The evolution
of brain genes, therefore, appears purely human, the scientists say.
The brain attempts to adapt and respond to those challenges and that occurs in large part through changes in expression
of brain genes through epigenetic mechanisms.
Not exact matches
Since I surround myself with adventurous people and feed my
brain with a lot
of curious indulgences, it only makes sense that I like to travel often, even though I don't possess the sexy - sounding «wanderlust
gene.»
The Kamens claim the main thing that distinguishes their foundation from other
brain tumor foundations is their focus on pediatric
brain cancer specifically, as well as their close ties with pharmaceutical and biotech companies working in the fields
of immunotherapy and target
gene therapy.
And you only appear cute to your mother because
of biological chemistry: her
brain tricks her into finding you attractive in order to carry on her
genes.
Erzen writes that «studies such as those
of Simon LeVay and Dean Hamer, which argue that a gay
brain or gay
genes exist, are revered as the basis for a minority identity and entrance into U.S. civil rights discourse.»
On the contrary, he finds it useful to ponder an array
of reductionist attempts to explain the existence
of religion, from that which seeks to pinpoint the area
of the human
brain or the specific
genes connected to religiosity to that which sees religion as a malfunction
of the human mind or a vestigial remnant from a primitive stage
of human development suitable only for whimpering, immature dullards (a point
of view championed by the new atheists).
It is for this reason that utopian thinking led some
of its modern promoters, such as Arthur Koestler and Carl Sagan, to propose ways
of «improving» human beings by biological manipulation such as surgical removal
of certain centers in the
brain or by genetic engineering to remove «bad»
genes.
2) As to Neanderthal they did not have the
brain capacity (Steve Olson, Mapping Human History:
Genes, Race, and Our Common Origins (New York: Houghton Mifflin Co., 2002), to wonder, thus not the first Adam 3) Nicodemus went to Jesus in the dark
of night and Jesus said «I have spoken to you
of earthly things and you do not believe so how can you believe when I speak
of heavenly things».
Blakemore argues that a single
gene mutation could in fact have been the cause
of this increase - for in fact only one extra cell - division step would cause a doubling
of brain size.
We can compare the diverse tasks performed by a colony to the many proteins generated by
gene transcription, to various cell types
of a developing embryo, or to the firing patterns
of neurons in the
brain.
What all these have in common is that, without any central control, individual units (
genes, cells neurons or workers) respond to simple, local information, in ways that allow the whole system (cells,
brains, organisms or colonies) to function: the appropriate number
of units performs each activity at the appropriate time.
The football
brain Theo
gene is wengers influence an lack
of development.
Neuroscientists have over the past decade uncovered evidence, both in rodent and human studies, that parental caregiving, especially in moments
of stress, affects children's development not only on the level
of hormones and
brain chemicals, but even more deeply, on the level
of gene expression.
Genetic factors drive this early overproduction
of neurons, Schore explains, but the
brain awaits direction from the social environment, or epigenetic processes, to determine which synapses or connections are to be pruned, which should be maintained, and which
genes are turned on or off.
Early life stress, such as an extreme lack
of parental affection, has lasting effects on a
gene important to normal
brain processes and is also tied to mental disorders.
And while scientists can't point to a «happiness»
gene or isolate a «moody» nodule in the
brain, an abundance
of research shows that your baby's temperament — her basic emotional and social style — is hardwired in her
brain.
Procured from algae, algal oil is source
of DHA, an important long - chain omega - 3 that supports
brain development, immune balance, and healthy
gene expression.
Other research shows that ADHD children with a particular
gene variation have thinner tissue in the area
of the
brain that's associated with attention.
Observed parenting behaviors interact with a polymorphism
of the
brain - derived neurotrophic factor
gene to predict the emergence
of oppositional defiant and callous — unemotional behaviors at age 3 years
The disruption
of prenatal cellular activity in zebra fish, which share 80 percent
of their
genes with humans and are considered a good model for studying human
brain development, seemed to result in hyperactivity, according to the Canadian study, which was published Monday in the Proceedings
of the National Academy
of Sciences.
Although this could mean that new
genes are turned on in middle childhood, it is more likely that the same
genes have different effects in the
brains of 8 - year - olds as compared to 4 - year - olds (Plomin, 1986).
(Some research has homed in on a
gene that codes for a transporter
of the
brain chemical serotonin.)
He looked closer at a specific
gene known to regulate levels
of the
brain neurotransmitter serotonin — a lack
of which is found in people with depression.
«We wondered whether some
of those same
genes could also cause seizures if they were expressed in the
brain and, if so, whether those
genes would also place people with epilepsy at risk not only for having epilepsy but also an abnormal heart beat and risk
of death,» said Noebels.
«Some people are protected from the effects
of sleep deprivation by this particular
gene variation but, for most
of us, sleep loss does something to the
brain that simply prevents us from switching gears when circumstances change.»
But over the past decade, researchers have identified hundreds
of gene variations that seem to affect
brain development in ways that increase the risk
of autism.
The researchers then found that these same
genes carry an additional risk for a phenomenon called spreading depolarization, a slowly - progressing, temporary electrical blackout
of a region in the
brain.
She demonstrated that early experience leads to lasting changes in the molecular structure
of the
brain and discovered a
gene involved in the spread
of brain cancer cells into healthy
brain tissue.
There has been considerable interest, for example, in a
gene that produces low levels
of an enzyme called monoamine oxidase A (MAOA) in the
brain.
What's more, these
genes are expressed in both the auditory and visual cortices
of the
brain during childhood development, the researchers report today in the Proceedings
of the National Academy
of Sciences.
Another
of the
genes, SLC4A4, is involved in regulating the pH
of the
brain, which has been linked to anxiety and panic attacks.
These included sites involved in regulating
gene activity during
brain development and initiating the transcription
of genes.
They have discovered two new
genes implicated in two medical conditions and conducted one
of the cheapest clinical trials in history, formulating a nutritional formula from pig
brains that supplements a protein missing in a rare developmental disorder.
Dr. Giedd's research team seeks to use cutting edge technologies to explore the relationship between
genes,
brain and behavior in healthy development and in neuropsychiatric disorders
of childhood onset.
«Manyfold more
genes were regulated in the resilient animals than in the susceptible animals across several
brain regions,» says Eric Nestler, director of The Friedman Brain Institute at Icahn School of Medicine at Mount S
brain regions,» says Eric Nestler, director
of The Friedman
Brain Institute at Icahn School of Medicine at Mount S
Brain Institute at Icahn School
of Medicine at Mount Sinai.
Gene therapy delivered to a specific part
of the
brain reverses symptoms
of depression in a mouse model
of the disease — potentially laying the groundwork for a new approach to treating severe cases
of human depression in which drugs are ineffective.
A new mouse model
of a genetically - linked type
of autism reveals more about the role
of genes in the disorder and the underlying
brain changes associated with autism's social and learning problems.
15 years after a
gene defect was found to increase the risk
of schizophrenia 30-fold, scientists have figured out how it might cause the
brain disorder's debilitating symptoms
A number
of individual
genes have been linked to suicide, such as those involved in the
brain's response to mood - lifting serotonin, and a signalling molecule called
brain - derived neurotrophic factor (BDNF), which regulates the
brain's response to stress.
Their
brains differed in the activity
of over a hundred
genes that provide cells with energy, influence chemical communications in the
brain and strengthen the connection between nerve cells.
Because this imprinting affects hundreds
of genes that are non-coding, including microRNAs and non-coding RNAs, it's a very interesting fine - tuning mechanism for the dosage
of gene expression in the
brain and elsewhere in the body.»
Research published in the October 21 issue
of Science Translational Medicine uses a virus to deliver an extra dose
of the
gene p11 to the adult mouse
brain.
While they don't have definite answers, besides having good
genes, Kawas said, the answer is probably a combination
of being resilient to Alzheimer's Disease and also that they did not develop other dementia - causing conditions, such as microscopic infarctions that occur when blood flow is blocked from certain regions
of the
brain and hippocampal sclerosis, which causes neuron loss.
Apparently, NPAS4 accounts for some addiction - related learning and memory processes in the
brain, but not all
of them, meaning that HDAC5 must be regulating additional
genes that reduce relapse events.
But, he adds, «thinking about delivering a
gene to the
brain poses all sorts
of challenges.»
Most
of these
genes are predominantly expressed in
brain tissue.
Crucially, this molecule seems to damp down the activity
of a
gene involved in glutamate signalling in the
brain.
Examples
of gene networks in the hippocampus affected by
brain trauma.
Nearly two dozen
of the altered
genes are present in both the hippocampus and the blood, which presents the possibility that scientists could develop a
gene - based blood test to determine whether a
brain injury has occurred, and that measuring some
of those
genes could help doctors predict whether a person is likely to develop Alzheimer's or other disorders.