patients with refractory anaplastic astrocytoma, i.e., patients who have experienced disease progression on a drug regimen containing nitrosourea and procarbazine.
ONC201 demonstrated (GI50 1 - 8 µM) dose - and time - dependent efficacy in acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML), chronic lymphocytic leukemia (CLL), diffuse large B - cell lymphoma (DLBCL), mantle cell lymphoma (MCL), Burkitt's lymphoma, anaplastic large cell lymphoma (ALCL), cutaneous T - cell lymphoma (CTCL), Hodgkin's lymphoma (nodular sclerosis) and multiple myeloma (MM) cell lines including cells resistant to standard of care (dexamethasone in MM) and primary samples.
Anaplastic carcinoma makes up 2 % of all thyroid cancer cases, and was made famous by the 2012 bestseller The Fault In Our Stars ($ 11; amazon.com)(the main character, a teen with this cancer, was played by Shailene Woodley in the movie).
American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
According to the National Cancer Institute at the National Institutes of Health, there is an estimated 60,220 new cases and 1,850 deaths from thyroid cancer in the United States alone.5 Thyroid cancer is classified into four different types: papillary thyroid cancer, follicular thyroid cancer, medullary thyroid cancer, and anaplastic thyroid cancer.
Anaplastic thyroid cancer is a type of thyroid cancer that is rare and aggressive.
On February 1st, after my first day at my new job, I was diagnosed with Lymphoma (anaplastic large cell alk negative; one of the rarer types of non-Hodgkin's lymphoma).
These are anaplastic (undifferentiated cell, characteristic of malignant neoplasms) round cells that no longer resemble macrophages (white blood cells within tissues, produced by the division of monocytes) and display multiple criteria for malignancy.
In general, squamous cell and anaplastic carcinomas have a higher rate of metastasis than adenocarcinomas.
She was presented to our Oncology department at VRCC in May of 2009, with a biopsy confirmed diagnosis of an aggressive sweat gland tumor (anaplastic apocrine gland adenocarcinoma) of the skin of the right chest wall.
Anaplastic: Anaplastic thyroid cancer is the most serious type of thyroid cancer and is very hard to recover from.