Sentences with phrase «of bleeding disorder»

In some cases careful evaluation of the type of bleeding disorder present is necessary to raise the suspicion of hemangiosarcoma.
Dogs that have less than 35 % of the normal amount of vWf generally have mild to moderate signs of a bleeding disorder.
Infectious canine hepatitis can be spread through feces, saliva, urine, blood and nasal discharge and it results in both infection of the liver and the establishment of a bleeding disorder.
If you have any kind of bleeding disorder, make sure to tell your doctor to avoid complications from having blood drawn.
• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study
Then we must understand the social problems that hemophiliacs have faced for years because of their bleeding disorder.
Potential subjects were accepted into the study if they had none of the following conditions: severe or symptomatic cardiac disease or hypertension; history of bleeding disorders; chronic history of gastric, intestinal, liver, pancreatic, or renal disease; any portion of the stomach or the intestine removed (other than an appendectomy); history of intestinal obstruction, malabsorption, or use of antacid drugs; cancer (active or use of medications for a history of cancer treatment within the past 5 y); history of chronic alcoholism; a convulsive disorder; or abnormal results in screening blood or urine samples.
A heterogeneous group of bleeding disorders.
Approach to the diagnosis of bleeding disorders in the dog and cat.
Researchers will develop an assay to measure canine thrombopoietin (TPO), a bone marrow growth factor, to improve the diagnosis and treatment of bleeding disorders in dogs with immune platelet defects.

Not exact matches

The Food and Drug Administration (FDA) has given Alnylam Pharmaceuticals the green light to relaunch clinical trials of its treatment for the bleeding disorder hemophilia after pausing the studies after a patient death.
In early September, Alnylam stopped giving doses of its fitusiran drug for a rare bleeding disorder to patients enrolled in clinical studies after the death of a patient.
Caution is advised in people with bleeding disorders or in those taking drugs that may increase the risk of bleeding.
Other causes of low milk supply include thyroid disorders, pieces of retained placenta, which would likely be accompanied by abnormal postpartum bleeding, polycystic ovary syndrome, which involves an imbalance of sex hormones, and Sjogren's syndrome, an autoimmune disease.
Babies with Jacobsen's experience a multitude of symptoms, including delayed development, cognitive impairment, behavioral issues, distinctive facial features, feeding difficulties, and almost all have Paris - Trousseau syndrome, a bleeding disorder.
According to Blumenfeld, other babies who need it include babies born via C - section, babies born with forceps or vacuum assistance, babies who had an internal fetal scalp monitor, babies born with any visible bruising or bleeding, babies who are being circumcised or have other upcoming surgeries, if you pushed for more than four hours, and if there is any family history of blood clotting disorders.
Much of her clinical management in the perinatal period has focused on the following: 1) women with a history of childhood sexual abuse and its effects on childbearing; 2) methods to alleviate clinical symptoms of pregnancy such as premature labor, hyperemesis gravidarum, bleeding; and the psychological issues of anxiety and depression; 3) attachment disorders; 4) helping women through events of traumatic birth and loss; 5) postpartum mood disorders; and 6) methods of pain relief in labor with self - hypnosis.
Your baby has a condition that affects the strength of his or her bones, such as osteogenesis imperfecta, or has a bleeding disorder, such as hemophilia
When the body fails to restock, life - threatening forms of anemia, lethal infections or serious bleeding disorders can emerge.
There is an especially strong link between psychiatric disorders and complications during gestation or birth, such as prenatal bleeding, low oxygen or malnutrition of the mother during pregnancy.
A new class of synthetic platelet - like particles could augment natural blood clotting for the emergency treatment of traumatic injuries — and potentially offer doctors a new option for curbing surgical bleeding and addressing certain blood clotting disorders without the need for transfusions of natural platelets.
«For a patient with insufficient platelets due to bleeding or an inherited disorder, physicians often have to resort to platelet transfusions, which can be difficult to obtain,» said Dr. Wilbur Lam, another of the paper's co-authors and a physician in the Aflac Cancer and Blood Disorders Center at Children's Healthcare of Atlanta and the Department of Pediatrics at the Emory University School of Medicine.
One thing I found that was interesting and important was that a lot of people with grid had idiopathic thrombocytopenic purpura, a bleeding disorder.
«If you can prevent antibody formation in the first place, by finding some way of producing immunological tolerance that gets around that type of protocol, that would be a major advantage,» says David Lillicrap, a clinician and researcher who specializes in bleeding disorders at Queen's University in Kingston, Ontario, Canada.
Shire CEO Flemming Ornskov - who has a large conventional haemophilia business and is also chasing Biomarin and Spark in hunting a cure for the bleeding disorder - sees both the opportunities and the difficulties of gene therapy.
Researchers are reporting the highest and most sustained levels to date of an essential blood - clotting factor IX in patients with the inherited bleeding disorder hemophilia B.
Hemophilia A is an inherited bleeding disorder caused by a deficiency of functioning factor VIII (FVIII), a protein essential to clotting.
Thanks to a breakthrough led by researchers in the Cockrell School of Engineering at The University of Texas at Austin, treatment for hemophilia can now be administered via a biodegradable system, a capsule, giving people affected by the hereditary bleeding disorder hope for a less expensive, less painful treatment option than conventional injections or infusions.
ASH is alarmed about the opioid crisis; however, it is concerned about potential adverse effects that policy changes could have on the administration of necessary and appropriate pain medicine for patients with hematologic conditions such as sickle cell disease (SCD), blood cancers, and other bleeding disorders.
His group described the natural history of Lowe syndrome, alkaptonuria, autosomal recessive polycystic kidney disease, Chediak - Higashi disease, GNE myopathy, and Hermansky - Pudlak syndrome (HPS), a disorder of oculocutaneous albinism, bleeding, and pulmonary fibrosis.
A vector developed and manufactured at St. Jude had transformed the lives of young men with this inherited bleeding disorder.
A rare inherited disorder that has been identified in about 400 people worldwide, HPS is mainly characterized by decreased pigmentation (ocular or cutaneous albinism) and a lack of platelet dense bodies that causes bleeding problems.
Congenital amegakaryocytic thrombocytopenia (CAMT) is a rare, inherited disorder characterized by a severely low number of megakaryocytes, a type of bone marrow cell that makes platelets that are important for clotting and preventing bleeding.
Osteogenesis imperfecta (OI) is a rare inherited disorder of the connective tissue with many reports on its association with bleeding diatheses.
The risk: Garlic's blood - thinning properties may increase risk of bleeding associated with warfarin, a blood thinning drug commonly prescribed to people with heart - rhythm disorders and to people who have had heart attacks or heart - valve replacements, as well as aspirin.
Reportedly, it has been used in the treatment of a number of health conditions which include brittle bone, hair, teeth and nails, white spots on nails, gingivitis, tonsillitis, inflammation of the mucous membranes of the mouth, rheumatic disorders, edema, osteoarthritis, diabetes, acne, wounds, itchiness, rashes, burns, frostbite, chilblains, athlete's foot, cracked and tired feet, drawing out pus from boils and carbuncles, ulcers, fistulas, herpes simplex, dyspepsia (impaired digestion), gastrointestinal conditions, cardiovascular diseases, respiratory tract infections, bronchitis, fever, malaria, bladder problems, urinary tract infection, bed wetting in children, kidney stones (nephrolithiasis), prostate problems, hemorrhoids, muscle cramps, tumors, broken bones, fractures, sprains, nose bleed and other heavy bleeding.
Some of the first signs of vitamin D deficiency include tooth decay and bleeding gums but if this issue goes unaddressed for a prolonged period of time it can lead to digestive, immune system, and brain disorders.
If you have a bleeding disorder or are taking blood thinners or other medications, consult with your doctor before incorporating large amounts of flaxseeds into the diet (89, 90).
Therefore, individuals with bleeding disorders or who are taking any type of medication that inhibits clotting should not take nattokinase.
Individuals who have bleeding disorders or low blood pressure should limit their consumption of celery, since it can interact with certain medications.
It has been suggested that those taking anticoagulants or have a bleeding disorder avoid doses greater than 3 grams daily due to a possible increased risk of bleeding.
You should not use RADIESSE ® or RADIESSE ® (+) if you have an allergy to any component of the product, if you have a history of severe allergies, if you have a bleeding disorder, or if you are pregnant or breastfeeding.
Doctors don't recommend intake of safflower oil to people with bleeding disorders, people who are about to undergo surgery etc..
According to Natural Medicines Comprehensive Database, whey may case low blood glucose levels (hypoglycemia) in individuals with diabetes mellitus and increase the risk of bleeding in individuals with bleeding disorders [58].
Do not use if you are pregnant or breastfeeding, or if you have a bleeding disorder, excess stomach acid, oesophageal reflux, duodenal ulcers, or an allergy to reishi mushroom, echinacea, or any other member of the daisy family.
It also has blood thinning effects, and may increase the risk of abnormal bleeding in people with a bleeding disorder or taking anticoagulant medications.29 Frankincense essential oil is also not recommended for pregnant women and nursing moms, as it acts as an emenagogue and may induce menstruation, which may be dangerous for an unborn fetus.30
«Some animals can experience bleeding disorders or coagulopathies, those are the kind of things, even once we get the immediate symptoms under control, that can linger, and we have to monitor that as you go forward,» Shirley said.
There are many other causes of a red eye: uveitis, orbital disease, bleeding disorders, trauma, luxated lens, etc..
The wide range of transfusion needs might include: combating illness or disease, treating an acute blood volume loss and preventative measures in routine surgeries for dogs with bleeding disorders.
Treatment for the bleeding disorders and aggressive supportive care also prolong the life of patients with hemangiosarcoma.
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