This approach aims to push the boundaries of discovery by promoting the translation
of basic research discoveries into therapies and treatment.
Not exact matches
The efficient movement
of basic science
discoveries into clinical applications — often described as «bench to bedside» work — is the goal
of translational
research.
Of approximately 300 staff at the Center for Therapeutic
Research, only nine postdocs and students are conducting basic research; the rest work in drug discovery and deve
Research, only nine postdocs and students are conducting
basic research; the rest work in drug discovery and deve
research; the rest work in drug
discovery and development.
Basic research can be slow and in efficient, and sometimes it's not clear if the effort will be worth the reward
of discovery.
His
research career, peppered with landmark
discoveries that go all the way from uncovering the
basic principles
of how DNA instructs cells to make proteins to unraveling the genetic blueprint
of the puffer fish, is an indelible part
of the history
of molecular biology.
«These
discoveries demonstrate a hypothesis that we had made following a
basic research study we had just carried out in our laboratory, and thus confirm the physiological importance
of the unfolded protein response in the control
of neurogenesis,» says Laurent Nguyen.
Basic scientific
research, conducted at universities in communities across the country, is the smallest slice
of the nation's R&D pie, yet it is the critical spark that ignites
discovery and innovation in the United States.
«These results enable future studies in Alzheimer's and other disease models and highlight the importance
of basic research which precedes drug -
discovery,» says Jaan - Olle Andressoo.
«Doing solid
basic research leads to new
discoveries, which leads to protection
of those technologies in the form
of intellectual property.»
Lydia Villa - Komaroff, a molecular and cellular biologist and co-founding member
of the Society for the Advancement
of Chicanos / Hispanics and Native Americans in Science, underscored the value
of basic research, noting that her work studying strains
of infection - resistant bacteria led to a
discovery that «made it possible to make insulin and other treatments in bacteria.
«While we celebrate the «a ha» moment
of scientific
discovery and invention, such moments are only the point
of initiation for the
basic research required to develop new drugs,» said Dr. Laura McNamee, the lead author
of the paper and a
research associate in Bentley's Center for Integration
of Science and Industry.
Although this
discovery is a result
of basic research, it opens up new avenues in plant breeding.
«Our
discovery is as such
basic research, and PNAS wished to publish it because we have shown the way to change one type
of pump into another type
of pump, which reaches into our innermost understanding
of the membrane pumps.
Some
basic research findings are being translated into new treatments, and with the
discovery of induced pluripotent stem cells in 2006, the field has seen a step - change in biological understanding that will affect the way new drugs are identified and tested and, potentially, the way cells can be generated in the lab.
Basic research in the 1920s laid the foundation for the microelectronics industry
of the 1950s; physicists»
discoveries in the 1950s led to the nanotechnology
of the 1990s.
By conducting
basic research in the same cell lines that will be used in patients, researchers should also be able to speed the translation
of their
discoveries to treatments, says Crook.
«The
discovery of this new antibiotic was an unexpected result
of basic research on HIV proteins,» said senior author Ronald Montelaro, Ph.D., professor and co-director of Pitt's Center for Vaccine Researc
research on HIV proteins,» said senior author Ronald Montelaro, Ph.D., professor and co-director
of Pitt's Center for Vaccine
ResearchResearch (CVR).
He co-led the study with Barbara Kahn, M.D. «Our
discovery came out
of basic research to understand the mechanism underlying type 2 diabetes.»
The chance
discovery of Cas12a's unusual behavior highlights the importance
of basic research, Chen said, since it came from a
basic curiosity about the mechanism Cas12a uses to cleave double - stranded DNA.
This advance in breast cancer
research reflects the mission
of Stem Cell Reports to provide an open - access forum that communicates
basic discoveries in stem cell
research as well as translational and clinical studies.
Our message is that science is a single, unified, long - term enterprise in which
basic science
discoveries, and
research accomplishments
of applied science and engineering, are things to be admired in their own right that also, often unpredictably, lead to better jobs and better lives, new products and new industries.
-- The term «translational
research» means coordination
of basic or applied
research with technical and commercial applications to enable promising
discoveries or inventions to attract investment sufficient for market penetration and diffusion.
The 2013 Albert Lasker
Basic Medical
Research Award honors two scientists for their
discoveries concerning rapid neurotransmitter release, a process that underlies all
of the brain's activities.
Basic research provides the foundation for monumental
discoveries, fosters the development
of ground - breaking technologies and gives us the information we rely on when making important...
As for the Wellcome Trust, it's an unabashed supporter
of basic science, usually through
research grants or infrastructure support to academic scientists, but the charity wanted to better translate
discoveries into health benefits to the developing world.
His
discoveries are now being applied in virtually all areas
of biomedicine — from
basic research to the development
of new therapies.
Even in areas
of basic research, failure to reproduce has put into the bin several potentially path - breaking
discoveries.
Additionally, the Institute's recent alliance with the California Institute for Biomedical
Research (Calibr) adds translational research to its capabilities, enabling a new bench - to - bedside model that will accelerate the translation of basic scientific discoveries into critically - needed new medicines for unmet medica
Research (Calibr) adds translational
research to its capabilities, enabling a new bench - to - bedside model that will accelerate the translation of basic scientific discoveries into critically - needed new medicines for unmet medica
research to its capabilities, enabling a new bench - to - bedside model that will accelerate the translation
of basic scientific
discoveries into critically - needed new medicines for unmet medical needs.
While translational
research has traditionally moved
basic immunology knowledge forward into clinical application, varying clinical presentations
of human immune - related disease processes, as well as variability in therapeutic outcomes, have provided opportunities for
discovery of novel mechanistic hypotheses directly from patients.
Ludwig combines
basic research with the ability to translate its
discoveries and conduct clinical trials to accelerate the development
of new cancer diagnostics and therapies.
Addressing
basic research, clinical diagnostics, drug
discovery, environmental, food and beverage, forensics, and other markets, American Laboratory combines in - depth articles, news, and video to deliver the latest advances in their fields to thousands
of print and online subscribers.
And for the first time since World War II, government funding has fallen to less than half
of all
basic research funding, according to Science magazine, putting pressure on labs to commercialize their
discoveries more quickly.
Our laboratory's translational
research program, is dedicated to turning the
discoveries of basic science, from fields such as molecular science and genetics, into effective treatments for patients.
«Ranging from
basic research in plant molecular sciences through the field application
of new
discoveries, these teams benefit science, Washington agriculture, energy and human health.»
Washington, DC — The Department
of Energy (DOE) has awarded Carnegie $ 10 million over four years for
basic research that could lead to the discovery of new energy materials through its program to support Energy Frontier Research
research that could lead to the
discovery of new energy materials through its program to support Energy Frontier
Research Research Centers.
Hemley remarked: «EFree II will conduct bold, high - risk
discovery science leading to next generation materials needed address a broad range
of unsolved energy problems.We are pleased that the Department
of Energy continues to value both the unique capabilities
of Carnegie and its scientists as well as the institution's long - standing commitments to this exciting area
of basic research.»
This award comes on the heels
of numerous other honors recognizing Dr. Yamanaka and the importance
of his iPS
discovery, including the 2012 Nobel Prize in Physiology or Medicine, the Breakthrough Prize in Life Sciences, the Millennium Technology Prize, the Albert Lasker
Basic Medical
Research Award, the Shaw Prize and the Kyoto Prize for Advanced Technology.
Established to honor its namesake's exceptional leadership in business and philanthropy, the honor is given to an internationally renowned senior Salk scientist who has made extraordinary
discoveries in
basic biomedical
research and has contributed to the direction and vitality
of the Institute.
Washington, D.C. — The Department
of Energy (DOE) has awarded Carnegie $ 10 million over four years for
basic research that could lead to the discovery of new energy materials through its program to support Energy Frontier Research
research that could lead to the
discovery of new energy materials through its program to support Energy Frontier
Research Research Centers.
The RBL, one
of 11 in the country, serves as a valuable shared resource to others in academic, not - for - profit and private sectors for BSL - 3 training,
basic research and translational
discovery efforts.
«This funding will help provide important new opportunities to translate
basic discoveries and leading - edge technologies from UC San Diego's
research laboratories into needed therapies for patients — an effort being spearheaded by our new Drug Discovery Institute,» said Palmer Taylor, PhD, associate vice chancellor for Health Sciences and dean
of the Skaggs School
of Pharmacy and Pharmaceutical Sciences.
According to a release from Dr. Hassan Dihazi, editor in chief, the journal covers all areas
of proteomics including
basic proteomic
research; structural, functional, property, and interaction analysis
of cellular systems, organelles, and protein complexes; and protein expression profiling for the
discovery and validation
of diagnostic and prognostic disease biomarkers.
Your financial support will help us fund important
research programs so that we can move our
basic discoveries more rapidly from the proof -
of - principle stage through translational
research and preclinical testing that leads to human clinical trials.
December 21, 2015 — Noteworthy NIH advances in
basic research include charting human genetic variation across the globe, the
discovery of lymphatic vessels in the central nervous system, and insights into energy - burning fat cells.
3/22/2007 UCSD Cancer Researcher Richard D. Kolodner Honored with Landon - AACR Prize for
Basic Cancer
Research Scientists whose
discoveries have led to fundamental advances in the science and treatment
of cancer are the recipients
of two prestigious international prizes offered by the Kirk A. and Dorothy P. Landon Foundation and the American Association for C...
These tools enable life scientists to analyse components
of living cells at the molecular level which is essential in a wide range
of fields including drug
discovery, diagnostics, and
basic research.
He understood that
basic research rarely brings immediate rewards but he also understood that future generations would come to depend on the
discoveries of science to create a better world.
Continuing its rich history
of discoveries and biomedical breakthroughs, Wistar today is an international leader in
basic biomedical
research in cancer and infectious diseases, with a focus on
discoveries leading to the development
of novel therapies and vaccines.
Researchers at the Sanford Consortium for Regenerative Medicine have broad scientific goals in
basic and preclinical
research, as well as preclinical development
of discoveries.
Hunter's breakthrough, which set the story in motion, was a product
of basic research on a chicken RNA tumor virus: the 1979
discovery of the first tyrosine kinase paved the way for our understanding
of how cells perceive their environment and respond appropriately to growth signals.