Sentences with phrase «of brain development disorders»

Exposures of pregnant women and children to common thyroid - hormone - disrupting toxins may be linked to the increased incidence of brain development disorders, according to a review published in Endocrine Connections.

Not exact matches

But it's becoming increasingly clear that the effects are serious, and range from momentary unconsciousness, confusion and memory loss — such as that suffered by Kramer — through to whiplash, debilitating headaches, and in the longer term the development of any number of emotional distresses and disorders linked to brain trauma.

Early organization of the nonlinear right brain and development of a predisposition to psychiatric disorders.

Dr. Perry's research includes: the effects of prenatal drug exposure on brain development, the neurobiology of human neuropsychiatric disorders, the neurophysiology of traumatic life events, and long - term cognitive, behavioral, emotional, social and physiological effects of neglect and trauma in children, adolescents and adults.

Recently, researchers from Harvard and Mt Sinai found that both environmental chemicals and environmental stress can disrupt the development of a fetus» brain and negatively impact the baby's long - term health, even increasing the risk of autism spectrum disorders.

Dr. Giedd's research team seeks to use cutting edge technologies to explore the relationship between genes, brain and behavior in healthy development and in neuropsychiatric disorders of childhood onset.

Professor Jianfeng Feng commented that new technology has made it possible to conduct this trail - blazing study: «human intelligence is a widely and hotly debated topic and only recently have advanced brain imaging techniques, such as those used in our current study, given us the opportunity to gain sufficient insights to resolve this and inform developments in artificial intelligence, as well as help establish the basis for understanding and diagnosis of debilitating human mental disorders such as schizophrenia and depression.»

If clinicians could use brain scans to identify vulnerable high - risk individuals in early adolescence when the brain is still developing, it may be possible to curb the development of the disorder and help prevent its most debilitating effects.

For example, knowing the precise brain activity involved could shed light on disorders in which body awareness is disrupted, such as schizophrenia, and help with the development of prosthetic limbs that are more easily incorporated into body image.

If the zinc ions or the transcription factor MTF1 were specifically inhibited in the brain, it is possible that the development of a seizure disorder could be prevented.

«The project's goal is to accelerate the development of technologies for mapping the brain's circuitry in animal models, specifically in the marmoset monkey, whose neural circuits are much closer to human compared with rodent models, and to connect the results to the diagnosis and treatment of human neurological disorders and mental illness.»

They have also used state - of - the - art information about brain development to accurately pinpoint new genes and biological pathways implicated in this disorder.

There may be brain changes after trauma that act as a risk marker for development of later illnesses, including bipolar disorder.

For example, brain anatomy could be more closely monitored in those people where there is suspicion of an increased risk of developing a mental disorder (the children of parents with mental health problems, for example), so that the probability of developing a pathology that interferes with their normal development can be estimated.

Scientists working in the Smurfit Institute of Genetics at Trinity College Dublin and the Department of Psychiatry, RCSI, have discovered that abnormalities in the integrity of the BBB may be a critical component in the development of schizophrenia and other brain disorders.

These early developments produce brain networks with a balance of influences that will excite and inhibit the brain and a disruption to this natural order has been associated with a number of common neurodevelopmental disorders including TS.

«There have been a series of discoveries over the last five years showing that proteins that control RNA degradation are very important for brain development and, when they are mutated, you can have spasticity or other movement disorders,» Dr. Colak says.

These disorders are associated with abnormal development of the brain.

It is known that during this teenaged phase of brain development, adolescents are particularly vulnerable to psychiatric disorders, including schizophrenia, depression and drug addiction.

Like misdirected letters and packages at the post office, the neurons made from bipolar disorder patients also differed in how they were «addressed» during development for delivery to certain areas of the brain.

German and Canadian scientists have built a three dimensional map of the human brain to help in the development of new treatments for neurological disorders like Alzheimer's and Parkinson's disease.

So, the new findings support the idea that genetic differences expressed early during brain development may have a lot to do with the development of bipolar disorder symptoms — and other mental health conditions that arise later in life, especially in the teen and young adult years.

It is a big idea that could help unravel mysteries of brain development and evolution, and help link neurological and psychiatric disorders to abnormalities in brain structure.

The critical role these changes play in brain development highlights the importance and urgency in understanding neural circuits in more detail and suggests new avenues for investigating the underlying causes of developmental disorders such as autism.

The new finding is the latest evidence supporting a growing precision medicine model of psychiatric disease in which disruptions of certain genes during brain development contribute to a person's risk for multiple psychiatric disorders, with other genetic or epigenetic drivers, random developmental events, or environmental influences determining the specific disease an individual develops, said senior author Benjamin Cheyette, MD, PhD, an associate professor of psychiatry and a member of the UCSF Weill Institute for Neurosciences and the Kavli Institute for Fundamental Neuroscience at UCSF.

Preclinical studies suggest that Cdk5 is a gene that is important for the normal wiring of the brain during early development and may be involved in some neurodegenerative disorders, including ALS, Parkinson's and Alzheimer's disease.

Neurocutaneous disorders are caused by abnormal development of cells in the embryonic stage, leading to tumors in various parts of the body, including the skin, organs, bones, brain and spinal cord.

Many of the eight genes are active during brain development and may play a role in neuropsychiatric disorders such as autism and schizophrenia, Sanders says.

Recent research discoveries in the development of brain disorders could pave the way to new therapies for treating seizures, and even some children with autism, says a leading oncologist and researcher at the University of Alberta.

«Some neuropsychiatric disorders, such as schizophrenia and autism, are characterized by the abnormal development of synaptic connectivity in certain key parts of the brain,» explains Schneggenburger.

«This study offers new insights about the brain in AN, which we are using to guide treatment development efforts, and reduce stigma associated with this life - threatening disorder,» added Kaye, who is a Professor of Psychiatry and Director of the Eating Disorder Program disorder,» added Kaye, who is a Professor of Psychiatry and Director of the Eating Disorder Program Disorder Program at UCSD.

But researchers are beginning to uncover a biological explanation for the problem: they have found a gene that may contribute to its development as well as a pathological signature of the disorder in the brain.

New research into the causes of this baffling disorder is focusing on genes that control the development of the brain

Though these findings have been obtained in mice, the scientists hypothesize that disrupted coordination between the development of the microglia and that of the brain contributes to an increased risk of such neurodevelopmental disorders as autism and schizophrenia in human beings.

The involvement of this enzyme in susceptibility to oxidative stress, which has frequently been observed in autistic children, its association with gastrointestinal diseases — which often accompany autistic disorders — and its role in nerve development and neurotransmission mean it is an ideal candidate for deregulation of its expression to lead to the abnormal brain development observed in ASD.

And if we better understand the development of our brain, new treatment options for disorders of the brain can presumably arise from this over the long term.»

Scientists studying brain diseases may need to look beyond nerve cells and start paying attention to the star - shaped cells known as «astrocytes,» because they play specialized roles in the development and maintenance of nerve circuits and may contribute to a wide range of disorders, according to a new study by UC San Francisco researchers.

ASD is a complex disorder of brain development.

A new study led by scientists at The Scripps Research Institute (TSRI) is giving researchers a first look at the early stages of brain development in patients with Fragile X syndrome, a disorder that causes mild to severe intellectual disability and is the most common genetic cause of autism spectrum disorder.

According to the National Alliance on Mental Illness: «It is too early to classify schizophrenia as either a neurodevelopmental (impairment of the growth and development of the brain) or a neurodegenerative (progressive loss of structure or function of neurons) disorder, as both seem to occur over the course of the illness.

In the new study, the researchers discovered that during the second trimester of human brain development, oRG cells express genes related to a fundamental signaling pathway called mTOR, defects in which have previously been implicated in autism and several other psychiatric disorders.

«The method thus opens up completely new opportunities for investigating disorders in the architecture of the developing human brain,» explains Dr. Julia Ladewig, who leads a working group on brain development.

The cause of his disorder has yet to be pinpointed, but it almost certainly stems from a problem in the early development of his brain.

Animal models and clinical trials have shown that antioxidants and anti-inflammatory drugs could not only reduce symptoms associated with the disorders but also prevent the appearance of neurobiological abnormalities and transition to psychosis if given early during brain development.

Similarly, Neanderthal variants impacting development of a particular suspect brain area may help to inform cognitive disability seen in certain brain disorders, say the researchers.

They're now reporting in ACS» Journal of Agricultural and Food Chemistry that a compound from hops could protect brain cells from damage — and potentially slow the development of disorders such as Alzheimer's and Parkinson's diseases.

These so - called bioreactors, and the mini-brains they foster, should open other new and valuable windows into human brain development, brain disorders and drug testing — and perhaps even produce neurons for treatment of Parkinson's disease and other disorders, the investigators say.

Schizophrenia is generally considered to be a disorder of brain development and it shares many risk factors, both genetic and environmental, with other neurodevelopmental disorders such as autism and intellectual disability.

Pattwell studies the development of the brain, particularly the neural circuits associated with fear, anxiety, and post-traumatic stress disorder using mice as a model.

Increased expression of a gene linked to autism spectrum disorders (ASDs) leads to a remodeling of dendrites during brain development, according to a new study conducted in cultured neurons and an ASD mouse model published in JNeurosci.