397 patients who were 18 — 65 years of age, had a diagnosis of schizophrenia or schizoaffective disorder according to DSM - IV criteria, had required intensive psychiatric treatment within 24 months before study entry, had received a stable dose
of antipsychotic medication for ≥ 30 days before study entry, had resided at the same address for ≥ 30 days before study entry, and were judged clinically stable by the principal investigator.
After a 7 week stay at the psychiatric ward, the hospital released our daughter into our care, but she was on very high
doses of antipsychotic medications and was not able to function on her own.
The researchers examined more than 400 people with PDP, who were taking part in a separate trial, to assess the
impact of antipsychotic medications on their overall health and wellbeing.
With a concern about inappropriate
prescribing of antipsychotic medications to children, 31 states have implemented prior authorization policies for atypical antipsychotic prescribing, mostly within the past 5 years, and with most states applying their policies to children younger than 7 years of age, according to a study in the March 3 issue of JAMA.
According to the researchers, more research is needed to determine if off - label use
of antipsychotic medications yields substantial clinical benefit and to identify how doctors decide to prescribe these drugs for non-FDA approved conditions.
In order to establish whether symptoms had improved following the first
course of antipsychotic medication, responses to treatment were measured at the beginning of the study and 12 weeks later.
Although several studies have compared the efficacy and tolerability of different
dosages of antipsychotic medications for psychotic relapses, this has been addressed in few relapse prevention studies, and none compared various dosages of haloperidol.
People with long - term schizophrenia are three times more likely than the general population to have diabetes, something which has previously been attributed to poor diet and exercise habits in this group, as well as the use
of antipsychotic medication.
«Interestingly, the use
of antipsychotic medication was not associated with longitudinal differences in the course of weight gain, nor was the type or availability of antipsychotics,» said Strassnig.
Since 2003,
some of the antipsychotic medications have been approved by the FDA for the treatment of other conditions, including irritability in autism and treatment - resistant depression.
Multivariate logistic regression analyses indicated that past adolescent conduct disorder, being younger and male, symptoms of Akathisia (movement disorder, most often develops as a side effect
of antipsychotic medications), and particularly drug abuse increase the risk for CJS involvement.