Sentences with phrase «of cell attachment»

Another limitation observed with microcarriers is the difficulty to efficiently dissociate cells following cell expansion due to the strength of cell attachment to the micro ¬ carriers.

Not exact matches

Obama's elevation of bodily suffering above all other considerations, as he articulates it in his remarks to the press following his new executive order on stem cell research, is clearly an expression of this Cartesian legacy, of a modern science pregnant with moral attachments.

PS extracts block attachment of virus particles to host cells and thus effectively prevent the virus from invading cells.

The back - and - forth attachment and removal of methyl groups also fine - tunes gene expression in stem cells, which can mature, specialize and multiply to become muscle, bone, nerve, or other cell types.

Previous studies have suggested a function of this protein in enamel mineralization and cell attachment.

The structure of mature Zika virus is similar to other flaviviruses, except in the region of a potential cell attachment site.

However, compared to other avian influenza viruses, the attachment to epithelial cells by H7N9 in the bronchioles and alveoli of the lung was more abundant and the viruses attached to a broader range of cell types.

The carbohydrate moiety associated with this residue, which is recognizable in the cryo - EM electron density, may function as an attachment site of the virus to host cells.

A third notable finding was a more concentrated attachment of H7N9 viruses in ciliated cells of the nasal concha, trachea, and bronchi, suggesting the potential for efficient transmission among humans.

Lütolf's lab found that this attachment itself is immensely important for growing organoids, as it triggers a whole host of signals to the stem cell that tell it to grow and build an intestine - like structure.

Its attachment to blood vessel walls might be influenced by the electric polarity of cells there, note Liu, of the University of Washington in Seattle, and colleagues from Washington and Boston University.

«Our study shows that the ability of malaria parasites to engage red blood cells is driven by an ancient mechanism for cellular attachment,» said lead author Aditya Paul, a postdoctoral researcher at the Harvard Chan School.

Cells were then seeded in 96 - well Ultra-low attachment plates (Corning) as a density of 500 per well.

Specific attachment of covalently modified aqueous - based microcapsules to macrophages, B cells, and dendritic cells.

D, the same primary breast cancer cells infected with KLF4 or control lentivirus were cultured in low - attachment plates and the number of mammospheres was counted after 10 days.

Both actin and myosin inhibitors affect spindle architecture in PtK 1 cells: does an actomyosin system contribute to mitotic spindle forces by regulating attachment and movements of chromosomes in mammalian cells?

The SPD genes, some of them known to mediate host - cell attachment, modification of host immunity and immune evasion, frequently presented copy number variations across strains or were found amplified in tandems forming gene arrays.

Laminin - 111 is important during early epithelial development and differentiation of the epiblast, and is commonly used as a general attachment protein in cell culture.

Single cell suspension of HCT - 116 was plated in 6 well ultra-low attachment plates in serum deprived conditions in 37 °C incubator with 5 % CO2.

The dime sized silicon chip TNT attachment to the affected area on the skin converts healthy skin cells into muscle cells; TNT transmission of genetic codes to the skin help heal the injury.

These agents disrupt the microtubule cytoskeleton, thereby inhibiting the attachment of chromosomes to the mitotic spindle and activating the spindle assembly checkpoint (SAC), a surveillance mechanism that delays the progression of cell division.

Since the two poles are on opposite sides of the cell, such a «bipolar» attachment allows the cell to drag each sister to opposite sides as soon as the linkages are removed.

In the past, Naira has investigated bacterial mating of Bacillus subtilis and Clostridium difficile attachment to intestinal cells.

Cancer can develop not just because of changes in the types and amounts of proteins present in a cell but also due to changes in how those proteins are modified — for example, by attachment of sugars (glycosylation).

Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen synthase kinase 3; HD, Huntington's disease; hiPSC, human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R, Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting

It's interesting in light of this variability that for the past 25 years the scientific community has been forced to use just one commercial ECM matrix formulation for cell attachment.

By blocking the binding sites used by HSV - 1 and HSV - 2 for cell attachment, sulfated polysaccharides help prevent replication of these viruses.

The intestinal lining of people with Crohn's disease and IBS (irritable bowel syndrome) appear to be more sensitive to the effects of food lectins because the lining is constantly being replaced by new tissue that is made up of immature cells that are more glycosylated and thus more susceptible to lectin attachment.

The white blood cells will release their enzymes to destroy the bacterial invaders, but will also damage the attachment of the tooth.

In the C - terminus, missense mutations in residues ranging from positions 342 to 452 are thought to inhibit the attachment of ColQ to the basal lamina of the muscle cell [30]--[33].

However, the lure of instant information is an unhealthy attachment and cell phone addiction is real.

The article's authors found that people with anxious attachment styles reported higher levels of cell phone conflict than those with less anxious attachment styles and that phubbing indirectly impacted depression through relationship satisfaction and, ultimately, life satisfaction.

Involvement of P Glycoprotein from Human R7 Cells Derived from Erythroleukemia in Its Attachment to the Progesterone Binding Site

Finally, study 11 extended the findings to a field setting (i.e., a shopping mall), showing that people's perceived crowdedness significantly predicted their attachment to the brand of cell phone they were using.

The chi - square test for attachment style and the adjective violent had counts less than 5 in 50 % of cells; therefore this result must be treated with caution (see Table 6).