Sentences with phrase «of cell engineering»

Hence, development of technologies capable of effectively overcoming these barriers for delivery of cell engineering materials, while preserving critical cell functions, is vital to success.

«This paper is a great example of how chemistry can help make step changes in biology,» says Matthew Dalby, a professor of cell engineering at the University of Glasgow and co-senior author on the study with Ulijn.

Nonetheless, for the researchers, «The success of our cell engineering experiments, which make it possible to produce nerve cells in a controlled and unlimited manner, and to transplant them, is a world first.

Not exact matches

When Vancouver civil engineer James Dean started his greentech company, dPoint Technologies, in the early 2000s, he figured he could hitch his wagon to the promise of the hydrogen fuel cell sector.

Brendan Frey, CEO of Deep Genomics and a biomedical engineering professor at the University of Toronto, says his research team trained its system to analyze individual cells to draw conclusions about the entire cellular system and, ultimately, make a diagnosis.

Drawing on his 20 years of engineering experience, Chamtech Technologies founder Anthony Sutera began experimenting and eventually created a liquid composed of nanoparticles, that when dried, could function as a highly efficient antenna — whether painted onto a building or injected directly into the molding of a cell - phone case.

Technology by Cellectis allows cellular engineering, and a human trial of the company's work in editing blood cells will be presented at the upcoming American Society of Hematology.

It is infinitely customizable for a variety of different home styles, each uniquely engineered so that the photovoltaic cells are invisible.

He earned degrees in cell biology and tissue engineering and eventually got a job in a lab run by Vladimir Mironov, who was investigating the use of bioprinting — 3 - D printing using living cells — to generate replacement organs.

The squeeze system Sharei then designed to temporarily disrupt cell membranes — for which he's been granted most of his 10 patents — is the basis for SQZ Biotech, the company he co-founded in 2013 with the pioneering MIT professors he worked for: Klavs Jensen, the school's head of chemical engineering, and Robert Langer, a renowned bioengineer and serial entrepreneur.

But in June, the Chan Zuckerberg Initiative — the philanthropic organization in Palo Alto, California, that funds the Biohub — contributed an undisclosed amount of money and software - engineering support to the Human Cell Atlas data platform, which will be used to store, analyse and browse project data.

In the second half of 2017, the United States Food and Drug Administration (FDA) approved two immunotherapies that use genetically engineered T cells (CAR - T cell therapy) to fight cancer.

We had two entrepreneurs in the cell phone industry, a Business Broker, a Hedge Fund Manager, Managers of a Trust, a Business Appraiser, an Engineer, a Financial Planner, a Bar and Grill Owner, a Computer Software Executive, A Nurse RN, an Equities Analyst, a Wine Vineyard owner, and a former Mortgage Broker.

Most foam crib mattresses have only a very small degree of breathability, but Colgate uses high quality, open cell foam and PE foam engineered with air channels to enhance circulation.

The National Transportation Safety Board is seeking to obtain cell phone records of the teenager and the engineer, said Kitty Higgins, a member of the board dispatched to the scene.

The Chief of Army Staff, Lt Gen Tukur Yusufu Buratai has inaugurated the Multi — Cell box culvert linking Shema — Bakoshi — Matankari towns in Zuru local government Area of Kebbi State which was constructed by Army Engineers.

Planning board chairman Drew Boggess, a Rotron engineer and manager, was nominated by his wife Judith and again seconded by Horner, who noted his background as someone familiar with technical aspects of modern life... a theme quietly played out over the evening as some noted Rozzelle's unfamiliarity with and distaste for voice mail, cell phones and email.

In experiments with mice, the researchers found that Paneth cells engineered to lack a functional ATG16L1 gene were five times more likely to die in the face of rising TNF - alpha signals than normal cells.

Carlos Filipe, a chemical engineer at McMaster University in Hamilton, Canada, and colleagues have developed a new kind of flexible film that's coated in molecules that glow when they touch E. coli cells.

An implant of genetically engineered skin cells has been designed to grow darker in colour when it detects early breast, prostate and colon cancers

The implant, made of genetically engineered cells, has been designed to detect developing breast, prostate and colon cancers when they are only a few millimetres in size.

The essays represent a wide range of scientific topics: neuroscience, biology, «Big Data», forensic anthropology, science policy, STEM education, wildlife ecology, environmental sustainability, sociology, medicine, global health, science ethics, stem cell research, materials engineering, crowd - sourcing, computer science, biotechnology, genetics, agricultural sciences, climate change, and information technology.

The goal of synthetic biology, which combines biology with engineering, is to (re) program cells in order to improve their performance in a specific task, or so that they can efficiently perform a new task.

The design and formation of an atomic - scale bridge between different materials will lead to new and improved physical properties, opening the path to new information technology and energy science applications amongst a myriad of science and engineering possibilities — for example, atoms could move faster at the interface between the materials, enabling better batteries and fuel cells.

The scientific breakthrough that we made early — that attracted Exxon — we engineered [a] cell to pump hydrocarbons out of the cell.

The new technology, described in the journal Molecular Cell, offers a new way to seek drug targets for many diseases, not just Parkinson's, says Timothy Lu, an MIT associate professor of electrical engineering and computer science and of biological engineering.

Some of the other projects involve the development of proton exchange membrane for fuel cell application, a gyroscope based on micro-electromechanical technology and research on innovative engineering materials to fabricate ceramic membranes that can partially oxidize methane to syngas used as feedstock in commercial methanol production.

Now that they've shown it's possible to encode and retrieve information sequentially in bacteria, Shipman hopes to create «molecular recorders» — genetically engineered cells with a time log of their activities.

«This research represents an important step toward the goal of being able to better treat thyroid diseases and being able to permanently rescue thyroid function through the transplantation of a patient's own engineered pluripotent stem cells,» explained co-corresponding author Anthony N. Hollenberg, MD, Chief of the Division of Endocrinology, Diabetes and Metabolism at BIDMC and Professor of Medicine at Harvard Medical School.

The discovery, published today in Cell, came about when postdoctoral fellow Akhila Rajan of Harvard Medical School in Boston and her adviser, Norbert Perrimon, engineered flies that lacked a nutrient - sensing protein called Upd2.

By using engineered zinc - finger nucleases (ZFNs) designed to target an integrated reporter and two endogenous rat genes, Immunoglobulin M (IgM) and Rab38, we demonstrate that a single injection of DNA or messenger RNA encoding ZFNs into the one - cell rat embryo leads to a high frequency of animals carrying 25 to 100 % disruption at the target locus.

They'd be transformed by synthetic biology, a young field of engineering that crafts building materials from DNA and cells rather than more traditional biological materials, like trees.

In an amazing feat of tissue engineering, Anthony Atala and his research team at the Children's Hospital in Boston are creating new organs in the laboratory using patients» own cells and by employing the same technology used to clone Dolly the sheep.

On to the blocks were poured a mixture of recombinant human bone morphogenic protein (BMP) powder — a genetically engineered protein that causes cells to ossify or become bone — and liquid bone marrow containing stem cells.

Then, to boost the number of cells, which is another hurdle in tissue engineering, the researchers mixed the chondrocytes with human mesenchymal stem cells from bone marrow.

Cells engineered to produce insulin under the command of a smartphone helped keep blood sugar levels within normal limits in diabetic mice, a new study reports.

«The placement of the pegs that this group of cells wraps itself around and then exerts force on each other is what dictates their alignment and the direction of the ECM they are going to synthesize,» said senior author Jeffrey Morgan, professor of medical science and engineering and co-director of Brown's Center for Biomedical Engineering.

To hunt for drugs that target these cells, Piyush Gupta, a molecular biologist at the Broad Institute at the Massachusetts Institute of Technology, and colleagues genetically engineered ordinary human cells so that they acquired some of the properties of cancer stem cells, including being impervious to chemotherapy.

Jürgen Hauer, a co-author of the report and a junior research group leader at the Photonics Institute of the Vienna University of Technology, explained that natural systems have evolved to use light efficiently, but there are some caveats before engineers can design a solar cell that works as effectively as a leaf.

Dr. Llovet and colleagues demonstrated that the expression of mutant IDH in the adult liver of genetically engineered mice impairs liver cell development and liver regeneration — a process in which the liver responds to injury — and increases the number of cells to form a tumor.

To solve this problem, Smadar Cohen, a tissue engineer at Ben - Gurion University of the Negev in Beersheba, Israel, and colleagues seeded rat cardiac cells onto scaffolds which they transplanted into the omentums of eight rats.

Engineers are well - equipped to sketch so - called wiring diagrams of biochemical pathways that lead to aberrant cancer cells.

Defined as the harnessing of living processes to achieve healing and repair of damaged and diseased tissues by Tim Hardingham, director of the UK Centre for Tissue Engineering, it is a field that requires collaborative research involving cell and molecular biologists, chemical engineers, materials scientists, and surgeons.

Being able to engineer organs using a patient's own cells can not only alleviate this shortage, but also address issues related to rejection of donated organs.

Dr. Zubair is working with engineers at the University of Colorado who are building the specialized cell bioreactor that will be taken to the ISS within a year for the experiment.

They use a near - infrared laser beam, which can penetrate deep — in this context, deep means a centimeter or two — into the tissue, where a nanoparticle turns the near - infrared light into blue light, and that directs the activity of genetically engineered immune cells.

Tissue engineering provides a more practical means for researchers to study cell behavior, such as cancer cell resistance to therapy, and test new drugs or combinations of drugs to treat many diseases.

However, some mice experienced dangerous levels of brain swelling, a side effect of the immune response triggered by the engineered cells, the researchers said, adding that extreme caution will be needed to introduce the approach in human clinical trials.

Above all, synthetic biology «requires a new way of thinking about biology: the idea that cells are machines and they can be rebuilt the way that electrical engineers now design circuits [and] instruments,» Glass says.

«This shows iPS cells have a lot of problems, but that doesn't mean they don't have potential — just not with the established methodologies used to create them,» says tissue engineer Anthony Atala, director of Wake Forest University Baptist Medical Center's Institute for Regenerative Medicine in Winston — Salem, N.C. «It's a solvable problem, but it looks as if one should look away from methods that don't genetically modify the cell.»