The KININ meeting occurs every three years, assembling scientists and clinicians involved in the field
of bradykinin (kinins) and its related proteins (enzymes, cofactors, substrates, receptors, proteolytic systems, disease states, and developing therapies) for presentation of the latest ideas, research, drug development and therapeutics in these biologic systems.
This caused an excess
of bradykinin production, resulting in vessel leakage and swelling.
Then he turned his attention to a synthetic analogue
of bradykinin, called RMP - 7, that allowed 10 times more chemotherapy to be delivered to the tumor during the 20 - minute window that the blood - brain barrier was open.
During the early 1970s, a group of researchers in Brazil led by Sergio Henrique Ferreira discovered a family of peptides in the pit viper's venom that increased the activity
of bradykinin, a peptide that lowers blood pressure by causing blood vessels to dilate.
Not exact matches
This peptide family, which became known collectively as the
bradykinin potentiating factor (BPF), was also found to block the conversion
of angiotensin I to angiotensin II, a process that causes blood pressure to rise.
They found that a protein called GRK2 binds to and prevents delta opioid receptors on rat sensory neurons from responding normally to opioids, but when these peripheral neurons were exposed to a natural inflammatory molecule called
bradykinin, GRK2 moved away from the delta opioid receptors, setting off a biochemical reaction that restored the functioning
of these receptors.
Bradykinin enhances invasion
of malignant glioma into the brain parenchyma by inducing cells to undergo amoeboid migration.
Comparative effects
of immediate - release and extended - release aspirin on basal and
bradykinin - stimulated excretion
of thromboxane and prostacyclin metabolites.