Sentences with phrase «of cell injury»

Topics such as the mechanisms of cell injury in normal and dystrophic muscle, compensatory muscle regeneration and hypertrophy, and the effects of various therapies or voluntary exercise on muscle repair, satellite cell activation, muscle growth, bone density and age - related atrophy are examined using a large variety of cellular, molecular and whole - animal in vivo assays of function.

Not exact matches

Social media buzzed with reports of players who suffered minor injuries from tripping and falling while glued to their cell phones and minor incidents while driving and looking for Pokemon.

According to the report, the team member who went in to the brothel as a decoy customer was beaten and robbed of his cell phone and cash, but escaped with the girl without further injury.

Duly reverential, the panel satisfied itself with simply listing all the research possibilities, including the improvement and increased safety of IVF, the creation of cell lines that might someday be useful for bone marrow transplantation, repair of spinal cord injuries, skin replacement and, naturally, the hint of a greater understanding of cancer.»

In addition, affected individuals may heal slowly from injuries or have frequent infections due to the loss of normal white blood cells that fight infection.

The study, «Polarity of varicosity initiation in central neuron mechanosensation,» which will be published June 12 in The Journal of Cell Biology, observes the swelling process in live cultured neurons and could lead to new ways of limiting the symptoms associated with concussive brain injuries.

Jaundice which is due to the rapid, abnormal destruction of the baby s blood cells often resulted, in the past, in serious injury or even death for the baby, but this is different from what most babies are now experiencing.

It can lead to substantial injury to the mother's liver, a breakdown of her red blood cells, and lowered platelet count,» Eleni Tsigas, Chief Executive Officer of the Preeclampsia Foundation, explains to Romper.

Cord blood stem cells can be used to treat dozens of diseases and are being tested in FDA - regulated clinical trials to help people with autism, brain injury, and other conditions.

Joel Feldman with the Casey Feldman Foundation notes that New York State already bans both hand held calls and texting while driving, but he says three quarters of all distracted driving injuries and deaths are unrelated to cell phones.

The Regenerative Research Foundation in Rensselaer, an affiliate of the Neural Stem Cell Institute, will receive nearly one - fifth of the funds, or almost $ 1.1 million, for work aimed at promoting spinal cord regeneration after injury.

Roman Giger, an associate professor of cell and developmental biology at the University of Michigan, Ann Arbor, studies neurodegeneration and treating spinal cord injury.

«It turns out cells have a number of different ways to signal injury.

Most groups have focused on detecting proteins released from dying brain cells, but those proteins are not always abundant after injury and often require exotic or proprietary antibodies to measure, said study corresponding author Adam Chodobski, associate professor (research) of emergency medicine in the Alpert Medical School of Brown University.

Q: Is there some connection to be made between the responses of cells encountering stress or injury versus a whole person?

It goes beyond the structure of life and gets to biological processes, including how cells or molecules move, how cells respond to their environment or neighbors, and how the brain works or how injuries heal, he says.

They discovered that in the young, more immune cells called monocytes were recruited to the lungs, and that the gene expression profiles of these cells had more inflammatory features, causing greater inflammation and more severe lung injury.

The decision was seen as an effort to mollify the religious fundamentalists at the core of Bush's political support who are ideologically opposed to deriving the cells from frozen embryos in fertility clinics and scientists and patients who hope that the cells could be used to help patients with Parkinson's, Alzheimer's, spinal - cord injuries, and diabetes.

The clinical trial is designed to assess safety and activity of escalating doses of the special cells (AST - OPC1) for individuals with a complete cervical spinal cord injury.

Large quantities of these reverted cells could be used to treat anything from spinal cord injury to liver damage without the risk of tissue rejection, said Robert Weinberg, a biologist at the Massachusetts Institute of Technology's Whitehead Institute for Biomedical Research and co-author of a study appearing in Cell.

In the new study, Zigmond and colleagues found damaged nerve cells produce a stream of molecular lures that specifically attract neutrophils to injury sites in mice.

A new kind of cellular alchemy may allow cells to be converted into other tissues to treat injuries.

This knowledge is important, as iPSCs hold great promise in the field of regenerative medicine, as they can provide a single source of patient - specific cells to replace those lost to injury or disease.

Researchers at Rush University Medical Center are exploring a new therapy using stem cells to treat spinal cord injuries within the first 14 to 30 days of injury.

To test the cells» abilities, the researchers injected them into the injured body parts of rodents with diabetes or injuries that cut off blood flow to the retina, heart or hind leg.

«There are currently no therapies which successfully reverse the damage seen in the more than 12,000 individuals who suffer a spinal cord injury each year in the United States alone,» says Dr. Richard G. Fessler, professor of neurological surgery at Rush University Medical Center and principal investigator for the Phase 1 clinical trial involving AST - OPC1 (oligodendrocyte progenitor cells).

So Daniel Anderson at the Massachusetts Institute of Technology exposed human bone marrow stem cells to biodegradable nanoparticles carrying the human gene for vascular endothelial growth factor (VEGF), which attracts blood vessels to injury sites.

Scientists at the Medical College of Wisconsin (MCW) have discovered a link between sleep loss and cell injury.

When RCGD 423 was applied to joint cartilage cells in the laboratory, the cells proliferated more and died less, and when injected into the knees of rats with damaged cartilage, the animals could more effectively heal their injuries.

Disease or an injury to the retina also can cause the loss of protective proteins in the cells, resulting in additional cell death.

Dr. Llovet and colleagues demonstrated that the expression of mutant IDH in the adult liver of genetically engineered mice impairs liver cell development and liver regeneration — a process in which the liver responds to injury — and increases the number of cells to form a tumor.

«We came up with a list of potential cellular candidates that could be compensating for the loss of these specific macrophages and used several different tests to determine which cells were clearing away the nerve debris after injury,» Lindborg said.

Small populations of adult stem cells with somewhat limited developmental potential are responsible for the body's ability to heal injuries and replace worn out cells and tissues, and evidence is growing that rare cancer stem cells are responsible for the uncontrolled growth of some malignant tumors, including glioblastoma.

But in disease conditions like muscular dystrophies, satellite cells can't keep up with repeated cycles of injury and are ultimately exhausted or functionally impaired,» Hindi said.

When muscle injury occurs, a complex chain of signals prompts the satellite cells to awaken and generate new muscle cells to repair the injury.

They then argue that «By creating a financial incentive for embryonic stem cell research — an incentive that by NIH's own admission involves investments of «hundreds of millions of dollars» — and by specifying the precise means by which embryos must be destroyed in order to qualify for federal funding, the NIH necessarily and knowingly subjects embryos to a substantial risk of injury or death.»

Studying mice with injuries to the lining of the stomach, the researchers blocked the animals» ability to call on stem cells for help in the stomach.

The findings suggest that damage to brain cells called interneurons disrupts neurotransmitter levels and plays a role in the development of epilepsy after a traumatic brain injury.

The research, published in the current issue of the journal Science, demonstrates that brain cells, known as astrocytes, which play fundamental roles in nearly all aspects of brain function, can be adjusted by neurons in response to injury and disease.

«If we can preserve these important cells, we may be able to decrease the negative impacts of traumatic brain injury,» said first author David Cantu, Ph.D., a postdoctoral scholar at Tufts University School of Medicine, and member of the NIH - funded Institutional Research Career and Academic Development Awards (IRACDA) Program, Training in Education and Critical Research Skills (TEACRS), at the Sackler School of Graduate Biomedical Sciences at Tufts.

Encased in bone and protected by a special layer of cells, it is shielded from infections and injuries — but also from many pharmaceuticals and even from the body's own immune defenses.

Astrocytes are star - shaped cells in our brain that surround brain neurons, and neural circuits, protecting them from injury and enabling them to function properly — in essence, one of their main roles is to «baby - sit» neurons.

Scientists can't yet grow spare parts of the human brain to fix neurological injuries or defects, but they have recently used stem cells to create brain organoids, formations of cells that mimic some of the brain's regions.

The hope is that these progenitor cells, codenamed GRNOPC1 cells, will help the patient overcome paralysis resulting from the injury, although the primary objective of the trial is to make sure the treatment is safe.

In humans, the goal of SCNT is «nonreproductive cloning» — making embryos, then removing stem cells from the embryo and cultivating them to grow into tissues that could cure diseases, replace organs and heal injuries.

Working in Morrison's Neurotrauma and Repair Laboratory at Columbia Engineering, the team developed a blast injury model using a shock tube and custom - designed sample receiver to simulate a primary blast event and applied it to an isolated, living model of the BBB that consisted of brain endothelial cells.

«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.

The treatment not only led the spinal cord cells to produce and secrete ChABC in large quantities over areas spanning the injury epicenter, it helped to maintain the overall health of the damaged spinal cord and restored hind limb function in the animals within 12 weeks.

Yonju Ha, a lead author of this article, said that further studies on this receptor and its role in white blood cell recruitment following tissue injury may aid in the development of new interventions for diseases associated with nerve injury, such as TON, stroke, diabetic retinopathy and glaucoma.

Excessive or uncontrolled inflammation can actually make injuries worse and contribute to disease in a couple of different ways — by activating cell death processes, clogging and rupturing blood vessels and producing toxic molecules like free radicals.