Not exact matches
The US Food and Drug Administration (FDA) partnered with Flatiron in 2016 because it is hopeful that one day this channel
of real - world data can lead to
breakthroughs in
treatment that clinical trials may not accomplish alone.
These products — largely innovative and pricey specialty medications that include
breakthrough Hepatitis C
treatments and immuno - oncology drugs — reflect the increased productivity and improved pipelines
of pharma's R&D departments in recent years.
«If we determine that our [
treatment] can prevent or delay the onset
of symptoms in healthy yet high - risk populations, this would represent a tremendous
breakthrough for those that may face this debilitating disease.»
But for all
of the attention paid to its cancer drug pipeline, Bristol just scored a
breakthrough therapy designation from the Food and Drug Administration for a
treatment that targets hepatitis C.
«Today's approval marks another first in the field
of gene therapy — both in how the therapy works and in expanding the use
of gene therapy beyond the
treatment of cancer to the
treatment of vision loss — and this milestone reinforces the potential
of this
breakthrough approach in treating a wide - range
of challenging diseases,» FDA Commissioner Scott Gottlieb said in a statement.
Effective PARP inhibitors are particularly sought after by drugmakers because
of their potential to be used in combination with other types
of cancer
treatments to create new
breakthroughs in
treatments.
No. 2: Alzheimer's disease
treatment nets a
breakthrough Roughly 99 %
of all Alzheimer's drugs to enter human trials have ended up in the trash heap, but trials are under way evaluating drugs that could soon reshape patient
treatment.
David and Goliath is so compelling because the points are made through the incredible true stories
of real - life underdogs and «giants»: the man whose emotionally stunted single - mindedness enabled
breakthroughs in leukaemia
treatment; the French painters who chose to go outside the established art system that rejected them, and ended up launching the Impressionist movement.
Founder & CEO
of U.S. Water, Allan Bly, commented on the launch
of new PhosZero ™, stating, «I am very proud
of our scientists for developing this great
breakthrough in sustainable
treatment for cooling water.
The hyperbaric oxygen therapy he received could be a major
breakthrough in the
treatment of athletes (or anyone) suffering from concussions or concussion - related issues, and Bryan continuing to receive therapy while successfully keeping his career as a wrestler going would only add to that
breakthrough.
An internationally recognized expert on the
treatment of self - injury, she lectures extensively on the subject and is co-author
of the book, Bodily Harm: The
Breakthrough Healing Program for Self - Injurers as well as Self Injury: A Manual for School Professionals.
They claim they have the breadth
of clinical experience and years
of research, which have translated into scientific
breakthroughs in the
treatment of infertility, and ultimately offering the latest medical advances for patients along with the highest fertility success rates.
A major
breakthrough in the
treatment of cancer was the development
of multiple chemotherapeutic agents (known as combination chemotherapy).
Located next to the Buffalo General Medical Center, the facility brings Kaleida Health physicians and SUNY Buffalo researchers together to join in the advancements in care and
treatment, development
of new medical technologies, discovery
of breakthroughs and the spin off new biotechnology businesses and jobs.
That's why Science recognized the idea
of «
treatment as prevention» as its scientific
breakthrough of the year, crediting the lab
of infectious diseases researcher Myron Cohen, a physician - scientist at the University
of North Carolina School (UNC)
of Medicine in Chapel Hill, with discovering and investigating one
of the most promising antiretroviral drugs, HPTN 052.
AveXis, Inc., a clinical - stage gene therapy company developing
treatments for patients suffering from rare and life - threatening neurological genetic diseases, announced in July 2016 that the U.S. Food and Drug Administration (FDA) granted
Breakthrough Therapy Designation for the
treatment based on preliminary clinical results from the trial
of AVXS - 101.
«It is truly a
breakthrough for advancing detection and
treatment of brain injuries.»
This link could be a
breakthrough in developing new
treatments that better target the causes
of the disorder.
Dr Lee Campbell, Research Projects and Science Communications Manager at Cancer Research Wales, who part - fund the study, commented: «This is an exciting
breakthrough as cancer stem cells are thought to be responsible for the failure
of many cancer
treatments and the re-emergence
of cancers, often many years after the initial disease.
The
breakthrough has resulted from the merger
of interlocking fields — gene therapy and cell therapy — which are now spawning near - miraculous
treatments and cures.
In 2011, the HPTN 052 study investigators reported a
breakthrough: Starting HIV
treatment early, when the immune system is relatively healthy, reduced the risk
of sexually transmitting the virus to an uninfected partner by 96 percent over 18 months.
Of the 66 patients (3.4 %) who failed to achieve SVR12, 38 patients (1.9 %) experienced virological failure: 36 due to relapse and two patients due to on -
treatment breakthrough (with documented non-compliance).
«Hepatitis C: Life - threatening barriers in access to
breakthrough drugs in US: First systematic study
of Medicaid policies for hepatitis C
treatment.»
We hope this leads to the ability to design, study and test new therapies for every patient on their own cells in the lab, leading to new
treatments and
breakthroughs in personalized medicine for individuals with a variety
of lung diseases, including cystic fibrosis,» explained lead author Katherine McCauley, a PhD student at BUSM.
However, she argues that the results are a
breakthrough in cancer research as it may be the first step towards effective
treatment of cancer stem cells, i.e. the cells believed to cause metastases.
Dr. Alan S. Cross, Professor
of Medicine at University
of Maryland School
of Medicine, who was not involved in the research, shared his input: «This is a major conceptual
breakthrough in our understanding
of infection and immune disease mechanisms and may have implications for novel approaches to the
treatment of other diseases characterized by cytokine storm.
In its first clinical trial, a
breakthrough antibody therapy produced at least partial remissions in a third
of patients with multiple myeloma who had exhausted multiple prior
treatments, investigators at Dana - Farber Cancer Institute and other organizations report today online in the New England Journal
of Medicine.
Helen Grant described how a team at Strathclyde University has developed an artificial liver, which could be a significant
breakthrough in the
treatment of liver failure.
«This is a revolutionary
breakthrough in the
treatment of this disease and represents a huge improvement in the quality
of life
of those affected,» says the Vienna hepatologist.
«If we can, maybe there's a chance to make great
breakthroughs in terms
of treatment.»
Cancer immunotherapy has therefore become one
of the
breakthroughs in tumor
treatment.
In July neurobiologist Hans Keirstead
of the University
of California at Irvine announced that the
breakthrough experiment by his research team could lead to
treatment of traumatic spinal injuries in humans.
«Today's approval marks another first in the field
of gene therapy — both in how the therapy works and in expanding the use
of gene therapy beyond the
treatment of cancer to the
treatment of vision loss — and this milestone reinforces the potential
of this
breakthrough approach in treating a wide - range
of challenging diseases,» FDA Commissioner Scott Gottlieb said in a statement.
This could well be a
breakthrough in the
treatment of this disorder.
Finding ways to use CaSR - directed drugs also for the
treatment of diseases such as diabetes, Alzheimer's disease and various types
of cancer, would be a
breakthrough.
A new book tells the tale
of Gleevec, a
breakthrough treatment that targets cancer at the genetic level
The
breakthrough treatment comes, however, at a price that may place it out
of reach for all but the wealthiest or best - insured patients.
In July 2014, the U.S. Food and Drug Administration granted CTL019 its
Breakthrough Therapy designation for the
treatment of relapsed and refractory adult and pediatric ALL, a step which is intended to expedite the development and review
of new medicines that treat serious or life - threatening conditions, if a therapy has demonstrated substantial advantages over available
treatments.
In a major
breakthrough for ovarian and uterine cancers, Yale researchers have defined the genetic landscape
of rare, highly aggressive tumors called carcinosarcomas (CSs), pointing the way to possible new
treatments.
Some EMDR proponents have called it a «miracle cure» and «paradigm shift,» and ABC's 20/20 proclaimed it an «exciting
breakthrough» in the
treatment of anxiety.
The study can be regarded as a
breakthrough, as the results change our understanding
of the pathogenesis
of AMD and also open new avenues for the
treatment of the dry form
of AMD.
Taking that concept into biomedical research has yielded a
breakthrough: This past May the mTOR inhibitor everolimus was approved by the U.S. Food and Drug Administration for the
treatment of advanced pNET, the first drug in this class approved for this disease.
Thanks to a
breakthrough led by researchers in the Cockrell School
of Engineering at The University
of Texas at Austin,
treatment for hemophilia can now be administered via a biodegradable system, a capsule, giving people affected by the hereditary bleeding disorder hope for a less expensive, less painful
treatment option than conventional injections or infusions.
Introduced in 1992, ICSI was widely regarded as a
breakthrough in the
treatment of male infertility, which is the problem for an estimated 40 per cent
of infertile couples.
[This was the
breakthrough in 1996 that led to the first powerful anti-HIV
treatments ACTG 320 was one
of the first studies that showed this.]
Charles Akle, Chairman
of Immodulon, said: «The results from this study are remarkable and represent a significant
breakthrough in the development
of immunotherapy for the
treatment of pancreatic cancer.
The research questions current medical thinking about serious ACL injuries and could signal a
breakthrough in the
treatment of patients with serious ACL injuries.
This new result could lead to a
breakthrough in the way nanoparticles are used in the
treatment and diagnosis
of brain diseases,» explained the co-investigator, Hélène Girouard.
Use
of thrombin generation assay to personalize
treatment of breakthrough bleeds in a patient with hemophilia and inhibitors receiving prophylaxis with emicizumab
If it can be repeated in humans it would be a
breakthrough in the
treatment of patients with heart disease and could save thousands
of lives.