Normal anatomical structure and the expression
of cell class - specific markers does not demonstrate normal cellular function and connectivity.
The expression patterns
of cell class - specific markers in mosaic retinas appeared the same in host and donor derived regions suggesting that donor cells generated all retinal cell classes in approximately normal ratios (Figures 5K — 5N and S2).
Not exact matches
In reality, the lifeform belongs to a separate
class of life known as Archaea, a type
of single -
celled organism that typically thrives in harsh environments.
Biotech giant Gilead Sciences is beefing up its cancer drug portfolio with a $ 11.9 billion deal to buy Kite Pharma, a company focused on a groundbreaking new
class of treatments that turns the body's own immune
cells into targeted blood cancer killers.
«Eben came into the
class with a sample
of agricultural waste and mushroom
cells and asked me what I thought,» he recalls.
Time Warner Cable Business
Class offers data, video and voice services to businesses of all sizes, cell tower backhaul services to wireless carriers and enterprise - class, cloud - enabled hosting, managed applications and serv
Class offers data, video and voice services to businesses
of all sizes,
cell tower backhaul services to wireless carriers and enterprise -
class, cloud - enabled hosting, managed applications and serv
class, cloud - enabled hosting, managed applications and services.
Cambridge, MA — February 6, 2017 — Aura Biosciences, a biotechnology company developing a new
class of therapies to target and selectively destroy cancer
cells using viral nanoparticle conjugates, announced today that the U.S. Food and Drug Administration (FDA) has cleared the investigational new drug application (IND) for the company's lead program, light - activated AU - 011 in ocular melanoma (OM).
Cambridge, MA — December 21, 2017 — Aura Biosciences, a biotechnology company developing a new
class of therapies to target and selectively destroy cancer
cells using viral nanoparticle conjugates, announced today that it closed a $ 30 million Series C financing.
Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new
class of therapies to target and selectively destroy cancer
cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial
of light - activated AU - 011, an investigational, first - in -
class targeted therapy in development for the treatment
of ocular melanoma, a rare and life - threatening disease.
Investigators have repeatedly touted the drug as a potential lynchpin in immuno - oncology, focusing on an enzyme that suppresses the immune
cells Opdivo and a whole new
class of PD - 1 / L1 checkpoints are designed to unleash in an attack on cancer
cells.
@Rachel, Many Atheists are simply trying to counter-act the influence
of Christians in their lives, such as science in science
class, gay marriage, stem
cell research, women's choices on reproduction.
As a medical professional, one would think you'd understand that biological evolution, much like general relativity, quantum mechanics, the germ theory
of disease,
cell theory, plate tectonic theory, etc is a scientific theory and should be taught in science
class based on the preponderance
of evidence that backs it.
As we read this history, the furor over stem
cells was fueled by numerous factors: the near - universal human desire for magic; patients» desperation in the face
of illness and their hope for cures; the belief that biology can now do anything; the reluctance
of scientists to accept any limits (particularly moral limits) on their research; the impact
of big money from biotech stocks, patents, and federal funding; the willingness
of America's elite
class to use every means possible to discredit religion in general; and the need to protect the unlimited abortion license by accepting no protections
of unborn human life.
In the sharing
of Christian experience and mutual reinforcement in the faith the idea has affinities with the Methodist
class meetings
of an earlier day; and when the
cell principle is integrated sufficiently with the rest
of life, it reminds one
of those early Christian groups who «day by day, attending the temple together and breaking bread in their homes,... partook
of food with glad and generous hearts, praising God and having favor with all the people.»
The objects
of his study range from a
class of molecules that have the basic self - duplicating property
of living things, through
cells which suggest purely physical systems, through animals which give increasing evidence
of having minds, to human beings in whom streams
of consciousness seem to involve continual choices
of action, at the opposite pole from control by impersonal laws
of nature.
The beliefs
of others impact even non-believers lives through the laws that they promote, e.g. bans on gay marriage, creationism in science
class, reduced stem -
cell research, abstinence only se.x ed., etc., etc..
l) The main subdivisions
of the
class «societies
of occasions» consist
of the linear or «personally ordered» societies, the familiar example being a stream
of consciousness»
of a single person, and nonlinear societies, such as a tree considered as a colony
of cells.
The «in your face,» noisy proclamations are an attempt to assert the atheist's rights to not be discriminated against via public support
of religion, usually Christianity, e.g. stem
cell research, gay marriage bans, creationism in science
class, etc..
This is a quote that my nutrition teacher shared with the
class and it helps to explain what I am saying: «The cause
of nutrition and growth resides not in the organism as a whole but in the separate elementary parts — the
cells.»
Then he remembered things he learned in psychology
classes: A cluster
of cells in the center
of the brain, the nucleus accumbens, gets dosed with the neurotransmitter dopamine when we do something fun, like have sex or eat a doughnut.
I don't know how old Ian is, but he's old enough to own and operate a
cell phone and text with his mother during art
class, so we can safely assume he's over the age
of, say, nine.
(GlaxoSmithKline has decided to stop marketing ezogabine but other existing drugs that also operate by tweaking potassium channels in brain
cells — or a wholly new
class of compounds — could serve in its place.)
For many people, the fear
of a
class of genetically enhanced people is reason enough not to tinker with the DNA
of the human germline — eggs, sperm, embryos and the
cells that give rise to eggs and sperm.
«The discovery
of this special
class of cells that sit right at the nerve endings where HSV - 2 is released into skin is changing how we think about HSV - 2 and possible vaccines,» said Corey.
Researchers at Swansea, in collaboration with industry, are taking these printable materials and focusing on the challenges
of scalability and stability to develop new
classes of solar
cells.
A viral epitope inserted into the complementarity - determining region 3 (CDR3) loop
of the heavy chain
of a self immunoglobulin (Ig) molecule was generated from the Ig context and was presented by I - Ed
class II molecules to virus - specific, CD4 + T
cells.
For some years now, a new
class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist
of an antibody that binds selectively to the tumor
cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer
cells with the antibody and triggers their death.
The elusive e-mailers, who claim to be part
of a group called the Stem
Cell Research Watch Group, responded to an e-mail from Science saying that they are «a group
of students majoring in biology and often discuss papers that are taught in
class.»
Marta Monteiro and colleagues at the University
of Lisbon, Portugal, studied mice protected from the animal equivalent
of multiple sclerosis by natural killer T -
cells (NKT), a
class of white blood
cell which helps to control the immune system.
A
class of small molecules found in grapes, red wine, olive oil, and other foods extends the life
of yeast
cells by approximately 70 % and activates genes known to extend life span in laboratory animals.
They identified five receptors closely related to a
class of receptor already known to help immune
cells hone in on pathogens and inflammation.
Among the most promising are the ampakines, a
class of compounds that keep glutamate receptors open longer, allowing more
of that critical neurotransmitter to enter the
cell.
In this study, the SIgN team discovered for the first time that the integrity
of p53 affects the production
of a special
cell surface protein called Major Histocompatibility Complex (MHC)
class I. MHC
class I molecules on the cancer
cell surface serve as targets for the immune system.
A new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) has identified a mechanism by which cancer
cells develop resistance to a
class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.
One
class of immunotherapeutic drugs is known as «checkpoint» inhibitors, as they target checkpoints in immune system regulation to allow the body's natural defenses, such as white blood
cells, to more effectively target the cancer.
The researchers discovered that two members
of a
class of ion channels that can sense a change in temperature were present in neural crest
cells from chickens and mice.
Immunologist Ralph Steinman was honored today by the Nobel Committee for his discovery
of dendritic
cells, a
class of immune
cells that help rally the body's natural defenses to fight disease.
«Cancer therapies that attack the lipid composition
of the
cell membrane would be an entirely new
class of anticancer drugs,» says co-senior study author Paul Beales,
of the University
of Leeds in the UK.
Additional experiments revealed that a
class of immune
cells, T helper type 2 (Th2)
cells, that many consider critical to triggering asthma prompted levels
of the chitinase enzyme to soar.
Without the worry
of trying to keep a
cell alive, this process opens up many possibilities, including the synthesis
of new
classes of enzymes, therapeutics, materials, and chemicals with diverse chemistry.
The most potently affected
class of immune
cells was plasmacytoid dendritic
cells, known to affect the function
of regulatory T -
cells and the secretion
of interferons, naturally occurring proteins that fend off viruses.
«Because we observed microbial effects mainly in the gut, we believe that a microbe - based therapy would avoid the collateral damage seen with drugs that wipe out
classes of immune
cells across the body,» said Benoist, a professor
of microbiology and immunobiology at HMS.
They also found that saliva contains another
class of small RNAs, called piwi - interacting RNAs, or piRNAs, which are produced by stem
cells, skin
cells and germ
cells.
«Novel capping strategy improves stability
of perovskite nanocrystals: Study addresses instability issues with organometal - halide perovskites, a promising
class of materials for solar
cells, LEDs, and other applications.»
A key factor in the process may be enteric glial
cells (EGCs), a
class of cells that exist in the gut.
USE it or lose it: a
class of immune
cell demolishes idle circuits and connections in the brain, even a healthy one.
Called a medusoid, after the umbrella - shaped
class of jellyfish it mimics, the silicone cyborg uses heart muscle
cells from a rat to recreate the pumping motion
of the moon jellyfish, Aurelia aurita.
Soon he and Janeway discovered a new
class of sensor on the surface
of a certain kind
of immune
cell.
In
Class I engagement, Sox9 binds to the genome indirectly via the basal transcriptional complex, regulating transcription
of genes for basal
cell activities.
Different
classes of MHC molecules exist and are involved in immunity against pathogens and tumor
cells as well as the formation
of immune tolerance to self - antigens.