The researchers now have plans to conduct further work to explore the safety and effectiveness
of the approach in vivo and in advanced lung tumor mouse models.
Building on strong drug discovery and early clinical development expertise, iTeos intends to demonstrate the clinical efficacy
of its approach in proof of concept trials, on its own or in co-development with a partner.
Of note, the study by Belshe et al. 2 further shows the potential applicability
of this approach in healthy persons older than 60 years of age, despite the fact that the responses in this group were generally somewhat less robust than those in younger adults.
To test the safety
of the approach in humans, the team treated 10 LINCL patients ranging in age from 3 to 10 years, starting in 2004.
A team of researchers around PD Dr. Hubert Dinse of the NeuralPlasticity Lab at the Institute for Neuroinformatics, Prof. Dr. Martin Tegenthoff, Director of the Neurological Clinic, and Prof. Dr. Christoph Maier, senior physician of the Department for Pain Medicine, both at the Bergmannsheil University Clinic, have now investigated the effectiveness
of this approach in pain patients.
In a research collaboration with Sydney Water, the team has demonstrated the success
of the approach in laboratory tests on filtered water from the Nepean Water Filtration Plant in western Sydney, and is working to scale up the new technology.
The current method of prescribing medication now sometimes includes a pharmacogenomic approach, but researchers recognize the limitation
of this approach in predicting a response to a particular drug and dosage combination.
The party then enacted as part of its rules this year the almost unheard
of approach in New York of allowing unaffiliated voters to participate in its primaries.
They said: «Though we do not doubt Your Excellency's bona fide concerns for the peaceful resolution of the crises, we nevertheless have reservations as to the efficacy
of this approach in ensuring lasting solutions.
Any country would be surprised with this type
of approach in funding.»
«Though we do not doubt Your Excellency's bona fide concerns for the peaceful resolution of the crises, we nevertheless have reservations as to the efficacy
of this approach in ensuring lasting solutions,» the letter said.
The governor said the differences
of approach in addressing the incident yesterday was a case of «semantics,» adding:
To be sure, adoption
of the approach in the West is in its infant stage, so to speak.
There's a great article about this type
of approach in a recent Bicycle magazine — an ADD college student who rides a bike in order to not take medication and be able to study.
The 32 - year - old World Cup winner was the subject
of an approach in January from Chelsea, managed by his former Juventus boss Antonio Conte.
I have specifically criticized Ronald L. Williams's article as paradigmatic
of this approach in «The Possibilities for Process Christology,» Encounter 35/4 (Autumn 1974), 281 - 94, esp.
Indeed the past thirty years, and the past twenty - three years since the publication of Fr Purnell's work have seen the virtual complete failure
of this approach in catechetics and in religious education in our schools.
So we need a new kind
of approach in our preaching of the gospel; and this approach depends upon a new way of envisaging the gospel itself.
Most firms stopped on cold calling because they don't know how to handle this kind
of approach in generating qualified sales leads.
John and Jesus did both, though
both of them approached it in different ways.
«There are two types
of approaches in life.
We need varieties
of approaches in attack instead of blaming our strikers.
This foundational course provides a broad overview
of approaches in applied mathematics, covering both deterministic and stochastic methods, with an emphasis on ecological questions, and is taken by general mathematics students who wish to obtain an introduction to graduate - level applied math, as well as by our students who are specifically interested in mathematical biology.
«
Of the approaches in our experiments, soaking in water at 90?
«You need a portfolio
of approaches in managing water security,» says James Cameron, acting CEO of the National Water Commission, the Canberra - based government agency in charge of the country's water reform agenda.
That is why we have used a combination
of approaches in this investigation.
The Dellabona / Casorati lab investigates T cell responses in tumor immunosurveillance and immunotherapy, by combining a variety
of approaches in pre-clinical and clinical models.
There have been new papers taking
each of these approaches in recent months.
Not exact matches
Johnson is proposing a unique
approach to combat the depressingly repetitive, dehumanizing experiences that black people and other people
of color too frequently experience
in retail spaces.
For years, Harvard — once a top performer among universities, but
in recent years an also - ran — pursued a «hybrid»
approach, employing multiple teams
of in - house investment managers as well many outside managers.
In the U.S., unemployment is below the U.S. Federal Reserve's (Fed's) estimate of the «natural» rate that is consistent with stable wage growth, while unemployment rates in many other developed economies are rapidly approaching a similar poin
In the U.S., unemployment is below the U.S. Federal Reserve's (Fed's) estimate
of the «natural» rate that is consistent with stable wage growth, while unemployment rates
in many other developed economies are rapidly approaching a similar poin
in many other developed economies are rapidly
approaching a similar point.
In the beginning that
approach worked out well, but eventually they had to start paying for those endorsements and the size
of the company didn't match up.
The current government has already flagged they don't understand the needs
of the tech industry through the NBN policy decisions they have made and I genuinely hope this doesn't further extend to a «do nothing»
approach in the upcoming budget and throughout the rest
of their term.
To ensure that the Government delivers on its commitments, a new results and delivery
approach will be implemented that includes the establishment
of the Cabinet Committee on Agenda, Results and Communications, chaired by the Prime Minister, and a Results and Delivery Unit, housed
in the Privy Council Office.
The country is infamous not just for imprisoning journalists but for its totalitarian
approach to media
in general, including the suppression
of social media through censorship
of Twitter (TWTR), Facebook (FB) and YouTube.
And
in conversations with a few
of the key players at HMS and the filmmakers, I gained insight into how your small business should
approach this kind
of opportunity.
In an August 2010 thread on a forum discussing ways to improve the privacy
of Bitcoin, one commenter under the alias «Insti» proposed zero knowledge proofs as one potential
approach, though the author worried that they might be «theoretically impossible.»
But the possibility that we could have one million unemployed truck drivers
in 10 years, we don't
approach those problems with the same sense
of urgency.
One
of my most basic
approaches in business is to copy successful people.
I should also note a thrust
of my Leadership and the Environment keynote is that although I support science, education, innovation, and the
approaches to reducing pollution, resource depletion, overpopulation, global warming, and our other environmental problems, I believe we need leadership
in the style
of Martin Luther King Junior, Nelson Mandela, Vaclav Havel, Mohandas Gandhi, and so on.
«
In the financial industry, there's been a lot of debate, post — financial crisis, around different approaches to risk and gender difference,» says Brenda Trenowden, global head of funds at ANZ Banking Group in London and a member of the steering committee of the 30 % Club, which works to get more women on corporate board
In the financial industry, there's been a lot
of debate, post — financial crisis, around different
approaches to risk and gender difference,» says Brenda Trenowden, global head
of funds at ANZ Banking Group
in London and a member of the steering committee of the 30 % Club, which works to get more women on corporate board
in London and a member
of the steering committee
of the 30 % Club, which works to get more women on corporate boards.
If you run a small business (or a large business), being a part
of a documentary series might sound like a marketing, exposure, and credibility - enhancing dream... but only if you
approach the project
in the right way, and with the right people.
But she said that the number
of hats she was wearing
in each situation was draining, and she wanted to take a more focused
approach to entrepreneurship.
Their
approach, he explains, is to use data to give patients and providers more information and reduce the amount
of medical care people consume, or,
in the lingo
of the industry, «utilization.»
Social innovation group takes a DIY
approach to encouraging entrepreneurs
in absence
of significant state support.
Trump's name shows up
in filings
of less than 14 %
of all companies, but the stakes are much higher for firms that have bet on the federal government taking a hands - off
approach to marijuana policy.
«Because
of our emphasis on the long - term, we may make decisions and weigh tradeoffs differently than some companies... We will continue to make investment decisions
in light
of long - term market leadership considerations rather than short - term profitability considerations or short - term Wall Street reactions... We aren't so bold as to claim that the above is the «right» investment philosophy, but it's ours, and we would be remiss if we weren't clear
in the
approach we have taken and will continue to take.»
The unpredictability
of the Trump administration
in the U.S. may further encourage the Canadian government to take a more measured
approach to tax policy.
This «Super Slow» form
of resistance training was popularized by inventor Ken Hutchins who conducted the «Nautilus Osteoporosis Study» and found the slow - moving controlled exercise
approach to be effective
in building bone density
in elderly women with osteoporosis.
In the past, when people
of color were treated with indignity and disdain for simply existing, most responses from company leaders involved an
approach of firing an employee, a feeble apology, and business as usual once the event faded from the headlines.