Since dogs have such a dramatic capacity to elevate leukocyte numbers, it is often difficult to differentiate between leukemia and what is termed a leukemoid reaction — a strong and persistent leukocytosis without the presence
of blast cells.
The project included the construction of a new Distribution Center, a 3 - story building for the Boning Area and Executive Offices, a single - story office for Evisceration operations and construction
of Blast Cells for freezing deboned turkey meat.
Not exact matches
Instead
of having readers come to your website to check out your latest, you
blast it directly to their
cell phone inboxes.
Researchers
blasted rats with full - body doses
of RF radiation (mostly at higher levels than those associated with
cell phones) from the time they were born until they were two years old for nine hours a day.
Business unit manager Tom Hutton has empowered a group
of hourly workers to purchase grit
blast equipment for two
cells.
Those considering joining the rest
of civilization in owning a
cell phone, and those thinking about replacing the
blasted thing when their two - year agreement finally runs out must address the...
The popular brew is filled with compounds called catechins that
blast belly flab by triggering the release
of fat from fat
cells, then speeding the liver's capacity for turning that fat into energy.
After a few days, they divided the clusters into individual
cells, a small percentage
of which grew into so - called
blast colonies
of up to 400 million
cells, the team reports in Nature Methods.
The group is now pursuing studies that couple the mechanical forces
of a
blast, or pressure wave, to the activation
of chemical - signaling pathways in neural
cells.
The reaction begins when an antibody activates a component
of the immune system known as a mast
cell, which then
blasts out a barrage
of chemicals.
Working in Morrison's Neurotrauma and Repair Laboratory at Columbia Engineering, the team developed a
blast injury model using a shock tube and custom - designed sample receiver to simulate a primary
blast event and applied it to an isolated, living model
of the BBB that consisted
of brain endothelial
cells.
In a bid to progress beyond the shotgun approach to fighting cancer —
blasting malignant
cells with toxic chemicals or radiation, which kills surrounding healthy
cells in the process — researchers at the Harvard - MIT Division
of Health Sciences and Technology (HST) are using nanotechnology to develop seek - and - destroy models to zero in on and dismantle tumors without damaging nearby normal tissue.
After all, it's much easier to run a computer program than to grow
cells,
blast them with a compound, and incubate them before getting any sort
of results.
Then the
blast of radiation emitted by the radioisotope would destroy the... tumor
cells nearby.»
And Nobelist Günter Blobel, a German - born
cell biologist at Rockefeller University in New York City, also
blasted the plan in an interview in Der Spiegel magazine, saying that the concept reminds him
of inflexible Soviet - style planning.
But throughout this process the full force
of the laser
blasts even
cells whose light is not in focus for the detector.
Leukemia stem
cells promote an aggressive, therapy - resistant form
of the disease called
blast crisis.
Self - renewal
of blast crisis chronic myeloid leukemia
cells was reduced by approximately 40 percent when treated with the small molecule, called 8 - Aza, as compared to untreated
cells.
Instead
of using some fancy virus, why not just
blast genes into
cells with a gun?
When
blasted with 10 Gy
of irradiation — enough to wipe out all blood stem
cells in the bone marrow
of normal mice — mutant mice that were unable to fully activate p53 experienced only a modest blood count drop.
Although it did not eradicate CML
cells, it did greatly limit the growth
of the tumor clone and decreased the risk
of the feared «
blast crisis».
Other projects that use stem
cells include the development
of cell therapies to improve functional recovery after compartment syndrome, a condition associated with
blast injuries that can cause tissue death and amputation.
Allogeneic Sibling Donor Peripheral Blood Stem
Cells Transplantation With Myeloablative Conditioning for Chronic Myeloid Leukemia in
Blast Crisis - Successful Treatment Despite Severe Phase
of the Disease
Fernando Fierro Becker (Ehninger, TUD)-- «Definition
of molecular pathways with importance for the interaction
of leukemic
blasts with mesenchymal stem
cells» (2008)
In a third
of MDS cases, over time, very immature bone marrow
cells called
blasts may increase in number and fill the bone marrow, displacing the normal red and white blood
cells and platelets that are produced there.
At an experimental mine at the Missouri University
of S&T in Rolla, scientists are setting off explosives around lab mice and
cell cultures to study how exposure to
blasts in combat damage the brains
of military personnel.
Blast cells are the immature white blood
cells that become abnormal and accumulate in the bone marrow and blood in cases
of leukemia.
Arndt, C., von Bonin, M., Cartellieri, M., Feldmann, A., Koristka, S., Michalk, I., Stamova, S., Bornhäuser, M., Ehninger, G. and Bachmann, M. Redirection
of T
cells with a first fully humanized bispecific CD33 - CD3 antibody efficiently eliminates AML
blasts without harming hematopoietic stem
cells.Leukemia, doi: 10.1038 / leu.2013.18.
Elevated numbers
of circulating CD34 (+)
cells were found in p.P214L and p.Y401N carriers, and two patients from different families suffered from refractory anemia with excess
blasts, while one patient from a third family was successfully treated for acute myeloid leukemia.
Myelosuppression is a well - established side effect
of current AML therapies, with prolonged events leading to an increased risk
of infections and death.44 Consequently, therapies that preferentially kill leukemic
cells over normal bone marrow
cells are urgently required, and the overexpression
of CD123 on AML leukemic stem
cells and
blasts compared with normal hematopoietic
cells contributes to its attractiveness as a therapeutic target in this disease.6, 45 However, severe myelosuppression and myeloablation have emerged for some investigational CD123 - targeted treatment modalities.
The cytotoxicities
of IMGN632 and X-ADC were first assessed in a panel
of AML
cell lines, which expressed CD123 at levels similar to AML
blast cells (ABC values, 1100 - 13000) and encompassed a variety
of poor prognostic markers (Table 1).
As little children our
cells produce plenty
of antioxidants, like running a water faucet full
blast.
That means that within 15 minutes
of drinking your green juice your body receives a
blast of liquid sunshine that nourishes your trillions
of cells and restores your immune system.
The upgraded equivalent to a free Christian dating
cell phone app is a
blast and we are getting great feedback from many
of our recent members!
Adults who would sooner use diminishing brain -
cell capacity to store more pertinent information can tell you who teaches Muggle Studies at Hogwarts, the uses
of gillyweed and the difference between a grindylow and a
blast - ended skrewt.
to
blast her way out
of a
cell.
The armoured SUV delivers lateral protection against up to 15 kg
of Trinitrotoluene (TNT)
blasts and against DM51 grenade explosions from beneath the floor and above the roof, thanks to the specially developed six - part armoured passenger core
cell made out
of super strength steel.
Thrombocytopenia (drop in
cells that help blood clot) and the presence
of blast or immature
cells in circulation represents the weakened
cell strength.
Once you reach the top, you're semi-satisfied as you take a deep breath
of that city air, close your eyes, and listen to the sounds
of cell phones, cars, and music
blasting.
It's just like
blast processing, the power
of the
cell or «it only does everything» slogan.
For anyone who enjoys a high level
of realism in their stealth games, or any game for that matter, Splinter
Cell will be a
blast to play.
«That's one
of the reasons why I think we're seeing the fish, the corals and a lot
of the invertebrates dying as quickly as they are — their
cells are basically
blasting out, coming down,» described Richmond.