They found that
levels of the brain protein were increased throughout the course of HD — even in carriers of the HD genetic mutation who were many years from showing symptoms of the disease.
A new study conducted at the University of Haifa and published recently in the Journal of Neuroscience has identified
activity of brain proteins associated with memory impairments in Alzheimer's disease, and has also found that «repairing» this activity leads to an improvement in memory.
Newswise — A new study conducted at the University of Haifa and published recently in the Journal of Neuroscience has identified activity
of brain proteins associated with memory impairments in Alzheimer's disease, and has also found that «repairing» this activity leads to an improvement in memory.
Still other
properties of this brain protein may be waiting to be discovered, since BAI1 is an «orphan» G - protein coupled receptor or GPCR, for which no ligand has been identified (yet).
Brains that have been voxelated into ~ 700 cubes will be prepared using automated microscale sample processing and analyzed using high - throughput reversed - phase liquid chromatography coupled online with high - resolution mass spectrometry to obtain both the spatial localization and relative
abundance of brain proteins.
If elevated levels
of the brain protein do lead to non-coping humans as it did for mice, the scientists suggest that by interfering with this protein they could also help fight stress and depression disorders.