Sentences with phrase «of antibody against the virus»

The results come in the form of positive (there are protective levels of the antibody against the virus) or negative (there are not protective levels of antibody against the virus in the blood).

So when these in - clinic tests are performed properly, it means that a positive test result demonstrates the dog or cat does have protective levels of antibody against the virus.

Not exact matches

One of these, IgA, which is present in highest amounts in the first few days of life, contains many antibodies against viruses, bacteria and other disease - causing organisms.

That development is important because a T cell response will likely confer longer - term protection than current inoculations do and defend against a variety of flu strains (because T cells would be on the lookout for several different features of the flu virus whereas antibodies would be primarily focused on the shape of a specific strain).

Previous research has suggested that antibodies — immune system proteins that can attack viruses — in a mother might be less effective against certain genetic variants of HIV - 1 in her body, thereby allowing for transmission of resistant viruses to her infant at delivery.

The team started with a naturally occurring antibody that reacted only against limited number of types of dengue virus.

These antibodies protect against certain strains of influenza virus in the vaccine, but may not provide thorough protection against other strains of flu that may be present.

Data from in vivo mouse models indicate that delivery of the DMAb sequence for the influenza A-targeted monoclonal antibody protected against lethal doses of two very different, clinically relevant influenza A viruses.

In a first for any animal, including humans, four cows injected with a type of HIV protein rapidly produced powerful antibodies against the virus, researchers report.

Smider and colleagues took serum — blood with the cells removed, leaving antibodies behind — from four immunized cows and tested it against different types of HIV virus in a test tube.

The theory that antibodies protective against one type of dengue can collude with a different type of the virus to make a second infection worse was proposed in the 1960s.

One reason vaccines using weakened flu virus are not used in the elderly is that they have been exposed to many strains of flu virus over the years and have more antibodies in the nasal tract, which can inhibit the weakened flu virus from infecting and stimulating the immune response necessary to protect against the virus.

This one - two punch protected the test subjects against influenza A viruses that had emerged in 1934 and 2007, and other experiments showed that the antibodies it generated successfully neutralized a wide variety of flu strains.

A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed against the own virus strain, but also against different sub-types of HIV that circulate worldwide.

Just over a year ago, the same team of South African researchers reported in Nature Medicine (also part of the Nature group of journals) on their discovery relating to two other KwaZulu - Natal women, that a shift in the position of one sugar molecule on the surface of the virus led to the development of broadly neutralizing antibodies against HIV.

In July in Science Immunology, McDermott and colleagues reported that the stalk antibodies against group 2 of the A viruses appear to be more broadly effective than those against group 1 viruses.

Not only were the mice protected from lethal doses of flu virus, but the protection was also in large part due to the absence of familiar antibodies against the head, the researchers found.

Pregnant women with a previous history of herpes simplex virus type 1 (HSV - 1) infection maintain active antibodies against the virus, and researchers have found that this protection can pass to the nervous systems of their offspring.

The researchers believe this difference in B cell distribution among those with uncontrolled HIV adds to a list of reasons most people do not make effective antibodies against the virus.

In a series of laboratory experiments, the researchers found that antibodies against HSV - 1 remain in the trigeminal ganglion (a group of nerve cells that receives signals from the eyes and face and is a key site of HSV infection) long after active virus infection is cleared, and that these maternal antibodies can travel to the fetal trigeminal ganglia.

The new «trivalent» vaccine induces antibodies against three different parts of the virus, including two components that normally help HSV2 evade immune attack.

The x-ray crystallographer at the Scripps Research Institute in San Diego, California, is leading an international effort to develop a potent mix of monoclonal antibodies against the virus, some of which have already shown promise in animals.

Because survivors of an Ebola infection would typically have produced effective antibodies against the virus (otherwise they wouldn't have survived), transfusions of their blood into a newly infected individual may help that person survive the often fatal disease.

La Jolla Institute scientist Shane Crotty, Ph.D., a respected vaccine researcher and member of one of the nation's top AIDS vaccine consortiums, showed that certain helper T cells are important for triggering a strong antibody response against HIV, the virus that causes AIDS.

-- Hyperimmune globulin, prepared by purifying and concentrating plasma of immunized animals or previously infected humans with high titers (concentrations) of neutralizing antibody against Ebola virus, which have been shown to be protective in monkeys but are not currently available and would not be expected before mid-2015.

That's why researchers are engineering plants to produce key parts of viruses and bacteria, in the hope that the human body will take them for invaders and start producing antibodies against the organisms.

Currently, seasonal flu vaccines are designed to induce high levels of protective antibodies against hemagglutinin (HA), a protein found on the surface of the influenza virus that enables the virus to enter a human cell and initiate infection.

More than 35 % of the cottonmouths had antibodies against the virus, and 22.2 % had bits of the virus's RNA in their blood.

Two of three vaccinated dromedary camels — known carriers of the MERS virus — produced neutralizing antibodies against the virus.

All three of the exposed animals not only survived the virus but developed high amounts of protective antibodies against it, likely protecting them against future exposures (although the research team has not yet explored how long that immunity lasts).

In years past dolphins had apparently built up some level of antibody defense against the virus so that contracting it did not always lead to death.

For example, the most advanced therapy — ZMappTM, a cocktail of three monoclonal antibodies — is specific for Ebola virus (formerly known as «Ebola Zaire»), but doesn't work against two related ebolaviruses (Sudan virus and Bundibugyo virus) that have also caused major outbreaks.

The flu vaccine works by exposing the body to parts of inactivated flu from the three major different types of flu that infect humans, prompting the immune system to develop antibodies against these viruses.

The antibodies against H7subtype viruses exhibit «remarkable neutralizing potency,» and thus may represent a new way to protect people who have been exposed to or infected by avian influenza, they reported today in The Journal of Clinical Investigation.

Instead of working through antibody - mediated immunity, Liang says successful prophylactic vaccines against the virus might have to work through cell - mediated immunity, which means immune cells are taught to attack infected cells.

In studies at Canada's National Microbiology Laboratory in Winnipeg, nine out of 19 patients had traces of the SARS coronavirus's RNA; four out of seven patients also had antibodies against the virus.

«Previous studies have shown that antibody preparations that protect against low doses of virus may be ineffective against higher doses,» they warn.

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The study, published in Scientific Reports, demonstrated that animals injected with synthetic DNA engineered to encode a specific neutralizing antibody against the dengue virus were capable of producing the exact antibodies necessary to protect against disease, without the need for standard antigen - based vaccination.

People with higher levels of antibodies against the stem portion of the influenza virus hemagglutinin (HA) protein have less viral shedding when they get the flu, but do not have fewer or less severe signs of illness, according to a new study published in mBio.

Six months later, the subjects returned and the scientists drew blood and measured the levels of antibodies against the flu virus.

«This study provides evidence that a single dose of an antibody stimulates patients» immune response, enabling them to make new or better antibodies against the virus,» explains Till Schoofs, a postdoctoral fellow and one of the study's first authors.

Last month, a small fragment of the virus's genome turned up in a Saudi Arabian bat, and retired racing camels in Oman were found to carry antibodies against the virus.

However, «past studies performed with viruses containing higher populations of 7U viruses using other MAbs did not protect [non-human primates] against Ebola - Zaire, whereas studies using different antibodies containing high populations of 8U did.

An article published on June 26th in PLOS Pathogens now reports that a mini antibody called 3D8 scFv can degrade (or chew up) viral DNA and RNA regardless of specific sequences and protect mammalian cells and genetically manipulated mice against different viruses.

These so - called broadly neutralizing antibodies (bNAbs) do little to help the people who produce them, but their existence indicates that mutations have created an increasingly diverse population of the virus, which in turn has pushed the immune system to evolve a response that is both more potent and works against more variants.

When the researchers exposed chickens to lethal doses of the avian influenza virus and the Newcastle virus, birds inoculated with the recombinant vaccine produced antibodies against both viruses, offering protection against both diseases.

A major goal of HIV - 1 vaccine development is to identify immunogens capable of inducing protective titers of broadly neutralizing antibodies (bNAbs) against circulating, neutralization - resistant (tier 2) viruses.

In the new study, CDC's Nicholas Komar and Kasen Riemersma — who's now at the University of California, Davis — used existing blood samples from white - tailed deer, raccoons, moose, and coyotes collected between 2009 and 2014 in 19 states, both in the center of the lone star tick's range and its periphery, and tested them for antibodies against the Heartland virus.

«As eliciting a highly diverse immune response may be favorable to providing protection against incredibly diverse HIV - 1 variants in global circulation,» the researchers conclude that their study «supports further investigations of the molecular and functional characteristics of the virus - antibody interplay in superinfected individuals, as superinfection may provide insight to the development of a diverse Nab response with multiple epitope specificities.»