«There is clear evidence
of brain alterations in impulsively aggressive individuals, which are not due to other factors,» Coccaro said.
In a matter of days, the mice developed many of the symptoms — and even
some of the brain alterations — seen in people with chronic pain.
Not exact matches
While it's possible that the accused is lazy, it's more probable that she's physically sick (depressed), and that relief is only a slight
alteration of her
brain chemistry away.
Too little food and / or nutrient deficiency can lead to depletion
of energy stores,
alteration of brain structure, and cardiac dysfunction.
Team physicians, athletic trainers, and other personnel responsible for the medical care
of athletes face no more challenging problem than the recognition, evaluation and management
of concussions (generally defined as injury to the
brain caused by a sudden acceleration or deceleration
of the head that results in any immediate, but temporary,
alteration in
brain functions, such as loss
of consciousness, blurred vision, dizziness, amnesia or loss
of memory).
She found that milestone achievement was abnormal in these monkeys: at six to eight weeks they were slow in starting to manipulate, and at ten months the increase in «motor disturbance behaviors» that normally occurs was prolonged.101 The author concludes, «These effects could occur as a result
of effects on vulnerable
brain processes during a sensitive period, interference with programming
of [normal]
brain development by endogenous [internal] agents or
alteration in early experiences.»
Physical punishment is associated with a range
of mental health problems in children, youth and adults, including depression, unhappiness, anxiety, feelings
of hopelessness, use
of drugs and alcohol, and general psychological maladjustment.26 — 29 These relationships may be mediated by disruptions in parent — child attachment resulting from pain inflicted by a caregiver, 30,31 by increased levels
of cortisol32 or by chemical disruption
of the
brain's mechanism for regulating stress.33 Researchers are also finding that physical punishment is linked to slower cognitive development and adversely affects academic achievement.34 These findings come from large longitudinal studies that control for a wide range
of potential confounders.35 Intriguing results are now emerging from neuroimaging studies, which suggest that physical punishment may reduce the volume
of the
brain's grey matter in areas associated with performance on the Wechsler Adult Intelligence Scale, third edition (WAIS - III).36 In addition, physical punishment can cause
alterations in the dopaminergic regions associated with vulnerability to the abuse
of drugs and alcohol.37
CERP 90 — 150 minutes When un-hampered by imposed fears
of spoiling or hindering maturation, the biochemical interplays
of frequent, close contact between parent and child create positive life - long
brain alterations in all who participate.
Advances in neuroscience and neurotechnology offer the potential for extremely precise observation, collection and even
alteration of human
brain activity.
Alterations in the
brain within the region
of the visual recognition network might be related to impaired selective attention and working memory in MDD, Dr. Zhao indicated.
Weight loss surgery can curb
alterations in
brain activity associated with obesity and improve cognitive function involved in planning, strategizing and organizing, according to a new study published in the Endocrine Society's Journal
of Clinical Endocrinology & Metabolism (JCEM).
The
alterations were found in patterns
of brain activity that reoccur, or «states» that the
brain moves in and out
of over time.
Previous studies
of PLEs have found
alterations in specific
brain networks, but the findings reveal that it is not just about damaged connections — the amount
of time spent in uncommon
brain states may contribute to psychosis..
«We found genetic
alterations in
brain metastases that could affect treatment decisions in more than half
of the patients in our study,» Dr Brastianos will say.
One line
of research traces memory loss in old age to epigenetic
alterations in
brain neurons.
Yet the stimulus is perfectly stable, and it is instead the pattern
of brain activity that is changing during viewing and producing the perceptual
alterations or the illusion
of an unstable object.
This epigenetic
alteration of gene activity in
brain cells that receive this neurotransmitter showed for the first time that dopamine deficiencies can affect a variety
of behavioral and physiological functions regulated in the prefrontal cortex.
Previous studies had linked increased LPA signaling to
alterations in architecture
of the fetal
brain and the initiation
of hydrocephalus (an accumulation
of brain fluid that distorts the
brain).
Late in life the human
brain suffers attrition
of certain neurons and undergoes chemical
alterations.
«Because our investigations on the post-stroke microvascular
alterations, including BSCB damage, have just begun, many questions remain,» said senior author Dr. Cesario Borlongan, professor and director
of the USF Center
of Excellence for Aging and
Brain Repair.
In addition,
brain imaging studies in rats and humans have shown
alterations in gray matter volume and white matter integrity in the
brain caused by the effects
of chronic pain.
Surprisingly, previous studies have found very similar
alterations in the
brains of adult chronic alcoholics.
Moderate to severe traumatic
brain injury was defined as a loss
of consciousness for more than 30 minutes,
alteration of consciousness
of more than 24 hours or amnesia for more than 24 hours.
After 10 days
of age, the manipulations reduced the distance flies could climb up tubes and the
alterations caused older flies to have signs
of neurodegeneration, including higher than normal levels
of brain cell death and degradation.
Additionally, the
brain structure abnormalities identified in this study reflect those found in children with depression or at high risk for developing the disorder, suggesting that these
alterations may be why children
of mothers with perinatal depression are more vulnerable to depression later in life.
«The
alteration of body weight is one
of the potential complications
of deep
brain stimulation as a treatment
of Parkinson's disease,» explains Marilena Aiello, SISSA researcher and first author
of the research.
In a report on one
of the two findings, published online Sept. 20 in Acta Neuropathologica, the investigators identified
alterations in a protein known as ATRX in human
brain tumors that arise as part
of a genetically inherited condition known as neurofibromatosis type 1 (NF1).
By revealing clear and consistent
alterations in key
brain regions, the findings shed light on the underlying mechanisms
of bipolar disorder.
«This study is important,» said Libero who is now a post-doctoral scholar at the University
of California - Davis MIND Institute (Medical Investigation
of Neurodevelopmental Disorders), «because we found that different combinations
of alterations in the
brain could lead to the same or different levels
of symptom severity.
«Most previous studies have focused on using one technique at a time, even though we have evidence that there are
alterations in the
brain in autism in terms
of structure, white - matter connectivity, and
brain chemical concentrations.
Despite the relationship between these
brain structure
alterations and fine particle exposure, the average residential levels
of fine particles in the study were well below the current acceptable limit set by the EU — only 0.5 percent
of the pregnant women in the study were exposed to levels considered unsafe.
According to the researchers, the findings provide experimental evidence that
alterations of our indigenous microbiota may have far - reaching consequences for the blood -
brain barrier function throughout life.
More recently,
brain scans have directly linked these conditions with changes in levels
of neurotransmitters — chemicals that convey messages across neurons — or
alterations in the number or structure
of neurons in different
brain areas.
TBI was confirmed if at least one clinical event was newly presented or worsened following the injury: loss
of consciousness or memory,
alteration of mental state, some neurological decline or
brain damage.
This is usually naturally corrected as they grow up, he says, but in some people, the sight
of an amputee at a very young age may have reinforce the
alterations in the
brain.
In a report on the mouse studies, published online Sept. 11 in PNAS (Proceedings
of the National Academy
of Sciences
of the United States
of America), the investigators say the genetic
alteration appears to release the biochemical «brakes» on
brain cells involved in body movement, reasoning and perception
of the world, triggering over-excited activity and reactions.
After a series
of genetic
alterations and exposure to a growth factor, male
brain cells became cancerous faster and more often than female
brain cells.
They also found that the disruption
of the connectivity
of these cells during
brain development causes
alterations in
brain oscillatory activity and disturbs the function
of place cells, a type
of pyramidal neuron that becomes active when an animal is located in a particular place in its environment.
Martins - Green and her team exposed mice to THS for up to six months, collecting
brain, liver, and serum samples after one, two, four, and six months
of exposure to test for hormonal
alterations, insulin resistance, metabolic syndrome, and damage to the liver and
brain.
The results showed a correlation between changes in his
brain and
alterations in the expression
of many families
of genes in his blood.
One current research focus is measuring differences in EEG smoking cue reactivity, as well as neurochemical and morphological
alterations in adult
brain architecture, related to age
of smoking onset during adolescence.
In the course
of this work, he has pioneered several new approaches in the fruit fly that have had important implications for mammalian neurobiology, including: the demonstration that the fruit fly has a sleep - like behavior similar to that
of mammals, studies
of physiological and behavioral consequences
of mutations in a neurotransmitter system affecting one
of the
brain's principal chemical signals, studies making highly localized genetic
alterations in the nervous system to alter behavior, and molecular identification
of genes causing naturally occurring variation in behavior.
It has been a longstanding hypothesis that
alterations in the microcircuit
of the prefrontal cortex and / or in its connectivity with the rest
of the
brain may be at the core
of many
of these disorders.
A longitudinal study
of college football players found
alterations in the white matter in their
brains after a single season.
To examine
alterations in
brain activation associated with pharmacologically induced memory impairment, we used functional MRI (fMRI) to study the effects
of lorazepam and scopolamine on a face - name
Brain gray matter
alterations and associated demographic profiles in adults with autism spectrum disorder: A meta - analysis
of voxel - based morphometry studies.
The lab has shown that when NMDAR function is impaired by a genetic mutation, they can recreate, in the mouse, the structural, neurochemical, and functional
alterations in the
brain that are characteristic
of schizophrenia — for example, cognitive and memory impairments for which there are currently no effective treatments.
Previous genetic studies in dogs, which can also develop OCD, have identified mutations that lead to
alterations in the function
of brain synapses — the points
of contact between cells conveying nerve signals.
Interestingly, estrogen effects within the
brain with consequent
alterations of leptin and insulin sensitivity could also be verified in male animals after estrogen administration (262).
For using light to manipulate the activities
of brain cells in living animals and for enabling rapid
alterations to the genomes
of living organisms.