Sentences with phrase «of brain alterations»

«There is clear evidence of brain alterations in impulsively aggressive individuals, which are not due to other factors,» Coccaro said.
In a matter of days, the mice developed many of the symptoms — and even some of the brain alterations — seen in people with chronic pain.

Not exact matches

While it's possible that the accused is lazy, it's more probable that she's physically sick (depressed), and that relief is only a slight alteration of her brain chemistry away.
Too little food and / or nutrient deficiency can lead to depletion of energy stores, alteration of brain structure, and cardiac dysfunction.
Team physicians, athletic trainers, and other personnel responsible for the medical care of athletes face no more challenging problem than the recognition, evaluation and management of concussions (generally defined as injury to the brain caused by a sudden acceleration or deceleration of the head that results in any immediate, but temporary, alteration in brain functions, such as loss of consciousness, blurred vision, dizziness, amnesia or loss of memory).
She found that milestone achievement was abnormal in these monkeys: at six to eight weeks they were slow in starting to manipulate, and at ten months the increase in «motor disturbance behaviors» that normally occurs was prolonged.101 The author concludes, «These effects could occur as a result of effects on vulnerable brain processes during a sensitive period, interference with programming of [normal] brain development by endogenous [internal] agents or alteration in early experiences.»
Physical punishment is associated with a range of mental health problems in children, youth and adults, including depression, unhappiness, anxiety, feelings of hopelessness, use of drugs and alcohol, and general psychological maladjustment.26 — 29 These relationships may be mediated by disruptions in parent — child attachment resulting from pain inflicted by a caregiver, 30,31 by increased levels of cortisol32 or by chemical disruption of the brain's mechanism for regulating stress.33 Researchers are also finding that physical punishment is linked to slower cognitive development and adversely affects academic achievement.34 These findings come from large longitudinal studies that control for a wide range of potential confounders.35 Intriguing results are now emerging from neuroimaging studies, which suggest that physical punishment may reduce the volume of the brain's grey matter in areas associated with performance on the Wechsler Adult Intelligence Scale, third edition (WAIS - III).36 In addition, physical punishment can cause alterations in the dopaminergic regions associated with vulnerability to the abuse of drugs and alcohol.37
CERP 90 — 150 minutes When un-hampered by imposed fears of spoiling or hindering maturation, the biochemical interplays of frequent, close contact between parent and child create positive life - long brain alterations in all who participate.
Advances in neuroscience and neurotechnology offer the potential for extremely precise observation, collection and even alteration of human brain activity.
Alterations in the brain within the region of the visual recognition network might be related to impaired selective attention and working memory in MDD, Dr. Zhao indicated.
Weight loss surgery can curb alterations in brain activity associated with obesity and improve cognitive function involved in planning, strategizing and organizing, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
The alterations were found in patterns of brain activity that reoccur, or «states» that the brain moves in and out of over time.
Previous studies of PLEs have found alterations in specific brain networks, but the findings reveal that it is not just about damaged connections — the amount of time spent in uncommon brain states may contribute to psychosis..
«We found genetic alterations in brain metastases that could affect treatment decisions in more than half of the patients in our study,» Dr Brastianos will say.
One line of research traces memory loss in old age to epigenetic alterations in brain neurons.
Yet the stimulus is perfectly stable, and it is instead the pattern of brain activity that is changing during viewing and producing the perceptual alterations or the illusion of an unstable object.
This epigenetic alteration of gene activity in brain cells that receive this neurotransmitter showed for the first time that dopamine deficiencies can affect a variety of behavioral and physiological functions regulated in the prefrontal cortex.
Previous studies had linked increased LPA signaling to alterations in architecture of the fetal brain and the initiation of hydrocephalus (an accumulation of brain fluid that distorts the brain).
Late in life the human brain suffers attrition of certain neurons and undergoes chemical alterations.
«Because our investigations on the post-stroke microvascular alterations, including BSCB damage, have just begun, many questions remain,» said senior author Dr. Cesario Borlongan, professor and director of the USF Center of Excellence for Aging and Brain Repair.
In addition, brain imaging studies in rats and humans have shown alterations in gray matter volume and white matter integrity in the brain caused by the effects of chronic pain.
Surprisingly, previous studies have found very similar alterations in the brains of adult chronic alcoholics.
Moderate to severe traumatic brain injury was defined as a loss of consciousness for more than 30 minutes, alteration of consciousness of more than 24 hours or amnesia for more than 24 hours.
After 10 days of age, the manipulations reduced the distance flies could climb up tubes and the alterations caused older flies to have signs of neurodegeneration, including higher than normal levels of brain cell death and degradation.
Additionally, the brain structure abnormalities identified in this study reflect those found in children with depression or at high risk for developing the disorder, suggesting that these alterations may be why children of mothers with perinatal depression are more vulnerable to depression later in life.
«The alteration of body weight is one of the potential complications of deep brain stimulation as a treatment of Parkinson's disease,» explains Marilena Aiello, SISSA researcher and first author of the research.
In a report on one of the two findings, published online Sept. 20 in Acta Neuropathologica, the investigators identified alterations in a protein known as ATRX in human brain tumors that arise as part of a genetically inherited condition known as neurofibromatosis type 1 (NF1).
By revealing clear and consistent alterations in key brain regions, the findings shed light on the underlying mechanisms of bipolar disorder.
«This study is important,» said Libero who is now a post-doctoral scholar at the University of California - Davis MIND Institute (Medical Investigation of Neurodevelopmental Disorders), «because we found that different combinations of alterations in the brain could lead to the same or different levels of symptom severity.
«Most previous studies have focused on using one technique at a time, even though we have evidence that there are alterations in the brain in autism in terms of structure, white - matter connectivity, and brain chemical concentrations.
Despite the relationship between these brain structure alterations and fine particle exposure, the average residential levels of fine particles in the study were well below the current acceptable limit set by the EU — only 0.5 percent of the pregnant women in the study were exposed to levels considered unsafe.
According to the researchers, the findings provide experimental evidence that alterations of our indigenous microbiota may have far - reaching consequences for the blood - brain barrier function throughout life.
More recently, brain scans have directly linked these conditions with changes in levels of neurotransmitters — chemicals that convey messages across neurons — or alterations in the number or structure of neurons in different brain areas.
TBI was confirmed if at least one clinical event was newly presented or worsened following the injury: loss of consciousness or memory, alteration of mental state, some neurological decline or brain damage.
This is usually naturally corrected as they grow up, he says, but in some people, the sight of an amputee at a very young age may have reinforce the alterations in the brain.
In a report on the mouse studies, published online Sept. 11 in PNAS (Proceedings of the National Academy of Sciences of the United States of America), the investigators say the genetic alteration appears to release the biochemical «brakes» on brain cells involved in body movement, reasoning and perception of the world, triggering over-excited activity and reactions.
After a series of genetic alterations and exposure to a growth factor, male brain cells became cancerous faster and more often than female brain cells.
They also found that the disruption of the connectivity of these cells during brain development causes alterations in brain oscillatory activity and disturbs the function of place cells, a type of pyramidal neuron that becomes active when an animal is located in a particular place in its environment.
Martins - Green and her team exposed mice to THS for up to six months, collecting brain, liver, and serum samples after one, two, four, and six months of exposure to test for hormonal alterations, insulin resistance, metabolic syndrome, and damage to the liver and brain.
The results showed a correlation between changes in his brain and alterations in the expression of many families of genes in his blood.
One current research focus is measuring differences in EEG smoking cue reactivity, as well as neurochemical and morphological alterations in adult brain architecture, related to age of smoking onset during adolescence.
In the course of this work, he has pioneered several new approaches in the fruit fly that have had important implications for mammalian neurobiology, including: the demonstration that the fruit fly has a sleep - like behavior similar to that of mammals, studies of physiological and behavioral consequences of mutations in a neurotransmitter system affecting one of the brain's principal chemical signals, studies making highly localized genetic alterations in the nervous system to alter behavior, and molecular identification of genes causing naturally occurring variation in behavior.
It has been a longstanding hypothesis that alterations in the microcircuit of the prefrontal cortex and / or in its connectivity with the rest of the brain may be at the core of many of these disorders.
A longitudinal study of college football players found alterations in the white matter in their brains after a single season.
To examine alterations in brain activation associated with pharmacologically induced memory impairment, we used functional MRI (fMRI) to study the effects of lorazepam and scopolamine on a face - name
Brain gray matter alterations and associated demographic profiles in adults with autism spectrum disorder: A meta - analysis of voxel - based morphometry studies.
The lab has shown that when NMDAR function is impaired by a genetic mutation, they can recreate, in the mouse, the structural, neurochemical, and functional alterations in the brain that are characteristic of schizophrenia — for example, cognitive and memory impairments for which there are currently no effective treatments.
Previous genetic studies in dogs, which can also develop OCD, have identified mutations that lead to alterations in the function of brain synapses — the points of contact between cells conveying nerve signals.
Interestingly, estrogen effects within the brain with consequent alterations of leptin and insulin sensitivity could also be verified in male animals after estrogen administration (262).
For using light to manipulate the activities of brain cells in living animals and for enabling rapid alterations to the genomes of living organisms.
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