As director of the NIMH, Dr. Gordon oversees an extensive research portfolio
of basic and clinical research that aims to transform the understanding and treatment of mental illnesses, paving the way for prevention, recovery, and cure.
«Jim Mullikin is the ideal choice to champion the broad scientific portfolio of the NIH Intramural Sequencing Center, which is one of NHGRI's premiere research assets,» said NHGRI Scientific Director Daniel Kastner, M.D., Ph.D. «Dr. Mullikin brings a comprehensive experiential and academic background to NISC, taking on the wealth
of basic and clinical research initiatives already underway and planning for the genomic contributions that this center will be making well into the future.»
Our radiologists also take part in a variety
of basic and clinical research activities.
Through a powerful integration
of basic and clinical research, we are driving major advances that have an impact on many of today's most devastating diseases.
Identifying microbiota - derived metabolites and understanding their effects on specific host functions could open up new avenues
of basic and clinical research to develop safe, targeted therapies involving molecules that, by definition, constitute the natural chemical makeup of the host.
Not exact matches
Young SL, Mbuya MNN, Chantry CJ, Geubbels EP, Israel - Ballard K, Cohan D, Vosti SA
and Latham MC, Current Knowledge
and Future
Research on Infant Feeding in the Context
of HIV:
Basic,
Clinical, Behavioral,
and Programmatic, Adv. Nutr 2011; 2: 225 — 243, doi: 10.3945 / an.11 0.000224 full pdf + html
Our longstanding dedication to working with industry
and investors is reinforced by the creation
and continual advancement
of infrastructure, technologies
and policies that fully support
basic and clinical research —
and its translation into commercially viable products
and services in health care.
His
basic laboratory
and clinical research focus has been in the area
of neonatal jaundice, with particular reference to its relationship to breastfeeding.
To succeed as a clinician - researcher, a physician - scientist uses his or her mastery
of both
clinical practice
and basic science
research in parallel, often drawing on both skill sets to find advances in the diagnosis, treatment,
and prevention
of human disease.
That priority influences the design
of research questions, Weng notes,
and encourages scientists involved in
basic research, including postdocs, to participate in «very dynamic» collaborations with translational
and clinical groups.
D. degrees train individuals in
clinical and basic research, but translational
research programs strive to integrate these two sides
of medical science by connecting people
and building networks.
This study builds on nearly three decades
of foundational
research led by teams at Nationwide Children's
and Ohio State's Wexner Medical Center
and exemplifies the strong
basic science
and clinical bonds between the two institutions.
«Dr. Bry has used her
clinical training to inform herself
of scientific priorities in both her
basic and applied
research.
At Mayo, some immunologists work on
basic research and others lean more toward the
clinical applications
of immunotherapy.
Because the center is made up
of four diverse divisions (Public Health Sciences,
Basic Sciences,
Clinical Research,
and Human Biology), the talks cover something outside a member's direct area
of expertise most
of the time, which makes for an eager
and enthusiastic audience.
Gaab's interest in working at the intersection
of basic,
clinical,
and education
research was piqued when she was doing her doctoral work in neuroscience, studying how auditory or musical training affects the brain.
The Blueprint is a cooperative effort among 16 NIH institutes, centers,
and offices that supports the development
of new tools, training opportunities,
and other resources to assist neuroscientists in both
basic and clinical research.
Brad Spellberg's
research interests are diverse, ranging from
basic immunology
and vaccinology, to pure
clinical and outcomes
research, to process improvement work related to delivery
of care, focusing on safety net hospitals.
The use
of MRI for
research, rather than diagnostic, purposes is a relatively new development,
and clinical investigators in the imaging community often do not understand the
basic cellular
and neural circuitry issues as well as they should, he says.
Apart from high - quality treatment, the aim
of the SHCS is to conduct integrated multidisciplinary
research in both the
basic and clinical sector.
Thomas Mandrup - Poulsen, professor in medical
research methodology, University of Copenhagen, conducts both basic and clinical diabetes research at the Hagedorn Research Institute and Steno Diabetes
research methodology, University
of Copenhagen, conducts both
basic and clinical diabetes
research at the Hagedorn Research Institute and Steno Diabetes
research at the Hagedorn
Research Institute and Steno Diabetes
Research Institute
and Steno Diabetes Center.
Despite the drawbacks, these programs open the doors to a vast array
of well - funded, cutting - edge, postgraduate possibilities in clinics
and in
basic, disease - oriented,
and clinical research.
«This work is an example
of how integrating
basic science
and clinical care may reveal privileged opportunities for biomedical research,» said Matthew O. Hebb, M.D., Ph.D., FRCSC, a researcher involved in the work from the Departments of Clinical Neurological Sciences (Neurosurgery), Oncology and Otolaryngology at the University of Western Ontario in Ontario,
clinical care may reveal privileged opportunities for biomedical
research,» said Matthew O. Hebb, M.D., Ph.D., FRCSC, a researcher involved in the work from the Departments
of Clinical Neurological Sciences (Neurosurgery), Oncology and Otolaryngology at the University of Western Ontario in Ontario,
Clinical Neurological Sciences (Neurosurgery), Oncology
and Otolaryngology at the University
of Western Ontario in Ontario, Canada.
Just as the alchemists
of old attempted to combine different elements to produce something valuable, the physician - scientist
of today attempts to combine medicine
and basic research to produce something that has
clinical utility.
Although juggling all
of these issues can be demanding
and at times stressful (such as during the recent highly publicized temporary suspension
of clinical research on our campus), working in a
clinical environment has allowed me to develop my interpersonal
and communication skills to a level that I never would have achieved in a purely
basic science setting.
Another area that is becoming increasingly important is the translation
of basic science
research findings into
clinical applications,
and there is a growing need for physician scientists, says Alan Trounson, president
of the California Institute for Regenerative Medicine (CIRM).
Physician - scientists bridge medicine
and research and provide a channel
of communication that is a
basic yet critical component in any disease - oriented or
clinical research endeavor.
«Our study suggests that short height in children is a possible marker
of stroke risk
and suggests these children should pay extra attention to changing or treating modifiable risk factors for stroke throughout life to reduce the chances
of having this disease,» said senior study author Jennifer L. Baker, Ph.D., associate professor in the Center for
Clinical Research and Prevention at Bispebjerg
and Frederiksberg Hospital
and Novo Nordisk Foundation Center for
Basic Metabolic
Research, Faculty
of Health
and Medical Sciences, at the University
of Copenhagen, in Denmark.
Scientists have to be able to hit the ground running, as innovation in the pharmaceutical
and biotechnology industries is a long
and costly process, involving several stages
of basic, applied,
and clinical research,
and often taking up to 15 years to complete.
Back in the US,
and further along the translational pipeline is Doug Lowy,
of the NIH in Bethesda, Maryland, who has already experienced the potential
of harnessing
basic research for
clinical use.
To make that climb a little easier, the National Institutes
of Health (NIH) offers a range
of debt repayment programs for scientists who decide to do
basic,
clinical, or behavioral
research in areas targeted by NIH, such as minority health disparities
and AIDS.
Since the development
of the earliest
clinical hematology analyzers, automated cell counting based on cellular shapes has been a staple technique
of medical
and basic research laboratories.
Research in this area spans several disciplines, from the biochemical study
of basic mechanisms
of alcohol metabolism, to the neuroscience
of dependency, to demographic
and clinical studies on at - risk populations.
The University
of Sheffield's Department
of Oncology
and Metabolism conducts world - class
research from
basic clinical and translational cancer
research to life course
research and basic level biology through to diseases such as diabetes
and osteoporosis.
As such, it provides a means
of moving organoids from
basic research to actual pharmaceutical
and clinical applications in the future.
More recently, reductionism has been counterbalanced by the emergence
of «systems biology,» which I expect to reanimate the crucial link between
basic science,
clinical research,
and medical practice.
► In this week's STM editorial, four German scientists
and administrators proposed reforms aimed at «Moving medicine forward faster,» including «the formation
of multidisciplinary centers, which guarantees a geographical
and organizational proximity
of clinical and basic research.»
Yet the overall conclusion
of these studies is that this success is typically in
basic science,
and not in patient - oriented or
clinical research.
This is the
basic outline
of a randomized control
clinical trial — the gold standard
of medical
research and the basis
of most
of the medical facts we hear from doctors
and read in magazines like this one.
The new generation
of geneticists will need to juggle
basic science, genetics, statistics,
clinical research,
and sometimes even more disciplines.
«This alternative source
of Leydig cells will be
of great significance for
basic research and provides the attractive prospect
of clinical application in the field
of regenerative medicine.»
But the review panel says that scientists should be careful not to make exaggerated claims about the medical impact
of such
research,
and funding organizations should encourage more cooperation between
basic and clinical researchers to make sure experimental results have maximum impact.
Until more epidemiological
and basic research can be conducted to further parse out the associations between PD, cholesterol
and statins, physicians
and scientists should be cautious in promoting health benefits
of statins for PD without a good understanding
of clinical evidence
and potential biological mechanisms, Huang advises.
This example suggests «that almost all
basic science behavioral
research and experimental psychopathology
research would be viewed misleadingly as a
clinical trial,» wrote neuroscientist William Iacono
of the University
of Minnesota in Minneapolis in one
of more than 30 comments expressing concern on the Open Mike blog
of NIH extramural chief Michael Lauer.
In 2003, in «A vision for the future
of genomics
research,» Francis Collins — who was then the director of the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health — and his co-authors encouraged collaboration between basic scientists and clinical scientists, and between life scientists and social scientists, to address the ethical, legal, and social implications of genomic and genetic research and the resulting new techn
research,» Francis Collins — who was then the director
of the National Human Genome
Research Institute (NHGRI), part of the National Institutes of Health — and his co-authors encouraged collaboration between basic scientists and clinical scientists, and between life scientists and social scientists, to address the ethical, legal, and social implications of genomic and genetic research and the resulting new techn
Research Institute (NHGRI), part
of the National Institutes
of Health —
and his co-authors encouraged collaboration between
basic scientists
and clinical scientists,
and between life scientists
and social scientists, to address the ethical, legal,
and social implications
of genomic
and genetic
research and the resulting new techn
research and the resulting new technologies.
Every day for 2 months, she questioned senior
and junior faculty members on the
basic and clinical ends
of the
research spectrum — no small task for someone working 13 - hour days, typically without a break.
Between those two extremes
of basic and applied knowledge lie two nascent, rapidly expanding subfields: translational
research informatics
and clinical research informatics.
Currently, Fotios continues his
research at the interface between
basic science
and clinical medicine as a
clinical lecturer in hepatology at the University
of Cambridge with
clinical commitments in Addenbrooke's Hospital.
Building on findings from
basic brain
research, lab studies
of sleep,
clinical studies
of sleep
and dreams,
and his records
of his own dreams, Hobson explores the mechanisms
and functions
of dreams
and sleep.
Bringing together bench
and bedside is the purpose
of a new institute that aims to become a world - class «translational» cancer
research centre, where the knowledge gained from
basic research is translated into
clinical applications.