«Laminins function as attractive chemical cues for haptotaxis
of axonal growth cones,» explains NAIST Prof. Naoyuki Inagaki, whose lab studies how forces are generated in the cellular microenvironment to create directed axonal migration.
Not exact matches
Subsequently, the ultrastructure
of mechanically elongated axons was examined to distinguish actual
growth from a redistribution
of axonal components.
Scaling great walls When they both started at Penn, Lee had a project on the effects
of nerve
growth factor on PC12 cells, and Trojanowski was studying
axonal transport and endocytosis.
Failure
of myelin to compensate for larger
axonal diameters suggested a lack
of plasticity during the processes
of myelination and radial
axonal growth.
Radial
axonal growth initiates with myelination, and is dependent upon the C terminus
of neurofilament medium (NF - M).
We report that targeting miR - 181a regulates
axonal growth, and that miR - 181a inhibition may be a novel therapeutic approach for
axonal regeneration
of neurons affected by PD.