Sentences with phrase «of cell migration»

The findings of the project also reveal how the same mechanisms of cell migration remain intact in the course of evolution, making it possible to draw comparisons between fish and humans.

It actively engages biologists working on distinct molecular mechanisms of cells migration and helps them interact beyond the boundaries of independent laboratories.

A study by Sofia J. Araújo, a Ramón y Cajal researcher with the Morphogenesis in Drosophila lab at the Institute for Research in Biomedicine (IRB), elucidates the genetic regulation of cell migration.

A team of researchers at the Massachusetts General Hospital and Harvard Medical School in Boston has developed technologies for precision measurement of cell migration speed before and applied the new tool to study the variations of migration speed in population of cancer cells.

Researchers from the Department of Biomedicine at the University of Basel discovered novel mechanisms of cell migration by observing cells moving on lines of connective tissue.

Microfluidic tools for precision measurements of cell migration speed reveal that migratory speed of individual cells changes stochastically from parent cells to their descendants, while the average speed of the cell population remains constant through successive generations.

Failure to degrade RAPGEF2 in epithelial cells results in sustained activity of Rap1 and inhibition of cell migration induced by HGF, a potent metastatic factor.

Why It Matters: This knowledge could lead to a better understanding of cell migration in cancer metastasis and inflammatory disease, which in turn will help in the development of effective treatment methods.

The team from the Massachusetts General Hospital plans to use the microfluidic devices in synergy with some more sophisticated molecular biology tools and identify the control factors of cell migration speed.

«New regulatory mechanisms of cell migration found in drosphilia fly study.»

The scientists describe novel concepts of cell migration, which could help to find new targets and approaches to fight cancer metastasis and inflammation.

Arrow indicates the direction of cell migration.

This type of cell migration is called chemotaxis, and it happens in both healthy and diseased cells.

Our insight will substantially enhance our understanding of dynamic cell shape regulation for instance in the context of cell migration as in cancer metastasis or during morphogenesis.

Induction of cell migration by matrix metalloprotease - 2 cleavage of laminin - 5.

Here we discuss the possible switch mechanism for the two modes of actin organisation and the advantages of each in the perspective of cell migration and invasion during tumour metastasis.

This direct link between Exocyst and WRC complexes provides a novel mechanistic insight into the spatio - temporal regulation of cell migration.

Inhibition of cell migration and invasion of enzalutamide - resistant prostate cancer cells was effected by niclosamide through its effects on the androgen receptor (AR)- STAT3 signaling axis [40].

These results are relevant to our understanding of cell migration and metastasis.

«The more insights we get into the mechanisms of cell migration, the more effectively and focused we will be able to intervene in certain pathological processes,» first author Dr. Katrin Martin comments.

The broad objective of our research is to understand how epithelial cells interact with their microenvironment during migration, focusing on the mechanism of cell migration and the role of actin cytoskeleton in this process.