Sentences with phrase «of cell interaction»

Not exact matches

The chemical environment of the molecule and the molecule itself are in constant, dynamic interaction, influenced by the magnitude of physical forces and configuration of chemicals within the cell.

Birch and Cobb maintain that the ecological model is more adequate than the mechanical model for explaining DNA, the cell, other biological subject matter (as well as subatomic physics), because it holds that living things behave as they do only in interaction with other things which constitute their environment (LL 83) and because «the constituent elements of the structure at each level (of an organism) operate in patterns of interconnectedness which are not mechanical» (LL 83).

81), but in their effort to refute such a view, I see no effective reason given other than the high level of complexity of interactions in the cell.

Likewise, he can talk about causal interaction between the central series of experiences in the human being (the mind, or psyche) and the bodily cells.

The question is whether, at one extreme, the mind of the Universe is all - knowing and omnipotent, or at the other, it is merely that which is superimposed on the point - to - point interactions of the minds of the components as the integrating factor, in much the same relation as that of my mind to the minds of my cells and lower entities in the hierarchy of existence.

After examining chick and mouse embryos, researchers determined movement stimulates molecular interactions that guide the cells and tissues of an embryo to become functional bones and joints.

The next goal of the researchers is to examine interactions between perovskites and other molecules, for example water molecules that are known to interfere with the performance of solar cells.

The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.

«B - cells are really cool cells,» says immunobiologist Mark Shlomchik of Yale University, who studies the interaction between B - cells and two receptors within them, TLR7 and TLR9.

In a new study, researchers at the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science examined how the interaction of two genomes in animal cells — the mitochondrial and nuclear genomes — interact to affect adaptation of the Atlantic killifish to different temperatures.

In 2004, he joined a Marie Curie Research Training Network of the European Commission, studying the sugar - protein interactions that mediate cell - cell recognition.

Stomach switch The key to turning pluripotent stem cells into stomach cells was a pathway of interactions that acts as a switch between growing tissues in the intestine and in the antrum, a part of the stomach near its outlet to the small intestine.

In Robinson's lab, Sharon studied protein - protein interactions within proteasomes, large multiprotein complexes that clear cells of unwanted proteins by degrading them into small peptide fragments.

Dr Stotz continued: «This concept of plant ETI does not really explain the second line of defense in the interaction of plant hosts protecting themselves against extracellular fungal pathogens — i.e. those foliar fungal pathogens that get into the leaf of the plant to exploit the space between its cells, known as the apoplast, to retrieve nutrients from the plant.

Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interrelationship of DNA, RNA and protein synthesis and learning how these interactions are regulated.

«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.

Markram's model will electronically mirror the real brain's biological behaviors, imitating mathematically the interactions among individual neurons and the effects of neurotransmitters on those cells.

Given these complex interactions, Andreas Meyerhans and Jordi Argilaguet, both from the Pompeu Fabra University in Barcelona, Spain, and colleagues argue that it is important to understand the consequences for Treg cells of blocking PD - L1.

These differences can affect the biological identity of nanoparticles and thus alter their interaction with the cells.

Interaction between the PD - 1 protein found on killer T cells and its binding partner PD - 1L is one hallmark of immune exhaustion, and interfering with this interaction a potential strategy to overcome it.

After moving to Berkeley, he arrived at a career crossroads in 1994, when Spyros Artavanis - Tsakonas, then at Yale, discovered and subsequently patented the human relative of the fruit fly gene notch, which plays a role in cell - to - cell interactions and could be an anti-cancer target.

This suggests that «the python intestine may represent a valuable model for studying the interactions of metabolism with the regulation of cell division / death and WNT signaling relevant to cancer,» the researchers said.

By means of targeted genetic modifications, the research team succeeded in steering the degree of entanglement between pili and hence the interaction forces between cells.

«We now have a handle on the detailed structure of a complex web of interactions that causes global dysfunction in cells resulting in degeneration of the brain.»

Dr. Del Maestro adds, «Yong and colleagues at the University of Calgary have begun to unravel the complex interaction of the microglia with the brain tumor cells, resulting not only in furthering our understanding, but providing a new concept and drug which can now be immediately assessed in clinical trials.»

So to see [that] this powerful action [occurred] as result of the interaction took [of just] a few cells was quite dramatic and I just loved it.

Researchers, led by Joshua Mayourian at the Icahn School of Medicine at Mount Sinai, used mathematical modeling to simulate electrical interactions between these stem cells and heart cells to develop insight into possible adverse effects, as well as to hypothesize new methods for reducing some potential risks of this therapy.

Identifying a role for tuft cells in the interactions between the virus and its host «is a significant step forward,» says immunologist David Artis of Weill Cornell Medicine in New York City, who was not involved in the study.

Metastatic melanoma is the deadliest of the skin cancers and the mechanisms that govern early metastatic growth and interactions of metastatic cells with the brain microenvironment remain shrouded in mystery.

They then used fluorescent antibodies that bind specifically to the protein to trace the virus's interactions with various kinds of cultured cells.

When they administered minocycline — a tetracycline antibiotic with anti-inflammatory properties commonly used to treat bacterial infections, acne and arthritis — many of the abnormalities in the astroglial cells were corrected and there were more healthy interactions between the astroglia and neurons compared to the control cells without the defect.

Development of new therapies for the prevention and treatment of prostate cancer bone metastasis depends on understanding the dynamic reciprocal interactions between prostate cancer cells and the bone microenvironment.

Weeraratna's team used an artificial skin reconstruct model to recreate the interactions of melanoma cells with either a young or aged tumor microenvironment.

DMNT inhibitors, such as 5 - azacytidine and decitabine, boost the interactions of PARP inhibitors to block these proteins even further, causing cancer cell death, the researchers found.

Earlier, for his Ph.D., he used his physics training to study biological interactions at the molecular resolution — but for his postdoc he changed approaches dramatically, turning to cell biology and applying his skills to the development of high - resolution functional imaging of DNA transcription in living cells.

Using fluorescence inside living cells as well as biochemistry, they showed that SMN promotes an interaction between the «zipcode» region of a test RNA and a transport protein.

Previous work from Dekker and colleagues had shown that points of interaction along the chromosome influence gene expression and are the reason why different cell types are organized differently in three dimensions.

Since many human diseases can be explained by perturbations of molecular interactions within cells, interactomes will drastically change how we think about human health, and how we set about designing drugs and preventive measures to counter illness.

Although biologists have known for decades that egg cells provide sperm with a little chemical encouragement to reel them in, the molecular nature of this interaction has remained elusive.

Image courtesy of iStockphoto / BakiBG SAN ANTONIO, Texas — So much of our information from — and interaction with — the world is now mediated by computers, cell phones and tablets that health experts have been practically running themselves ragged trying to find ways to use these conduits to help people make healthier choices.Great success stories have come out of parts of the developing world, where cell phones have been used to improve maternal and infant care and help people adhere to medication guidelines.

Most of Dodgeball's interactions rely on the basic text - messaging features built into modern cell phones.

Cyclin D is synthesized during the first stage of cell replication and is believed to help drive the complex, multi-stage process, including interaction with the retinoblastoma (Rb) protein, whose function is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide.

Biologists, physicists, mathematicians, and computer scientists have begun cooperating on a sophisticated «systems biology» aimed at understanding how the countless molecular interactions at the heart of life fit together in the workings of cells, organs, and whole animals.

By investigating the interactions within algal colonies, researchers hope to understand how single cells took the evolutionary leap to mass organization hundreds of millions of years ago.

In the absence of mutation, the interactions between cells may look like competition, but one trait is not replacing another and hence he misses a critical distinction by putting them in the same pigeonhole.

The teams are currently working on the fabrication of 3D structures from the blend suitable for implantation in patient joints with future studies focusing on understanding the peculiar interactions between the blend and stem cells towards refining the quality of regenerated cartilage.

Now, a team of scientists at the Icahn School of Medicine at Mount Sinai have developed the Just EGFP Death - Inducing T - cell, or JEDI T - cells, which enable the visualization of T - cell antigens, allowing researchers to study T - cell interactions with different cell types, model disease states, and finally determine the functions of otherwise poorly characterized cell populations.

Under the supervision of Claudia Binder, MD / PhD, I also carry out research, examining the interactions of tumour cells and macrophages.

Using an advanced imaging technique called intravital microscopy, the researchers followed the movement and interaction of HIV - infected cells in the spleen of mice.

In a 2006 study published in Cell, Vidal and Huda Zoghbi, a neurobiologist at Baylor College of Medicine in Houston, Texas, teamed up to show previously unsuspected interactions among the proteins produced by mutated genes in several of the movement disorders known as ataxias.