Sentences with phrase «of cell fusion»

Rat adult stem cells (marrow stromal cells) engraft and differentiate in chick embryos without evidence of cell fusion.

This research reveals a new type of cell fusion that is initiated to destroy a particular cell, and enlightens the evolution of sexual reproduction in flowering plants.

«The frequency of cell fusion events in vivo is not known, although cell fusion is thought to occur under some circumstances such as cell injury, inflammation, and viral infection.

This microscopic image of fibroblast cells shows the induction of cell fusion by a newly described gene and its protein, called myomerger.

Not exact matches

At Key Stage 3 (age 11 to 13 +, Years 7 to 9) schools have to teach: that fertilisation in humans and flowering plants is the fusion of a male and a female cell; about the physical and emotional changes that take place during adolescence; about the human reproductive system, including the menstrual cycle and fertilization; how the foetus develops in the uterus, including the role of the placenta.

Indeed, the ability to clone animals, such as Dolly the sheep, by fusion of an adult cell to an enucleated oocyte demonstrates that the epigenetic programming responsible for maintaining an adult cell in a stable state can be erased by factors present in the cytoplasm of the oocyte.

Cell fusion technology is used to hybridize plants by removing cell walls from two cells of different species, usually those that would not normally breed under natural conditions, and then merging their conteCell fusion technology is used to hybridize plants by removing cell walls from two cells of different species, usually those that would not normally breed under natural conditions, and then merging their contecell walls from two cells of different species, usually those that would not normally breed under natural conditions, and then merging their contents.

Such methods include cell fusion, microencapsulation and macroencapsulation, and recombinant DNA technology (including gene deletion, gene doubling, introducing a foreign gene, and changing the positions of genes when achieved by recombinant DNA technology).»

The second part of this process is the fusion of the polar nuclei with a second sperm cell nucleus, thus forming a primary endosperm.

For example, beyond the cell fusion effects of myomaker and myomerger, it isn't known how myomaker or myomerger induce cell membrane fusion.

Researchers then tested cell cultures and mouse models by using a gene editing process called CRISPR - Cas9 to demonstrate how the presence or absence of myomaker and myomerger — both individually and in unison — affect cell fusion and muscle formation.

One of the mechanisms being studied is reprogramming through cell fusion.

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

Designed for use in spinal fusion surgery of the lower back, Infuse consists of a titanium cage that houses a collagen sponge soaked in bone morphogenetic protein (BMP), a growth factor that signals bone - forming cells to produce new tissue.

Subsequent procedures included mammalian somatic cell nuclear transfer, cell fusion, induction of pluripotency by ectopic gene expression, and direct reprogramming.

After a median follow - up of 11 months, 11 of the 13 patients who responded remain on the study, including one patient who had non-small cell lung cancer (NSCLC) with a ROS1 gene fusion who has had a complete response that has been maintained for more than two years.

Because muscles form through fusion of cells, the examples they found were all formed by fusion.

Published in the March 31 advance online issue of Cell, their findings reveal that circular RNAs — like their protein counterparts — are also affected by genomic rearrangements in cancer, resulting in abnormal fusions.

Cancer cells are notorious for their genomes gone haywire, often yielding fusion proteins — mash - ups of two disparate genes that, once united, assume new and harmful capabilities.

Their findings, published in mBio, an online open - access journal of the American Society for Microbiology, reveal key host cell and viral proteins that direct fusion and Ebola infection.

Cancerous Marriage The fusion of tumor cells with white blood cells may be the secret behind how cancer spreads around the body.

Next on the team's agenda is to explore molecules that are involved in the fusion of synergid cells and endosperm.

What makes it interesting it that it is directly responsible for the fusion of the HIV virus into human cells.

Their study is only the third report of plant cell fusion being observed and the first observation since the initial reports in the late 1800s.

Five to seven years down the road, he predicts, patients recovering from spinal fusion or joint - replacement operations will have some of their own fat cells removed, processed, and implanted at the same time as other surgical procedures.

Not everybody can do the enucleation and cell fusion process quickly and precisely, and it is likely that the optimization of transfer procedure greatly helped us to achieve this success.»

The human body contains trillions of cells, all derived from a single cell, or zygote, made by the fusion of an egg and a sperm.

He tested various methods to quickly and precisely remove the nuclear materials from the egg cell and promote the fusion of the nucleus - donor cell and enucleated egg.

However, by combining the capabilities of the Surface Forces Apparatus (SFA)-- a device that can measure the tiny forces generated by the interaction of two surfaces at the sub-nano scale — and simultaneous imaging using a fluorescence microscope, the researchers were able to see in real time how the cell membranes rearrange in order to connect and open a fusion conduit between them.

Among these functions is the transport of lipids and other biomacromolecules between cells via membrane adhesion and fusion — processes that occur in many biological functions, including waste transport, egg fertilization and digestion.

The scientists, Nicole King and Arielle Woznica of the University of California, Berkeley, with collaborators Jon Clardy and J.P. Gerdt at Harvard Medical School in Boston, discovered that within minutes after exposure to a chonodroitin sulfate (CS) lyase produced by V. fischeri, S. rosetta cells aggregate into mass mating swarms, entering into cell and nuclear fusion while duplicating and recombining their genetic material.

An abnormal gene created by the fusion of ETV6 and the RUNX1 gene is one of the most common alterations in childhood ALL and is found in the leukemic cells of 20 to 25 percent of pediatric ALL.

«We were able to identify the receptor BAI3, a protein at the surface of myoblasts, as one of the crucial missing links in the fusion of muscle cells,» adds Dr. Côté.

«Making the movements of HIV visible so that we can follow, in real time, how surface proteins on the virus behave will hopefully tell us what we need to know to prevent fusion with human cells — if you can prevent viral entry of HIV into immune cells, you have won,» says Dr. Blanchard, who is also associate director of Weill Cornell's chemical biology program.

«We believe one cell fusion event can both initiate malignancy and fuel evolution of the tumor that ensues,» noted lead author Xiaofeng Zhou, Department of Microbiology and Immunology and Surgery and the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, at the University of Michigan (Ann Arbor).

However, direct evidence that fusion of normal cells by itself could trigger cancer has not been reported.

Furthermore, only those fusion - derived IEC - 6 cell clones that had undergone the changes in cellular growth indicative of neoplastic transformation produced tumors in mice.

Reporting online May 18 in Science, researchers describe a genetic variant that apparently is responsible for the fusion of two proteins that protrude from the membranes of red blood cells.

The finding that normal fertilization can result in embryos containing cells with different parental sets of chromosomes is a new mechanism for chimerism, which was previously thought to occur only as the result of fertilization errors, for example, the fusion of multiple sperm or eggs to form an embryo.

«These results indicate that cell fusion generates chromosomal instability,» explained lead investigator Jeffrey L. Platt, M.D., professor of surgery and microbiology and immunology, Departments of Microbiology and Immunology and Surgery, University of Michigan (Ann Arbor).

Double fertilization of the female gametes triggers an unusual cell fusion, followed by specific cell disorganization that inactivates the cell responsible for attracting pollen tubes.

Cell to cell fusion is known to be extremely rare in plant cells due to the presence of the relatively tough cell wCell to cell fusion is known to be extremely rare in plant cells due to the presence of the relatively tough cell wcell fusion is known to be extremely rare in plant cells due to the presence of the relatively tough cell wcell wall.

Introducing substances into the postsynaptic cell that block membrane fusion at a number of different steps reduced LTP.

«Through examination of Arabidopsis ovules by highly sensitive live - imaging, we were able to see that successful fertilization of the two female gametes triggers an unprecedented cell fusion between the persistent synergid cell and the endosperm (SE fusion), which eventually leads to inactivation of the persistent synergid cell.»

Nagoya, Japan — Dr. Daisuke Maruyama and Professor Tetsuya Higashiyama at the Institute of Transformative Bio-Molecules (WPI - ITbM) of Nagoya University and the JST - ERATO Higashiyama Live - Holonics Project along with their international team have shown by live - cell imaging techniques that flowering plants, such as Arabidopsis thaliana undergo a cell to cell fusion to prevent the attraction of the second pollen tube after fertilization has occurred.

In a new study reported in Cell, an international group of plant biologists at ITbM, Nagoya University and other research institutes, have examined the ovules of plant cells by live - imaging to reveal a novel cell - elimination system based on an unusual cell fusCell, an international group of plant biologists at ITbM, Nagoya University and other research institutes, have examined the ovules of plant cells by live - imaging to reveal a novel cell - elimination system based on an unusual cell fuscell - elimination system based on an unusual cell fuscell fusion.

Consequently, this research reports the third plant cell fusion event that was identified during normal developmental processes of flowering plants.

The study, published online on April 23, 2015 in the journal Cell, outlines the complicated mechanism of communication between plant cells, where an unusual cell fusion induces selective elimination of the cell responsible for pollen tube attraction after successful fertilizatCell, outlines the complicated mechanism of communication between plant cells, where an unusual cell fusion induces selective elimination of the cell responsible for pollen tube attraction after successful fertilizatcell fusion induces selective elimination of the cell responsible for pollen tube attraction after successful fertilizatcell responsible for pollen tube attraction after successful fertilization.

A continuous cytoplasm between the persistent synergid cell and the endosperm was also observed, providing evidence for fusion of the two cells.

A new strategy for engineering protein fusions — to make specific cell - targeted drugs without side effects — could enable a safer, more potent class of protein drugs.