Sentences with phrase «of celecoxib»

A new CVM study will determine the effectiveness of a novel method of sustained ocular release of celecoxib, an anti-inflammatory medication that can decrease ocular inflammation and eliminate «after - cataract».

The lenses, which provide a sustained release of celecoxib, were developed by the NC State Ophthalmic Research Laboratory under the guidance of Dr. Brian Gilger, a CVM professor of ophthalmology.

Not exact matches

For 24 weeks, 1,583 participants in the aptly named GAIT (Glucosamine / chondroitin Arthritis Intervention Trial) were given one of the following treatments: glucosamine, chondroitin sulfate, both in combination, a placebo, or the COX - 2 inhibitor Celebrex (celecoxib) as a control.

Seventy - eight percent of the patients in the celecoxib group experienced at least a 50 percent reduction in their depression scores, with 63 percent reporting their depression had gone away completely.

Ibuprofen is associated with increased blood pressure and hypertension compared to celecoxib in patients with osteoarthritis or rheumatoid arthritis and increased risk of cardiovascular disease, according to late - breaking results from the PRECISION - ABPM study presented today in a Hot Line Session at ESC Congress1 and published in EHJ.

«Patients receiving ibuprofen had a 61 % higher incidence of de novo hypertension compared to those receiving celecoxib,» said Professor Ruschitzka.

PRECISION - ABPM, 3 a pre-specified four month substudy of the landmark PRECISION trial, 4 was designed to determine the blood pressure effects of the selective COX - 2 inhibitor celecoxib compared to the non-selective NSAIDs naproxen and ibuprofen.

Principal investigator Professor Frank Ruschitzka, professor of cardiology and co-head, Department of Cardiology, University Heart Centre, Zurich, Switzerland, said: «PRECISION - ABPM showed differential blood pressure effects between the different NSAIDs, ibuprofen and naproxen, and the COX - 2 inhibitor celecoxib.

An additional analysis showed that the percentage of patients with normal baseline blood pressure who developed hypertension5 was 23.2 % for ibuprofen, 19.0 % for naproxen and 10.3 % for celecoxib (odds ratio [OR] 0.39, p = 0.004 and OR 0.49, p = 0.03 for celecoxib versus ibuprofen and naproxen, respectively).

The resulting difference of -3.9 mmHg between celecoxib and ibuprofen was significant (p = 0.009).

The treatment was even more effective when combined with celecoxib, a COX - 2 non-steroidal anti-inflammatory drug already approved for treating some forms of arthritis and pain.

A significantly higher amount of stem cells had survived and integrated into the wound tissue in mice that had received celecoxib, and there were fewer inflammatory white blood cells and lower levels of cytokines in their wounds, including one cytokine called interleukin - 17A.

A landmark 2016 Cleveland Clinic study of widely used pain - relieving drugs showed that celecoxib (Celebrex) was associated with comparable cardiovascular safety and better gastrointestinal (GI) and kidney safety when compared...

In another published 12 - week human study, the combination of BCM - 95 curcumin and standardized boswellia (sometimes called frankincense) was compared to the generic of the prescription drug Celebrex (celecoxib) for osteoarthritis of the knee.

It appears to be comparable to celecoxib (an NSAID) with at least one study suggesting that the combination of boswellia and curcumin is more effective.

This resulted in a higher absolute number of aggressive prostate cancers in the dutasteride group than in the placebo group — even though the placebo group had a higher rate of prostate cancer.141 Thus, as we have seen elsewhere, e.g., rofecoxib (Vioxx ®), celecoxib (Celebrex ®), balance in biological processes is more beneficial than absolute interruption.)

This resulted in a higher absolute number of aggressive prostate cancers in the dutasteride group than in the placebo group — even though the placebo group had a higher rate of prostate cancer.145 (See above «Mechanisms through which 5α - reductase inhibitors promote prostate cancer»)(Neal, please make this a link to this section above) Thus, as we have seen elsewhere, e.g., rofecoxib (Vioxx ®), celecoxib (Celebrex ®), balance in biological processes is more beneficial than absolute interruption.)

In this study, special intraocular lenses containing celecoxib will be implanted in the eyes of dogs undergoing cataract surgery.