Sentences with phrase «of cell cycle progression»

This study, published recently in PLOS Genetics, shows that in the particular case of meiotic cells such as spermatocytes, the signalling route of the ATM protein also participates in the control system of the cell cycle progression in response to DNA damage, something which until now was unknown.

«It completely turns upside - down what was thought to be a fundamental aspect of cell cycle progression in all cancer cells driven by one of the most common genetic pathways mutated in cancer, namely the p16 - cyclin D pathway.»

There are as many as 14, but the scientists found that cyclin D adds just a single phosphate at one, and only one, of the 14 locations during the early G1 phase of cell cycle progression, essentially make 14 different versions of the Rb tumor suppressor.

Palbociclib has been designed to thwart tumor growth by preventing key molecules of cell cycle progression from doing their job.

Ralf Kittler (Buchholz, MPG)-- «Functional genomic analysis of cell cycle progression in human tissue culture cells» (2006)

Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P. Cyclin D1 - Cdk4 controls glucose metabolism independently of cell cycle progression.

Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation.

Validation of a cell cycle progression score for five - year mortality risk in patients with stage I lung adenocarcinoma.

Labeling, detection and quantification of cells in the S - phase (DNA synthesis) of cell cycle progression are crucial in characterizing the cellular responses to various treatments and genetic modifications.