Research shows that excessive experience with toxic stress can disrupt the
development of brain circuits related to stress response — and to learning and memory.
This mechanism allows them to position themselves correctly in the different layers of the cortex, a key step in the
development of brain circuits.
In order to better understand serotonin's influence in the developing brain, Alexandre Dayer's team in the Psychiatry and Fundamental Neuroscience Departments of UNIGE's Faculty of medicine examined a particular receptor for this neurotransmitter, and its role in the
formation of brain circuits.
The Obama administration's neuroscience initiative highlights new technologies to better understand the workings
of brain circuits on both a small and large scale.
«New
study of brain circuits finds key links to symptoms of depression: Altering distinct brain pathways found to aid symptoms such as social withdrawal and helplessness behavior.»
Whatever is the goal, I work on that and I think about what
types of brain circuits are going to be involved and how to most effectively engage them.
Christianson said the findings set the stage for a large - scale
investigation of the brain circuits that work together to orchestrate responses to social emotional information with the hope that such research will lead to better treatment for people with conditions marked by aberrant social cognition, such as autism or schizophrenia.
«Our goal was to characterize the development
of brain circuits involved in appetite regulation, using a mouse model for Prader - Willi syndrome.
«When other
portions of the brain circuit related to speech were also affected according to our blood flow measurements, we saw more severe stuttering in both children and adults,» said first author Jay Desai, MD, a clinical neurologist at CHLA.
Neuroscientists at Duke University have introduced a new paradigm for brain - machine interfaces that investigates the physiological properties and
adaptability of brain circuits, and how the brains of two or more animals can work together to complete simple tasks.
«In essence, this points to a relative
immaturity of brain circuits in FXS,» added Tiago Gonçalves, a former post-doc in Portera - Cailliau's lab and first author of the study.
«The cortical folding pattern itself may not be so important, but the disturbances in connections between brain regions implicated by the changes in cortical folding could provide critical clues to deficits in the
integrity of brain circuits that contribute to symptoms and functional impairment in schizophrenia,» commented Dr. John Krystal, Editor of Biological Psychiatry.
«We wanted to find the link between the abnormal structure of synapses in the FXS mouse, and the behavioral abnormalities at the
level of brain circuits; that had not been previously established,» said senior author Dr. Carlos Portera - Cailliau, an associate professor in the departments of neurology and neurobiology.
In the study, HaDi MaBouDi of Queen Mary University of London and colleagues built a realistic computational
model of the brain circuits used by bees to process olfactory information.
An MRI
Fingerprint of Brain Circuit Breakdown in Alzheimer's Terrance Kummer, MD, PhD Washington University School of Medicine (Saint Louis, MO)
«We hope this atlas will be a roadmap for the field to explore the relationship between specific cell types, signaling pathways, receptors, and the physiological
function of brain circuits,» Kriegstein added.
Chronic stress associated with lack of safe and secure attachment can impair the
formation of brain circuits and alter levels of stress hormones, resulting in emotional and biological dysregulation, anxiety, and depression.
«To understand and address the causes of speech disorders requires a fundamental
understanding of the brain circuits and computations involved in learning and controlling speech,» said Dr. Roberts, a Thomas O. Hicks Scholar in Medical Research.
We're funding researchers to investigate how drugs alter what genes are activated such that they modify the function of the cells, and how this, in turn, modifies the functions
of brain circuits, and how that modifies behavior.
«Absence of serotonin alters development, function
of brain circuits: Researchers create first complete model of serotonin's role.»
Some of these brain circuits also appeared to be sensitive to the fly's internal clock, as post-meal sleepiness happened less around dusk than at other times of day.