Sentences with phrase «of cells changes»

LifeTime proposes to go far beyond providing static tissue maps and to track, understand and predict how the molecular make - up of cells changes during human diseases and ultimately intervene.

A rush of ions into or out of cells changes the voltage inside.

Instead, the characteristic migration speed of each cell changes randomly through successive generations.

The new method, published today in the journal Nature Biotechnology, has implications for better understanding how different groups of cells change during disease progression, in response to drug treatment, or across evolution.

Free radicals are the natural by - products of cell change; smoke, radiation and other environmental factors can trigger cell change and the resulting free radicals, too.

Between the two periods separated by 75 years, 8 % of the cells changed climate type.

Not exact matches

The wrong set of changes to a single cell's genetic code, combined with other system breakdowns, can lead to cancer.

Nevertheless, this research is monumental because a better understanding of how our cells behave could eventually allow for such world - changing breakthroughs such as personalized medicine.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Also, they have chosen a cheap populist theme, attacking cell phone, bank and credit - card charges instead of hammering the Conservatives on their dangerous, right - wing deregulation agenda — even though people are still dying as a result of Harper's «self - regulation» changes to food safety.

In an earnings call later that summer, Peter Rive, who was then SolarCity's CTO, explained the merits of the changes to shareholders: «We don't want to rush to actually initiate some of the equipment installation for the cell line and then have that be a regretful layout only months later.»

This provides a game changing advantage in regenerative medicine that otherwise relied on the concept of stem cells.

As a cancer researcher, do you think the mechanisms of tumor growth are somehow changing to come into line with your perceptions, or is it possible that the process of our learning more about DNA mutations and cell architecture and nutrient exchange and epigenetic effects make it possible for us to inch ever closer to understanding that which is already going on under our noses?

Whether it is changing text books to teach religion as a «science,» making laws that prohibit stem - cell research which would without question help those in need, to stopping of any kind of gay rights, trying to put religion (christianity) into schools, a woman's right to choose, etc, etc...

Many of these mutants are likely non-viable; however, many will have subtle changes to their functional components, including the HA gene which allows the virus to bind host cells, and NA gene which allows the virus to escape from host cells.

The evolutionary, ecological perspective insists that we are, in the most profound way, «not our own»: we belong, from the cells of our bodies to the finest creations of our minds, to the intricate, ever - changing cosmos.

That balance has changed considerably in the past few years, as alternative avenues of stem - cell science have opened up and it increasingly seems like whatever therapeutic potential such cells may someday have could be explored and achieved without the destruction of embryos.

Thus, the transition from instinct to reason results in the radical transformation of the animal into man; matter as it evolves toward the cell becomes radically transformed into living matter; and vegetative life becomes qualitatively changed into conscious life.

At Key Stage 3 (age 11 to 13 +, Years 7 to 9) schools have to teach: that fertilisation in humans and flowering plants is the fusion of a male and a female cell; about the physical and emotional changes that take place during adolescence; about the human reproductive system, including the menstrual cycle and fertilization; how the foetus develops in the uterus, including the role of the placenta.

... yeah suzy and others... I just happen to realize that when monkey devolving didn't quite work out on paper it all changed to single cells and from the slime off of the worlds garbage can and so on... I just happen to know more than you think... In another ten or twenty years the science books will all have a new teaching... the Bible has been around and hasn't changed one word in over two thousnad years..

A clump of cells with no brain, and no neural tube is no more «a human life» than cells from your skin layer, or a sperm cell with no change of fertilizing an egg.

What model exists to explain what would have been the greatest quantum change in the history of the universe, namely the first cell?

The cell theory of organisms was a change in principle, not merely in degree, compared to all ancient thought.

The stem - cell breakthroughs haven't changed any of this» they illustrate it.

(Cf. the phenomenon of the «runners» at first connected with the mother plant and then separated from it; the fluid transition between various plants and animals which appear to be one; the germ - cell inside and outside the parent organism, etc.) Living forms which present what are apparently very great differences in space and time can ontologically have the same morphological principle, so that enormous differences of external form can derive from the material substratum and chance patterns of circumstance without change of substantial form (caterpillar - chrysalis butterfly).

Change is due to chance; the replication of multiplying cells is not exact, with consequent mutations occurring.

In the June 2010 issue of Nature Medicine, in an interview with theBoston - based researcher, Daley tells how he further changed the focus of his work after Prof. Shinya Yamanaka of Kyoto University, who won the 2010 Kyoto Prize for advanced technology, made known his successes with iPS cells in 2007: «Once Yamanaka solved the problem, I turned around virtually my entire programme to take advantage of that breakthrough,» he says.

Also there is evidence of molecular mechanisms in the cell membranes that can amplify small changes in the field to produce large changes in neural activity.13 On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect on behavioral measures (see note 11 for reference to these studies).

Such was the comfortable vista which, less than a century ago, began abruptly to change beneath our gaze, something in the fashion of those organic tissues in the living body which, after long remaining harmless and dormant, their cells apparently indistinguishable from those of the surrounding tissue, suddenly burst into dangerous growth.

We belong, from the cells of our bodies to the finest creations of our minds, to the intricate, ever changing cosmos.

In a similar vein Mr. Percival Lowell writes: «When we have, as we say, an idea, what happens inside of us is probably something like this: the neural current of molecular change passes up the nerves, and through the ganglia reaches at last the cortical cells....

Under Child's theory there is complete continuity from the reaction of the cell with its environment, which constitutes the primary metabolic gradient, and from the later reactions, by which the pattern of the developing embryo is laid down in accordance with the changing gradient pattern, to the intellectual processes by which the adult organism adjusts its relations to the outside world.

The DNA blueprints for each cell is written in a common chemical language capable of adapting to changing environmental conditions.

Since all living things are made of cells, evolution merely describes how cells change over time.

OK, here we go: Get a new hobby, be physically fit, get plenty of rest, go on a personal retreat, start mountain biking, don't turn on your computer or cell phone for one day a week, go to a creative leader conference and read the book 51 Ways for Revolutionary, Creative, Cutting - Edge, Innovative, Futuristic, Trailblazing, Missional, Catalytic, Groundbreaking, World - Changing Leaders to Stay Inspired.

The recent news that the promise of stem cell research can be pursued without using human embryos has permanently and dramatically changed the stem cell debate.

Instone - Brewer's own narrowing of the question of individual life -LRB-»... when does an embryo change from being a bundle of undifferentiated cells into a living human individual?»)

To alter a person's germ cells is to make a change that may be passed on through generations of descendants.

Some of the changes include automated electronic sensors to ensure cell checks, an on - duty nurse or EMT at all times and additional funds for jail intaking, inmate screening and training for police there.

And let's remember that evolution, while it's a theory, is a theory about the beginning and the transformation of life based on things we have observed, namely that cells change and mutate and that those mutations can produce cells that are unique and new, and that it would follow that it's possible for molecules to form into single - celled organisms which mutate and combine into multi-cellular organisms which mutate, adapt, and grow over time into new forms of life.

Ecological perspective insists that we are in the most profound ways, «not our own» we belong from the cells of our bodies to the finest creation of our minds, to the intricate, constantly changing cosmos.

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Extracts from this garlic even protected cells in a laboratory dish from certain types of damage.13 This isn't really surprising when you consider the nutritional changes that typically occur in plants when they sprout.

Seriously, when you start getting down to a microscopic level and looking at atoms and molecules and the structures of cells, the world changes.

Food Allergy Center research investigator and lead author of the study Jessica O'Konek said: «We're changing the way the immune cells respond upon exposure to allergens.

Such methods include cell fusion, microencapsulation and macroencapsulation, and recombinant DNA technology (including gene deletion, gene doubling, introducing a foreign gene, and changing the positions of genes when achieved by recombinant DNA technology).»

The change in length along the Primary Axis of the load cell between no - load and Rated Load conditions.

The change in load cell output occurring with time, while under load, and with all environmental conditions and other variables remaining constant; usually measured with Rated Load applied and expressed as a percent of Rated Output over a specific period of time.

We ran out of diapers on day 6 of 8, no problem — contacted the family concierge via the cell phone provided and she came and got a $ 20 note, sent a bellman to the stores off the resort and brought both the bought diapers, receipt and change back to me at the pool ---- huge tip provided to her and the bell boy, but worth it!

During intense or extensive exertion, the sickle hemoglobin can change the shape of red blood cells from round to quarter - moon, or «sickle.»