Sentences with phrase «of autologous stem cell»

Natesan S, Wrice NL, Baer DG, et al., Debrided Skin as a Source of Autologous Stem Cells for Wound Repair.

Not exact matches

«If we win, the entire regulatory structure for autologous cell processing, with or without culture, will be rewritten such that any physician using good practices and treating patients responsibly can use stem cells as part of his or her medical practice,» he says.

The study, «Lenalidomide (LEN) maintenance (MNTC) after high - dose melphalan and autologous stem cell transplant (ASCT) in multiple myeloma (MM): A meta - analysis (MA) of overall survival (OS),» is ASCO 2016 abstract no. 8001 and will be discussed during the Hematologic Malignancies — Plasma Cell Dyscrasia oral abstract session Friday, Juncell transplant (ASCT) in multiple myeloma (MM): A meta - analysis (MA) of overall survival (OS),» is ASCO 2016 abstract no. 8001 and will be discussed during the Hematologic Malignancies — Plasma Cell Dyscrasia oral abstract session Friday, JunCell Dyscrasia oral abstract session Friday, June 3.

«Lenalidomide maintenance following autologous stem cell transplant can now be considered a standard of care for people with multiple myeloma,» says Dr. McCarthy, senior author on the meta - analysis and Principal Investigator of the U.S. study, CALGB (Alliance) 100104.

Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).

In particular, they allege that news of the investigations, which came to light this past April, cost them millions of dollars by derailing a deal to sell their stem cell company, Autologous / Progenital, and took them out of the running for lucrative faculty positions.

«Previous studies have shown that a threshold percentage of limbal stem cells (which are responsible for replenishing the cornea) is required for successful corneal autologous therapy,» says co-first author Tom Bongiorno, a graduate student in bioengineering at Georgia Tech.

The treatment in the current study, called autologous hematopoietic stem cell transplantation (AHSCT), was given to patients with advanced forms of the disease that had failed to respond to other medications.

Pattern of employment and associated factors in long - term lymphoma survivors 10 years after high - dose chemotherapy with autologous stem cell transplantation.

«Autologous stem cell transplant should be standard care for HIV - associated lymphoma: Multicenter, Phase II trial suggests autologous transplant should be standard of care for HIV patients with relapsed / treatment - resistant lymphoAutologous stem cell transplant should be standard care for HIV - associated lymphoma: Multicenter, Phase II trial suggests autologous transplant should be standard of care for HIV patients with relapsed / treatment - resistant lymphoautologous transplant should be standard of care for HIV patients with relapsed / treatment - resistant lymphoma.»

However, these problems associated with histocompatibility may be solved using autologous donor adult stem cells, therapeutic cloning, stem cell banks or more recently by reprogramming of somatic cells with defined factors (e.g. induced pluripotent stem cells).

Although many immunosuppressive strategies have failed, the recent use of autologous hematopoietic stem and progenitor cell (HSPC) transplantation has shown therapeutic promise.

Based on our data, autologous stem cell transplant should be considered the standard of care for patients with HIV - related lymphomas for the same indications and under the same circumstances that we would use it in patients without HIV infection.»

In addition, transgenic autologous hematopoietic stem cells can be successfully transplanted in HIV - infected individuals [18] and several phase I adoptive transfer trials of CD4 + T cells treated with R5 - ZFNs in HIV infected individuals are currently underway.

However, coreceptor - specific ZFNs represent a novel therapeutic approach to recapitulate this success via autologous transplantation of gene - modified hematopoietic stem cells and mature CD4 + T cells.

Vision Loss after Intravitreal Injection of Autologous «Stem Cells» for AMD.

In close collaboration with universities and physicians world - wide, our comprehensive investigational stem cell treatments employ well - targeted combinations of allogeneic human umbilical cord stem cells, autologous bone marrow stem cells, and autologous adipose stem cells for the diseases listed below.

In a previous study by the same group 78, autologous culture - expanded MSC were infused to breast cancer patients to investigate whether MSC would enhance the engraftment of peripheral blood stem cells after myeloablative therapy.

Ed Field currently is the Chief Operating Officer of Cytomedix, Inc. (OTCBB: CMXI), a US - based company that is developing and commercializing autologous regenerative biotherapies that promote healing by harnessing the innate regenerative capacity of platelets and adult stem cells.

For the first time, researchers demonstrate long term success of a cell replacement therapy using autologous induced pluripotent stem cell derivatives

In 2016, the Food and Drug Administration (FDA), the branch of government charged with regulating cellular therapies, took action to address these issues, proposing revised guidelines that could change how stem cells, especially autologous stem cells, are regulated.

Biological markers of Mesenchymal Stromal Cells as Predictors of response to Autologous Stem Cell Transplantation in Patients with Amyotrophic Lateral Sclerosis; an Investigator - Initiated Trial and in Vivo Study.

Around 5 - 10 % of patients with solid tumors who are treated with chemotherapy, radiation or autologous stem cell transplantation develop treatment - related MDS or AML.

In this study, Peterson and colleagues have tried to recapitulate aspects of Brown's treatment using gene editing and autologous stem cell transplant.

The US Food and Drug Administration (FDA) has granted Priority Review designation for tisagenlecleucel (Kymriah), formerly known as CTL019, for treatment of adult patients with relapsed or refractory diffuse large B - cell lymphoma (DLBCL) who are ineligible for, or have relapsed after, autologous stem cell transplant.

Towards the clinical translation of intra-articular injection of MSCs, the group of Kang Sup Yoon at the Seoul National University College of Medicine, Seoul, Korea report on their a proof - of concept phase I / II clinical trial intra-articular injection of autologous adipose tissue derived mesenchymal stem cells (AD MSCs)[6].

Review of «Biological markers of Mesenchymal Stromal Cells as Predictors of response to Autologous Stem Cell Transplantation in Patients with Amyotrophic Lateral Sclerosis; an Investigator - Initiated Trial and in Vivo Study» from Stem Cells by Stuart P. Atkinson

His current focus is on the production of autologous hepatocytes from patient - derived induced pluripotent stem cells (iPSCs).

The therapy from Trinity Clinic Fukuoka involves 10 intravenously administered doses of 200 million autologous adipose tissue - derived mesenchymal stem cells.

Thus, for the specific example you gave of using autologous bone marrow stem cells injected into the brain, this scenario would indeed require full FDA approval as it does not meet the criteria of homologous use, as you said.

Patients receive one of two types of stem cell - based transplants: autologous, in which a patient donates and receives back his / her own stem cells; or allogeneic, in which bone marrow - derived stem cells come from a related or unrelated donor whose human leukocyte antigens (HLA) are genetically matched with those of a patient.

I was diagnosed with non-Hodgkin's diffuse B - cell lymphoma on Aug. 14, 2015, and since then, I have undergone three rounds of chemotherapy, 22 radiation treatments and an autologous stem cell transplant.

High - Dose Chemotherapy Plus Transplant Not Recommended for DLBCL: The results of an Italian study report that treatment of high - risk diffuse large B - cell lymphoma (DLBCL) with abbreviated course of rituximab dose - dense chemotherapy plus high - dose cytarabine, mitoxantrone, and dexamethasone (R - MAD) plus carmustine, etoposide, cytarabine, and melphalan (BEAM) plus autologous stem cell transplantation compared with a full course of rituximab dose - dense chemotherapy did not improve overall survival.

That happened right before my autologous stem cell transplant, after I'd done one more round of chemotherapy before my stem cells were harvested.

The technique involves replacing a mutated copy of the gene with a healthy copy in stem cells isolated from the patient, which are then transfused back into the body — a process known as autologous stem cell transplantation.

This is the «show reel» of Dr Haluk Deda, a Turkish neurosurgeon who is setting up shop in Dubai, where he plans to offer autologous stem cell transplants to treat chronic spinal cord injuries and ALS, a condition with no known cure that generally leads to death within three to five years of diagnosis.

Additionally, the head of a prominent human embryonic stem cells firm (Geron) has publicly questioned the viability of commercialized therapeutic applications of autologous hiPSCs due to the regulatory requirements imposed by the US Food and Drug Administration [7].

Unmatched performance — high transfection efficiency & cell viability in primary cells Fully scalable — from R&D to the clinic without reoptimization Safe — non-viral cell engineering in closed, sterile, computer - controlled environment Cell loading flexibility — mRNA, gRNA, siRNA, DNA, proteins, cell lysates, and small molecules into autologous or allogenic immune, stem / progenitor, or somatic cells Regulatory ease — Master File designation with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - macell viability in primary cells Fully scalable — from R&D to the clinic without reoptimization Safe — non-viral cell engineering in closed, sterile, computer - controlled environment Cell loading flexibility — mRNA, gRNA, siRNA, DNA, proteins, cell lysates, and small molecules into autologous or allogenic immune, stem / progenitor, or somatic cells Regulatory ease — Master File designation with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - macell engineering in closed, sterile, computer - controlled environment Cell loading flexibility — mRNA, gRNA, siRNA, DNA, proteins, cell lysates, and small molecules into autologous or allogenic immune, stem / progenitor, or somatic cells Regulatory ease — Master File designation with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - maCell loading flexibility — mRNA, gRNA, siRNA, DNA, proteins, cell lysates, and small molecules into autologous or allogenic immune, stem / progenitor, or somatic cells Regulatory ease — Master File designation with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - macell lysates, and small molecules into autologous or allogenic immune, stem / progenitor, or somatic cells Regulatory ease — Master File designation with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - marked

Transplants types are categorized by the source of the donor: Autologous transplants: Patients receive their own stem cells.

The strongest challenge to this approach, granting the periodic replenishment of somatic stem - cell pools with autologous but OncoSENS - ready stem cells, has been the possible existence of functions of TERT (telomerase reverse transcriptase — the catalytic subunit of telomerase), other than the lengthening of telomeres itself.

It is an autologous limbal stem cell composite graft, prepared from the limbal biopsy excised from the healthy eye of the patient.

Their research focused on evaluating the safety and efficacy of autologous bone marrow - derived stem cell transplantation in individuals with type 2 diabetes with good glycemic control as well, which emerged as an important aspect in the transplantation group as well as in the non-transplanted group.

Two promising new area for Hashimoto's treatment: the use of the drug low dose naltrexone (LDN) and autologous stem cell transplants.

The other type of therapy is autologous mesenchymal stem cell transplantation.

One type of stem cell transplant, autologous hematopoietic stem cell transplantation, uses stems cells from your own bone marrow, or from external umbilical cord blood.

Autologous Adult Stem Cells are being used to treat many types of chronic pain and degeneration.

We utilize autologous adipose tissue for the source of stem cells.

Title: Transplantation and Tracking of Autologous Epidermal Neural Crest Stem Cells into the Spinal Cord of Dogs with Acute Severe Spinal Cord Injury

Vet - Stem Regenerative Medicine uses a concentrated form of autologous adipose - derived adult stem cells to treat traumatic and degenerative diseases, including bowed tendons, ligament injuries, osteoarthritis, and osteochondral defects in horses, dogs and cStem Regenerative Medicine uses a concentrated form of autologous adipose - derived adult stem cells to treat traumatic and degenerative diseases, including bowed tendons, ligament injuries, osteoarthritis, and osteochondral defects in horses, dogs and cstem cells to treat traumatic and degenerative diseases, including bowed tendons, ligament injuries, osteoarthritis, and osteochondral defects in horses, dogs and cats.

We use autologous fat derived stem cells (also called adult stem cells, mesenchymal stem cells, stromal vascular fraction stem cells...) which are from the pet itself so there is little likelihood of any untoward reaction.