Sentences with phrase «of cell cycle regulators»

Maria Anna Ciemerych began her research with studies focusing at the cell cycle regulation of mouse oocytes and preimplantation embryos (Ph.D. at the University of Warsaw), then investigated the role of the cell cycle regulators - D - type cyclins, in mouse development (Dana Farber Cancer Institute, Harvard Medical School).

«This idea fits nicely with the findings from a number of groups — that forced expression of cell cycle regulators can induce cardiomyocyte proliferation in mammals,» says Jopling.

Recently, several RNA helicases, such as RNA helicase A and CHAMP, have been shown to modulate the expression of cell cycle regulator p16INK4a or p21waf1 / cip1 (32, 33).

To address the mechanism of growth inhibition by DDX3, we examined whether the promoter activity and the expression level of the cell cycle regulator p21waf1 / cip1 are regulated by DDX3.

Not exact matches

Igoshin said that when the researchers set out to find how sporulation decisions were timed to the cell cycle, several studies including prior work by team members, provided a significant clue: Under starvation conditions, the activity of the master regulator gene had been shown to spike once per cell cycle.

But in addition to these factors, Hunt, who won a share of the 2001 Nobel Prize in physiology or medicine (along with Leland Hartwell and Paul Nurse) for his discovery of cyclin, a key regulator of the cell cycle, emphasizes early independence and playfulness.

This led me to enter the field of developmental and cell biology, and to eventually discover cyclin as a key regulator of the cell cycle.

All textbooks describe the cyclin - dependent kinase complex as the one and only / exclusive regulator of the eukaryotic cell cycle.

In 2001 he was jointly awarded the Nobel Prize for Physiology or Medicine for discoveries of key regulators of the cell cycle.

Hsiou - Chi Liou and colleagues find that c - Rel, a lymphoid - specific member of the NF - kappaB / Rel family of transcriptional factors, is essential for B lymphocyte survival and cell cycle progression, [i] and that it is important for inducible cytokine and cytokine receptor expression and a key regulator of early activation and proliferation in T cells.

The cell cycle regulator p21 mediates the ability of the tumor suppressor p53 to arrest cellular proliferation.

ClC3 is a critical regulator of the cell cycle in normal and malignant glial cells.

The cell - cycle regulator c - Myc is essential for the formation and maintenance of germinal centers.

SLIMP is an important regulator of mitochondrial translation that possibly controls the replication status of mitochondria and somehow ties this process to the cell cycle.

Today, we know that the retinoblastoma gene product, the RB protein, is a master regulator molecule of the cell cycle.

All CM members have research interests in basic cancer mechanisms, including the normal functions of oncogenes and tumor suppressor genes; regulators of cell cycle and apoptosis; regulators of angiogenesis and metastasis; and stem cells and blood formation.

These commonly regulated genes clustered into the functional category of cell - cycle regulators.