Disruption of the biosynthesis
of aromatic amino acids (these are essential amino acids not produced in your body that must be supplied via your diet)
We found that this is directly attributable to parasite breakdown
of aromatic amino acids, such as tryptophan, in the host, and to the excretion of the novel by - products into the bloodstream.»
Glyphosate works by stopping an enzyme called EPSPS that is crucial for production
of aromatic amino acids in the shikimic acid pathway.
Not exact matches
White's group is working on catalysts that can modify a wider range
of amino acids, particularly those with electron - rich
aromatic functionality, which compete with the carbon - hydrogen bonds for oxidation using the current catalyst.
Called indole -3-acetic
acid, or IAA for short, in technical language, it is a derivative
of tryptophan, an
aromatic amino acid.
The disinfectant was able to inactivate extracts
of various enzymes because it is highly reactive with sulfur - containing and
aromatic amino acids.
Work previously published in the Proceedings
of the National Academy
of Sciences (doi: 10.1073 / pnas.0906112107) from Lee's collaborator Arul Jayaraman, professor in the Artie McFerrin Department
of Chemical Engineering at Texas A&M University who holds a master's from Tufts School
of Engineering, had already demonstrated that indole, a bacterial metabolite derived from the
aromatic amino acid tryptophan, caused an anti-inflammatory response in the gut and increased resistance to pathogen colonization that could lead to infection
The research team focused on
aromatic amino acids (AAAs) because their metabolites are involved in many
of the more than 2,400 distinct reactions expressed in the microbiota as a whole.
Structure - activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration
of amino acid residues
of pentapeptides by substitutions
of several
aromatic amino acids.
Starting from compound 16, several derivatives, in which the D - Phe (4 - F) 1 moiety was replaced by various
aromatic amino acids, while maintaining the same configuration
of [D - Phe (4 - F) 1, L - Arg2] fragment, have been synthesized.
A parallel study was performed focusing on the exploration
of amino acid residues
of cyclic pentapeptides by systematic substitutions
of various
aromatic amino acid residues [62].
p.Tyr89Cys is an
aromatic polar neutral to polar neutral
amino acid substitution, at a highly conserved position and lies within the functionally important ETS - domain
of the protein.
Schon, M. R., Heil, W., Lemmens, H. P., Padval, D., Matthes, M., Puhl, G., Neuhaus, P., and Hammer, C. Xenogeneic, extracorporeal liver perfusion in primates improves the ratio
of branched - chain
amino acids to
aromatic amino acids (Fischer's ratio).
Blomstrand, E. and Newsholme, E. A. Effect
of branched - chain
amino acid supplementation on the exercise - induced change in
aromatic amino acid concentration in human muscle.
Phenylalanine is one
of the three
aromatic amino acids, which include the other two, Tyrosine and Tryptophan.
It breaks down proteins to form peptides and
amino acids with preferential cleavage
of peptide bonds, where the carbonyl group is from either a basic
amino acid or an
aromatic amino acid.
The best source for humans is from the meat
of other animals, though it can be difficult to get enough tryptophan into the brain, as it is the least abundant
amino acid in muscle tissue, and it has to compete with all the other more abundant
aromatic amino acids for the
aromatic amino acid transporter.
The allergy is an immune response to the saliva (or components
of the saliva — including antigens,
amino acids,
aromatic compounds, polypeptides, and phosphorus) injected by fleas when they bite your cat or dog.