Sentences with phrase «of calcium release»

This might be because adaptor molecules like RhoH and SLP76 can affect the signaling events downstream of calcium release from the ER, or might indicate the existence for a possible positive feedback pathway from calcium signaling to the upstream of adaptor molecules.

The role of calcium release activated calcium channels in osteoclast differentiation.

Moreover, because calcium pumping requires energy, the low levels of calcium release also lower the metabolic demands of making a continuous, hour - long mating call.

«The small amount of calcium released per stimulus is the key element that permits the calcium pumps in midshipman swimbladder muscle to keep up over long periods of high - frequency stimulation,» Rome explains.

Rome and colleagues therefore measured the amount of calcium released and pumped by midshipman swimbladder muscles as they repeatedly contract and relax.

When the parathyroid glands release more parathyroid hormones, it causes the bones to release more calcium into the blood and reduces the amount of calcium released by the kidneys.

Not exact matches

It Is a great source of saturated fat which helps with cardiovascular health, weight loss, absorption of calcium, liver health, nerve signaling (which helps with metabolism and insulin release), supports the immune system, brain and lungs!

The reason is that cow's milk has a different caloric balance as well as more minerals than human milk, according to Frank Greer, professor of pediatrics at the University of Wisconsin and a co-author of the academy's new guidelines on calcium, which will be released Monday.

Ions such as calcium are important because they affect the release of neurotransmitters, the molecules that mediate communication between brain cells,» said Noebels.

«RyR2 is a mutation — we call it «leaky» RyR2 — that increases the normal amount of calcium inside the cell, which, in turn, triggers the release of an increased amount of neurotransmitters.

When elevating calcium ion concentration directly at the presynaptic terminal with the use of caged calcium, cleavage of SNAP - 25 by botulinum toxin A (BoNT / A) produced a strong reduction in the calcium sensitivity for release, whereas cleavage of syntaxin using BoNT / C1 and synaptobrevin using tetanus toxin (TeNT) produced an all - or - nothing block without changing the kinetics of remaining vesicles.

Volk: Yeah, so Icille was released into Earth's biosphere at the same time Dave was, from a limestone, from the calcium carbonate of a limestone cliff in the Dordogne valley of southern France about the same time that we have the earliest, very earliest cave art in the human prehistory; but Icille didn't last very long in the biosphere, she got trapped in this ice core.

The team found that the main calcium influx pathway involved in the mineralization of enamel [called the CRAC (Ca2 + release - activated Ca2 +) channel — the main type of SOCE (Store - operated Ca2 + entry) channel — is critical for controlling calcium uptake, which is necessary for the development of tooth enamel.

Instead, following exposure to chemotherapy, GSTO1 binds to a protein called the ryanodine receptor 1, or RYR1, that triggers the release of calcium, which causes a chain reaction that transforms ordinary breast cancer cells into cancer stem cells.

Voltage-gated calcium channels can not form properly when cacophony is mutated, preventing fusion of the synaptic vesicle with the plasma membrane and neurotransmitter release.

But making it releases carbon from burning fuel, needed to heat a mix of limestone and clays to 1,450 degrees Celsius (2,642 degrees Fahrenheit)-- and from the heated limestone (calcium carbonate) itself.

PKA phosphorylates IP3 receptors located on cell membranes, inducing them to release intracellular stores of calcium ions.

This released the store of calcium that the spore had been harboring inside itself, and increases the local level of the nutrient even further.

After separation of the solid fraction, the released phosphate dissolved in the liquid fraction can be precipitated as magnesium ammonium phosphate and calcium phosphate, which in turn are directly usable as high value fertilising salts.

Stimulating the plant, such as by touch or wind pressure, triggers the release of this calcium into the main body of a cell, where sensitive calcium receptors register the nature of the stimulus and mount a biochemical response to it.

They report this month in the Proceedings of the Royal Society B that changes in the heartbeat due to temperature (the heart slows as it cools and then speeds back up as the fish resurfaces) and adrenaline, released from the stress of diving, alter the electrical activity of the heart cells to sustain the constant calcium cycling needed to keep the heart going.

Astrocytes also form their own long - distance communication networks by «talking» via waves of calcium ions, and, like neurons, they can receive and release neurotransmitters.

This regulation is spectacularly apparent in the exquisite speed and precision of synaptic exocytosis, where synaptotagmin (the calcium - ion sensor for fusion) cooperates with complexin (the clamp activator) to control the precisely timed release of neurotransmitters that initiates synaptic transmission and underlies brain function.

The findings, Sweeney says, suggest that medications that block the release of excess calcium — which further stimulates contractions and prompts new growth — will lessen the effects of any of these genetic defects.

While most cases of osteoporosis are caused by normal aging, another leading cause of the bone - loss disease is a condition called hyperparathyroidism, in which the parathyroid glands release an excessive amount of a hormone that regulates the body's calcium levels.

This leads to too much of the hormone PTH being released which is likely to lead to a greater risk of calcium and phosphate from the bone damaging the arteries.

The findings reveal a causal chain of events whereby the decreased levels of wolframin protein destabilize the endoplasmic reticulum (causing endoplasmic reticulum stress), thereby reducing calcium release.

Researchers have used this strategy to probe how cells react to the sudden release of signalling molecules, such as the neurotransmitter glutamate and calcium ions.

Once water penetrates the concrete, the microorganisms become active and release calcium carbonate, one of the main components of concrete.

«Bacterial and host cell proteins interact to regulate Chlamydia's «exit strategy»: New research suggests major role for calcium ion signaling in release of Chlamydia from infected cells.»

Calcium entry can spark the release of neurotransmitter packages in less than a millisecond.

As these deposits piled up on the sea floor, rapid chemical changes released massive amounts of calcium, magnesium and phosphorus into the ocean.

Second, Südhof pioneered the use of genetically modified mice to examine the functional role of these skey proteins and the machinery that regulates the calcium mechanism of neurotransmitter release.

They showed that endocrine disruptors — applied at concentrations measured in body fluids — directly open CatSper and, thereby, increase calcium levels in sperm, change their swimming behavior, and trigger the release of digestive enzymes that help sperm to break through the egg coat.

«The combination of fast calcium pumping and small calcium release permits the midshipman to maintain the correct balance of calcium ions during its long - lasting mating call,» Rome says.

A subsequent collision between Antarctica and Africa raised more mountains and released more sediment from 530 to 510 million years ago may have led to the Cambrian Explosion, when most major groups of animals evolved (including trilobites and bivalves which used abundant calcium to build protective carbonate shells).

This tiny all - rounder produces considerable amounts of biomass and calcite — a relatively stable form of calcium carbonate — and releases a climate - cooling gas.

The calcifying alga Emiliania huxleyi produces a considerable amount of biomass and calcium carbonate, supports the ocean's function as a carbon dioxide sink and releases a climate - cooling gas.

Role of initial protein phosphorylation events and localized release - activated calcium influx in B cell antigen receptor signaling.

Inhibition of both oxytocin - induced contraction and calcium release by the traditional NAADP - signaling disrupter bafilomycin and the NAADP receptor antagonist Ned - 19 clearly demonstrated a role for NAADP in oxytocin - induced signaling.

Release of intracellular calcium stores facilitates coxsackievirus entry into polarized endothelial cells.

Abstract T - type calcium channels are key contributors to neuronal physiology where they shape electrical activity of nerve cells and contribute to the release of neurotransmitters.

Autocrine motility factor / phosphoglucose isomerase regulates ER stress and cell death through control of ER calcium release.

Regulation of inositol 1, 4, 5 - trisphosphate receptor - mediated calcium release by the Na / K - ATPase in cultured renal epithelial cells.

A cell - permeant form of NAADP was able to produce both uterine contractions and calcium release.

Bartonella - induced endothelial cell proliferation is mediated by release of calcium from intracellular stores.

The accumulation of calcium can then regulate the contraction of muscles, trigger the release of neurotransmitters or hormones, modulate intracellular signaling pathways, and impact several other calcium - dependent cellular functions.

He discovered that one of the vesicle membrane proteins, synaptotagmin, had separate calcium and phospholipid binding domains, suggesting it had a key role in transmitter release.

When the gel is stretched, some of these bonds between chains break — or «unzip,» as the researchers put it — releasing the calcium.

Südhof then made use of the emerging power of mouse genetics to delineate the functional role of a number of these vesicle proteins including the role of synaptotagmin, which he demonstrated to be the critical calcium sensor for rapid neurotransmitter release.