Sentences with phrase «of blood vessel lining»

The Texas Heart Institute reports that a person who exercises vigorously and regularly has lower levels of circulating stress - related hormones, which helps improve the health of the blood vessel lining.

Many people with angiosarcoma, a rare and aggressive cancer of the blood vessel lining, survived for only about six months beyond diagnosis.

In cultured human cells and in rabbits with implanted stents, Finn and colleagues showed that metformin augmented the effect of mTOR inhibitors on regrowth of the blood vessel lining.

A study combining tumor cells from patients with breast cancer with a laboratory model of blood vessel lining provides the most compelling evidence so far that a specific trio of cells is required for the spread of breast cancer.

Once these alarm signals reach the surfaces of blood vessels lining the brain, the microglia produce a neurotoxic molecule called interleukin - 1 beta.

Not exact matches

In diseases such as malaria and sickle cell disease, red blood cells break down, with harmful effects on the rest of the body — particularly the lining of small blood vessels.

Cranberries have anti-inflammatory properties, which can reduce the risk of inflammation in blood vessel linings (that means a healthier cardiovascular system) and in the colon and large intestine (leading to a healthier digestive system.)

Cholesterol is carried in the blood and is infused into the cells lining the blood vessels, says Prof. Seneviratne dealing with the chemistry of the human body.

Infant nasal congestion is due to the thickening of the tissue lining of the nose by the inflammation of blood vessels.

The blood vessels shrink in the lining of the nose by decongestants.

During pregnancy, the lining of your uterus thickens and its blood vessels enlarge to provide nourishment to the fetus.

Due to the invasion of the endometrium lining which is rich in blood vessels, bleeding may occur.

Blood Transfusions During Pregnancy Home / Pregnancy Concerns / Blood Transfusions During Pregnancy A blood transfusion is a frequently performed procedure where you receive blood through an intravenous (IV) line into one of your blood vesBlood Transfusions During Pregnancy Home / Pregnancy Concerns / Blood Transfusions During Pregnancy A blood transfusion is a frequently performed procedure where you receive blood through an intravenous (IV) line into one of your blood vesBlood Transfusions During Pregnancy A blood transfusion is a frequently performed procedure where you receive blood through an intravenous (IV) line into one of your blood vesblood transfusion is a frequently performed procedure where you receive blood through an intravenous (IV) line into one of your blood vesblood through an intravenous (IV) line into one of your blood vesblood vessels.

The Weill Cornell researchers» process was more direct: Four transcription factors prompted adult mouse endothelial cells, which line the inside of blood vessels, to turn into HSCs.

Compared with unheated mice, the animals with the faux fever had twice as many white blood cells migrating out of the blood vessels and into the lymph tissue that lines the skin and gut, which is where they need to be to attack incoming pathogens.

It is a smart filter at that: The cells lining the brain's blood vessels can build extra proteins for grabbing glucose if the brain needs a boost and can also destroy some of the proteins to dial the flow back down.

Oxidative stress, inflammation and insulin resistance affect the inner linings of blood vessels, and are associated with the development of atherosclerosis, the disease process that underlies heart disease and causes the arteries to become narrowed.

In experiments conducted on human lung endothelial cells and in mice, the researchers showed that NS1 caused permeability of the endothelium, which lines the walls of blood and lymph vessels.

Epithelial cells form tissue layers that cover our skin and the inner surfaces of most of our internal organs, while endothelial cells line the adjacent blood - transporting vessels and capillaries that support their functions.

In their latest study, Guarente and his colleagues decided to explore the role of sirtuins in endothelial cells, which line the inside of blood vessels.

Luster's team hopes to further investigate the characteristics of joints that underlie the critical role of C5a in initiating type III hypersensitivity and whether specific molecules expressed on endothelial cells lining joints play a role in transporting C5a and chemokines from the joint space into adjacent blood vessels.

An enduring mystery of atherosclerosis — the blockage of arteries that can lead to heart attack and stroke — is why T cells flock to atherosclerotic lesions, sites of inflammation lining blood vessels.

Current thinking regarding type III hypersensitivity is that immune cells within tissues sense the presence of these immune complexes (ICs) through specific receptor molecules and release inflammatory factors called cytokines that activate the endothelial cells lining adjacent blood vessels to promote the recruitment of neutrophils.

In earlier studies involving animal models and human cancer cell lines, researchers found that breast cancer spreads when three specific cells are in direct contact: an endothelial cell (a type of cell that lines the blood vessels), a perivascular macrophage (a type of immune cell found near blood vessels), and a tumor cell that produces high levels of Mena, a protein that enhances a cancer cell's ability to spread.

His experiments revealed the cells that became rhabdomyosarcoma were not muscle cells, but were immature cells that would mature into cells lining the inner surface of blood vessels.

The endothelium is the innermost lining of all blood vessels that interacts with circulating blood.

In experiments with muscle cells from the lining of blood vessels, the researchers found that a sudden mechanical force flips a genetic switch in these cells, making them more likely to contract.

In the current study, the researchers report that NOTCH1 acts like a sensor on the endothelial cells — the cells that line the valve and vessels — detecting blood flow outside of the cell and transmitting information to a network of genes inside the cell.

The researchers then differentiated the iPS cells into endothelial cells, which line the interior of the heart and blood vessels, before transplantation.

To determine whether endothelial cells — the cells that line the interior surface of blood vessels — directly influence breast cancer cell growth, they then created unique organotypic models of lung and bone marrow microvascular niches, in which endothelial cells formed blood vessel - like structures in culture as they would in the original organ.

In the chamber, tubes about the thickness of a human hair were lined with endothelial cells as in natural blood vessels.

Using a powerful imaging technique that allowed the scientists to track the presence and movement of parasites in living tissues, the researchers found that Toxoplasma infects the brain's endothelial cells, which line blood vessels, reproduces inside of them, and then moves on to invade the central nervous system.

The inner cell layer that lines vessels, known as the endothelium, is present in all the blood vessels of the body.

More complex protein drugs ameliorate this problem, but they less readily disperse throughout the body because the more bulky molecules have a harder time passing through blood vessels, the linings of the digestive tract and other barriers.

Their studies indicate that the two conditions common in sickle cell disease, dramatically increase red blood cells» adhesion to the lining of blood vessels walls and the debilitating pain crises that can result.

«Endothelial cells make up the inner lining of blood vessels,» said William Durante, Ph.D., professor of medical pharmacology and physiology at the MU School of Medicine and lead author of the study.

But statins do much more than lower LDL — they affect the function of the lining of our blood vessels and reduce some markers of inflammation, for instance.

The EMT is a biological process wherein epithelial cells (cells that line the cavities and surfaces of blood vessels and organs) become mesenchymal (skeletal) stem cells that can move throughout the body and differentiate into a variety of cell types.

The research indicates that early onset of menopausal symptoms is associated with dysfunction of the endothelium, which is the lining of blood vessels.

The toxicity of chokeberry extract on normal blood vessel lining cells was tested and found to have no effects up to the highest levels used (50 ug / ml), suggesting that the cell death effect is happening in a way other than through preventing new blood vessel formation (anti-angiogenesis), a process that is important in cancer cell growth.

Cardiovascular disease in these young patients develops as vulnerable cells lining the interior of major arteries (vessels that carry blood away from the heart) accumulate the toxic protein and die.

Norepinephrine is recommended as the first - line vasopressor (a drug that constricts [narrows] blood vessels, increasing blood pressure) for treatment of hypotension (abnormally low blood pressure) due to septic shock.

One of biology's great mysteries is the blood - brain barrier, which lines blood vessels in the brain.

The study, published in Proceedings of the National Academy of Sciences, found that rod - shaped nanoparticles — or nanorods — as opposed to spherical nanoparticles, appear to adhere more effectively to the surface of endothelial cells that line the inside of blood vessels.

It both promotes angiogenesis within the tumor and increased the migration of endothelial cells, which form the inner lining of blood vessels.

«Up to now, the Tie2 receptor has only been known in endothelial cells that line the inside of blood vessels,» Milde said.

Instead of dispensing ink, Organovo's bioprinter uses two robotic tips to deposit globs of cells — in this case, endothelial cells that line blood - vessel walls, smooth muscle cells that regulate vessel dilation and contraction, and structural fibroblast cells.

Among other effects, immune cells disrupt the function of the endothelial layer, the lining of the blood vessels, counteracting «all the good things that the endothelial cells produce,» says physiologist Brett Mitchell of Texas A&M College of Medicine in College Station.

A specific lung - targeting molecule is attached to the carrier's surface and the steriod, dexamethasone, an anti-inflammatory, is loaded into the nanogel, which then binds to lung endothelial cells lining the inside wall of the blood vessels where it rapidly delivers the drug.

In an effort to overcome these limitations, a team at the Wyss Institute for Biologically Inspired Engineering led by its Founding Director, Donald Ingber, M.D., Ph.D., had previously engineered a microfluidic «Organ - on - a-Chip» (Organ Chip) culture device in which cells from a human intestinal cell line originally isolated from a tumor were cultured in one of two parallel running channels, separated by a porous matrix - coated membrane from human blood vessel - derived endothelial cells in the adjacent channel.