Diagnosis
of blood vessel disease is difficult and often relies on finding tumors in other parts of the body.
Not exact matches
It creates a biological response, Murthy says, that leads to chronic inflammation, damaged tissue and
blood vessels, and an increased risk
of heart
disease, arthritis and diabetes.
In
diseases such as malaria and sickle cell
disease, red
blood cells break down, with harmful effects on the rest
of the body — particularly the lining
of small
blood vessels.
It's also super healthy as it's rich in
disease - fighting flavonoids, as well as being full
of magnesium, which works to relax
blood vessels to improve
blood flow and nutrient delivery.
About Kawasaki
Disease: KD is a serious illness characterized by inflammation
of blood vessels throughout the body that primarily affects young children and infants.
Cardiac anatomy consists
of veins and
blood vessels, so a diet that is high in saturated fats and artery clogging foods is a direct cause
of cardiac
diseases and problems during pregnancy, labor and delivery.
Studies have shown that regular consumption
of cocoa may reduce heart
disease risk, help raise good cholesterol, and possibly reverse
blood vessel damage in people with diabetes.
Another serious health concern to watch out for is Kawasaki
disease, which is a rare condition that occurs in children and involves inflammation
of the
blood vessels.
It has been noted that an injury to a person's
blood vessels in their brain may actually dramatically alter the progression as well as onset
of Alzheimer's
disease.
This small
blood vessel change may provide a new therapeutic target to alter the progression
of the
disease.
Interestingly, as many as nine
of the genes have been previously associated with some vascular
disease and four more are known to be involved in the regulation
of vascular tone, supporting the importance
of blood vessels in migraine attacks.
«The main value
of our research is the pinpointing
of the importance
of endothelin - 1 and
blood vessel constriction to multiple vascular
diseases,» says senior author Sekar Kathiresan, a cardiologist at the Broad Institute
of MIT and Harvard University.
Two protein molecules that fit together as lock and key seem to promote the abnormal formation
of blood vessels in joints affected by rheumatoid arthritis, according to researchers at the University
of Illinois at Chicago College
of Medicine, who found that the substances are present at higher levels in the joints
of patients affected by the
disease.
To find out, the researchers injected a cloned telomerase gene into cultured cells from retina, skin, and
blood vessels, all
of which are associated with degenerative, aging - related
diseases.
A major obstacle to improving treatment for the 3,470 cases
of the
disease expected in the United States this year is the
blood - brain barrier, the name given to the tight fit
of cells that make up the
blood vessels in the brain.
Earlier studies have demonstrated that cocoa flavanol intake improves the elasticity
of blood vessels and lowers
blood pressure — but, for the most part, these investigations have focused on high - risk individuals like smokers and people that have already been diagnosed with conditions like hypertension and coronary heart
disease.
To look for the
vessels, Dr. Reich's team used MRI to scan the brains
of five healthy volunteers who had been injected with gadobutrol, a magnetic dye typically used to visualize brain
blood vessels damaged by
diseases, such as multiple sclerosis or cancer.
Understanding this new mechanism
of cardiovascular
disease could lead to the development
of new therapies to treat individuals who suffer from heart and
blood vessel ailments due to these mutations,» explained corresponding author Kenneth Walsh, PhD, professor
of medicine at BUSM.
In
blood diseases such as essential thrombocythemia, too many platelets can lead to clogging
of the
blood vessels, causing clots, heart attack or strokes.
Oxidative stress, inflammation and insulin resistance affect the inner linings
of blood vessels, and are associated with the development
of atherosclerosis, the
disease process that underlies heart
disease and causes the arteries to become narrowed.
A University
of Connecticut study suggests that resveratrol helps stave off heart
disease, and another study suggests that antioxidants like those found in red wine protect
blood vessels from premature damage.
New research published in Diabetologia (the journal
of the European Association for the Study
of Diabetes) shows that age (or age at diagnosis) and duration
of diabetes
disease are linked to the risk
of death and marcovascular complications (those in larger
blood vessels), whereas only diabetes duration is linked to the risk
of microvascular complications (in smaller
blood vessels such as those in the eyes).
Some heart
disease patients may not be able to grow new
blood vessels around blocked arteries because they can't make enough
of a vital protein, according to a report in the latest issue
of Circulation.
Metabolic syndrome is a group
of risk factors — high
blood pressure, high
blood sugar, unhealthy cholesterol levels and abdominal fat — that double the risk
of blood vessel and heart
disease, which can lead to heart attacks and strokes.
Although such abnormal tau clusters are found in brain
diseases including Alzheimer's, their location in CTE is unique — near small
blood vessels, and most often near the bottom
of sulci, the deep folds in the brain's cortex.
High levels
of low - density lipoproteins (LDL — the «bad cholesterol») and triglycerides, a type
of blood fat, are associated with an increased risk
of heart and
blood vessel diseases.
Image courtesy
of iStockphoto / adventtr More than 382,000 people with kidney
disease in the U.S. are on dialysis, a painful procedure that can wreak havoc on
blood vessels due to constant jabs from large needles.
A close look at the characteristic plaques
of scar tissue that lend the
disease its name shows that they typically cluster around
blood vessels.
The concept
of tailoring drugs to regulate and treat abnormal brain
blood vessels is a novel treatment strategy and offers great potential to complement existing treatments
of this debilitating
disease.»
In the U.S., one in every four deaths is a result
of heart
disease, which includes a range
of conditions from arrhythmias, or abnormal heart rhythms, to defects, as well as
blood vessel diseases, more commonly known as cardiovascular
diseases.
These conditions are associated with high
blood sugar, which can damage the
vessels that supply
blood to vital organs and can also increase the risk
of heart
disease and stroke.
Excessive or uncontrolled inflammation can actually make injuries worse and contribute to
disease in a couple
of different ways — by activating cell death processes, clogging and rupturing
blood vessels and producing toxic molecules like free radicals.
Tissues outside
of the bones don't naturally calcify, yet mineralization
of organs, including the heart,
blood vessels, and kidneys, occurs with age and is exacerbated in people with diabetes or kidney
disease.
The most common diabetic eye
disease and a leading cause
of blindness is diabetic retinopathy, which is caused by elevated
blood sugar levels damaging the
blood vessels of the retina and affects approximately 7.7 million Americans.
«We need more research to better understand how to help people who have had adversity in childhood prevent or delay the development
of heart and
blood vessel diseases.»
Not all children who grow up facing adversity develop
diseases of the heart and
blood vessels, a finding that suggests the existence
of a range
of biological, environmental, cultural and social factors that may help reduce risk and prevent
disease development.
Milton Schiffenbauer
of Pace University in New York, US, says that by protecting against this damage, polyphenols may reduce the
blood vessel inflammation thought to promote cardiovascular
disease.
These risk factors raise the likelihood
of developing heart and
blood vessel diseases and conditions in adulthood, including coronary artery
disease, heart attacks, strokes, high
blood pressure, obesity and type 2 diabetes.
The research, which provides an update for 2014 on the burden
of cardiovascular
disease (CVD) in Europe, shows that death rates from CVD (
diseases of the heart and
blood vessels) vary enormously.
However, at least one
of the genetic risk - factors for Alzheimer's
disease may cause these
blood vessels to lose some
of their integrity, which could allow bacteria to enter and colonize the brain.
A major contributor to these cardiovascular
diseases is clogged
blood vessels (atherosclerosis), which result from the buildup
of fatty deposits or plaque.
To demonstrate the potential for treating lung
disease, the researchers used the nanoparticles to block two genes that have been implicated in lung cancer — VEGF receptor 1 and Dll4, which promote the growth
of blood vessels that feed tumors.
They focused on three different types
of PVD: arterial
disease in the lower extremities, called peripheral artery
disease; carotid artery stenosis, which is blockage in the carotid arteries, the major
blood vessels in the neck that supply
blood to the brain, neck and face; and abdominal aortic aneurysm, an enlargement
of the lower aorta, the major
blood vessel that supplies
blood to the body.
We will continue to investigate how it guides
blood vessel growth, with the ultimate aim
of tapping on its potential as a target to address human cardiovascular
diseases.»
A recent study by researchers at the University
of Missouri School
of Medicine has shown that a protein inhibitor drug prevents these blockages, and could be a new therapeutic approach to prevent heart attack, stroke and other
diseases caused by blocked
blood vessels.
Their studies indicate that the two conditions common in sickle cell
disease, dramatically increase red
blood cells» adhesion to the lining
of blood vessels walls and the debilitating pain crises that can result.
«The discovery
of ferroelectricity in
blood vessel walls adds an important dimension to the biophysical properties
of blood vessel wall, which could lead to the development
of new methods in prevention and treatment
of cardiovascular
diseases,» Liu and collaborators write.
Endothelial dysfunction (low
blood vessel reactivity) is considered an early indicator
of cardiovascular
disease risk.
Low levels
of both oxygen and the powerful
blood vessel dilator nitric oxide appear to have an unfortunate synergy for patients with sickle cell
disease, researchers report.
In the less common, wet form
of the
disease, rogue
blood vessels escape normal growth control and leak fluid into the macula, the area at the center
of the retina that enables a person to see fine detail.