Sentences with phrase «of bitter taste receptors»

Behrens and his colleagues Kristina Blank and Wolfgang Meyerhof developed a way to screen which of the bitter taste receptors that saccharin and cyclamate were hitting, to figure out why the combination is more palatable than either one alone.

Not exact matches

Because scientists have discovered that the same receptors that exist on the tongue to taste bitter substances are also found on the smooth muscle of the lungs.

«But as the bacteria multiply, they consume more glucose, removing the sweet taste receptor «brake» and allowing for release of AMPs by the bitter taste receptors.»

«We believe that the complimentary roles of the bitter and sweet taste receptors in these SCCs keeps upper airway colonizing bacteria at optimal levels during periods of relative health,» Cohen says.

What's more, the action of the bitter receptors is blocked when sweet taste receptors are stimulated by sugars such as glucose.

Now, scientists from the Perelman School of Medicine at the University of Pennsylvania reveal that the release of AMPs is partially controlled by bitter taste receptors in the upper airway on a cell previously identified in animals and only recently in humans known as solitary chemosensory cells (SCCs).

The teams at AFB International and Integral Molecular studied the behavior of two different cat bitter taste receptors in cell - based experiments, investigating their responsiveness to bitter compounds, and comparing these to the human versions of these receptors.

The team also found that probenecid, a known inhibitor of human bitter taste receptors, also worked on both cat taste receptors, preventing stimulation when in the presence of PTC, aloin and denatonium.

TAS2R38 is a bitter taste receptor in humans of which some people have «supertaster» variants that give them an extreme sensitivity to bitter compounds, explaining some people's strong aversions to broccoli and brussels sprouts.

«Here we show that the bitterness of sampled ethanol varies with genetic differences in bitter taste receptor genes, which suggests a likely mechanism to explain previously reported relationships between these gene variants and alcohol intake.»

In the first study to show that the sensations from sampled alcohol vary as a function of genetics, researchers focused on three chemosensory genes — two bitter - taste receptor genes known as TAS2R13 and TAS2R38 and a burn receptor gene, TRPV1.

«In our research, we show that when people taste alcohol in the laboratory, the amount of bitterness they experience differs, and these differences are related to which version of a bitter receptor gene the individual has.»

a) The Eye in your Thigh: a patch of skin cells on the leg that can distinguish between bright and dark conditions, perhaps to help regulate the body clock b) The Ear in your Rear: nerves in the buttocks attuned to infrasound vibrations of between 10 and 25 hertz, perhaps to warn of approaching predators or thunderstorms c) The Nose in your Toes: scent - detecting sebaceous glands on the feet whose purpose is unclear d) The Tongue in your Lung: taste - bud - like receptors that detect bitter substances and dilate or restrict the airways accordingly

al., tested the hypothesis that herbivores — and their plant diets — have evolved to have greater number of Tas2r bitter taste receptor genes in their genomes than omnivores or carnivores.

Unlike sweet taste, which has only one or perhaps two different receptor types, the number of functional bitter taste receptor types — those that are able to respond to bitter compounds — varies greatly across species.

To do this, they incorporated the gene sequence of each receptor into cultured cells and then probed the cells to determine if they were activated by one or more of 25 different bitter - tasting chemicals.

AMP has no bitterness of its own, but when put in foods, Margolskee and his colleagues discovered, it attaches to bitter - taste receptors.

As effective as it is, AMP may not be able to dampen every type of bitter taste, because it probably doesn't attach to all 30 bitter - taste receptors.

In 2000 Zuker and others found some 30 different kinds of genes that code for bitter - taste receptors.

«In our research, we show that when people taste alcohol in the laboratory, the amount of bitterness they experience differs, and these differences are related to which variant of a bitter receptor gene the individual has.»

They first discovered that a bitter taste receptor known as T2R38 plays a role in people's susceptibility to an infection known as chronic rhinosinusitis (CRS)-- a disease that affects nearly 35 million Americans and is a huge driver of drug resistance.

Blends of non-caloric sweeteners saccharin and cyclamate show reduced off - taste due to TAS2R bitter receptor inhibition.

In our GI tract, bitter taste receptors can simultaneously promote the absorption of «safe» bitter compounds and the excretion of toxic ones, thereby preventing overexposure to the many low - grade food - borne toxins we eat every day.

The mechanism by which they stimulate boosted digestive capacity is wondrously simple: the bitter taste receptors on our tongue and other areas of the mouth register that a bitter compound has entered your body.

The book covers everything from tone of voice (high = playful, low = serious) to the reason bitter spray won't stop inappropriate chomping (bitterness receptors are on the back of dogs» tongues, so they won't taste it on a shoe).