Sentences with phrase «of cells in a dish»

A cell in my brain is different from a cell not in my brain but, say, in a culture of cells in a dish.

«They are a bunch of cells in a dish, like a soup,» he says.

With our new technology, we can quickly create billions of these cells in a dish and then transplant them into damaged hearts to treat heart failure.»

Not exact matches

Growing cells in Petri dishes sounds like the stuff of science fiction, but the basic elements of the science are actually decades old.

When undifferentiated cells are put in a dish of nutrients that enables them to grow and divide, they fail to differentiate as they would in the embryo.

Extracts from this garlic even protected cells in a laboratory dish from certain types of damage.13 This isn't really surprising when you consider the nutritional changes that typically occur in plants when they sprout.

People who include dishes like carrot soup in their diets on a regular basis also enjoy reduced cholesterol levels, healthy teeth, and gums, wrinkle prevention, the slowing down of aging of the cells in your body, as well as a clean colon.

Now one team reports in ACS» journal Environmental Science & Technology that small amounts of house dust containing many of these compounds can spur fat cells to accumulate more triglycerides, or fat, in a lab dish.

Chemical biology and drug discovery usually depend on screens of cells in lab dishes, for example.

To develop their «disease in a dish» model, the team took skin cells from patients with Allan - Herndon - Dudley syndrome and reprogrammed them into induced pluripotent stem cells, which then can be developed into any type of tissue in the body.

The cells or organisms could be in a plate or dish, or in the head of a mouse; it doesn't matter.

First, the effects they saw have so far only been replicated in cells growing in a laboratory dish, using high concentrations of AA147.

WASHINGTON — Tiny orbs of brain cells swirling in lab dishes may offer scientists a better way to study the complexities of the human brain.

«These predictive algorithms seem to do a good job when CRISPR is performed in cells or tissues in a dish, but whole genome sequencing has not been employed to look for all off - target effects in living animals,» says co-author Alexander Bassuk, MD, PhD, professor of pediatrics at the University of Iowa.

The cells rose from the bottom of the dish in response to the magnet and clumped together at the interface between the gel and the air.

In lab dish experiments, exo - AAV successfully penetrated 50 - 60 percent of hair cells, the researchers observed.

Scientists we sent Anand's poster presentation to said that although the team has indeed grown some kind of miniature collection of cells, or «organoid», in a dish, the structure isn't much like a fetal brain.

After deciphering this natural differentiation process, the investigators duplicated it in the laboratory dish by adding a sequence of proteins, called growth factors, to the fluid bathing the stem cells.

A swab of a patient's bladder cells were cultured in a dish, molded to the shape of the bladder, and tacked onto their original damaged organ, restoring function.

Although proteasome inhibitors are very efficient in selective killing of cancer tumor cells grown in a dish (in - vitro), their success in the clinic has largely been undermined by the development of resistance — mechanisms of which are poorly understood.

The team found that exposing samples of human glioblastoma tumours grown in a dish to the Zika virus destroyed the cancer stem cells.

As those cells proliferated in laboratory dishes, the bits of human DNA were also copied, creating cell lines, each of which had a different fragment.

After 381 days, this cow's antibodies prevented 96 percent of the 117 HIV types from infecting cells in a lab dish.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

That would be getting close to the number of cells in a mouse brain,» raising the distant prospect of a human brain organoid with cognitive and even emotional capacities, all while sitting in a lab dish.

In addition to looking at mouse models of diabetes, the researchers also showed that exposure of human pancreatic islet cells — both from healthy donors and from patients with Type 1 diabetes — to fasting - mimicking diet in a dish stimulated insulin productioIn addition to looking at mouse models of diabetes, the researchers also showed that exposure of human pancreatic islet cells — both from healthy donors and from patients with Type 1 diabetes — to fasting - mimicking diet in a dish stimulated insulin productioin a dish stimulated insulin production.

Avivi's team has found out that fibroblast skin cells from the armpits of the rats can kill human cancer cells in a dish.

That allowed tumor cells to survive gemcitabine treatment in lab dishes and mouse studies, Leore Geller of the Weizmann Institute of Science in Rehovot, Israel, and colleagues discovered.

But there are many hurdles: Among them, growing enough of the cells in a petri dish and ensuring that they connect to «the existing machinery» in the eye, says Hendrik Scholl, who co-directs the Center for Stem Cells and Ophthalmic Regenerative Medicine at Johns Hopkins University in Baltimore, Marycells in a petri dish and ensuring that they connect to «the existing machinery» in the eye, says Hendrik Scholl, who co-directs the Center for Stem Cells and Ophthalmic Regenerative Medicine at Johns Hopkins University in Baltimore, MaryCells and Ophthalmic Regenerative Medicine at Johns Hopkins University in Baltimore, Maryland.

Matteo Boretto, the first author on this study, commented that «we were very excited to see that we could not only robustly grow and amplify endometrial tissue in a dish, but that the tiny structures were also able to reproduce normal responses of the endometrium to hormones: oestrogen makes the tissue thicken, progesterone then induces maturation including folding (see picture), and subsequent removal of both hormones mimics the cell shedding of the menstrual period.»

«We know that if you take these tumor cells out of a patient and put them in a petri dish, they can be killed by chemotherapy,» Beatty said.

To find out, they put droplets of culture medium that cancer cells had grown in on one side of petri dishes.

Next, the research team will examine specifically whether these liver cells obtained from human embryonic stem cells in a dish help repair injured livers in preclinical animal models of liver disease.

They used mice and cartilage cells in a dish to study one mutant form of IDH that is identified only in cartilage cells.

They also suggest it may soon be possible to mature the cells in a laboratory dish simply by adding a cocktail of microRNAs to the cell culture.

Zheng, together with Leah Boyer, then a researcher in Gage's lab and now director of Salk's Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a dish.

Mouse brain nerve cells (green) making a disease - causing version of the tau protein were grown in lab dishes with supporting brain cells called glia.

CELLS GONE WILD Turning off the gene Apc in mouse intestinal cells in a culture dish spurs out - of - control cell growth (left panel, pCELLS GONE WILD Turning off the gene Apc in mouse intestinal cells in a culture dish spurs out - of - control cell growth (left panel, pcells in a culture dish spurs out - of - control cell growth (left panel, pink).

Because the sperm cells used in IVF often need all the help they can get, switching to the diamond petri dishes could give them just the boost they need to fulfill their destiny — thus potentially ramping up the notoriously low success rate of IVF.

«To date, there has been no systematic means of assessing the fidelity of cellular engineering — to determine how closely cells made in a petri dish approximate natural tissues in the body,» says George Q. Daley, MD, PhD, Director of the Stem Cell Transplantation Program at Boston Children's and senior investigator on both studies.

Xu and colleagues grew S. gallolyticus in lab dishes with several different types of human cells.

The new «tumor in a dish» method begins by taking the cancerous tissue removed during surgery or biopsy, cutting it up into small pieces and putting them in a special collagen gel that maintains them as «organoids» that retain the three - dimensional structure of the original tumor and include supporting cells from the tumor's environment.

Glioblastomas in lab dishes and mouse brains are fakes, little Potemkin villages that everyone thought were faithful replicas of human glioblastomas but which, lacking tumor stem cells, were nothing of the kind.

To test whether the new spheroids were a better mimic for functional dermal papilla cells than those that had been grown in typical dishes, Christiano and her team determined what genes were turned on and off in different sets of dermal papilla cells.

According to his unpublished findings, when he puts glioblastoma cells from patients into lab dishes with brain organoids, the cells attach to the surface of the organoids, burrow into them, and within 24 to 48 hours grow into a mass that eventually «looks exactly like what happened in the patient's own brain,» Fine said.

But when dermal papilla cells from humans are put into dishes in the lab, they lose their ability to induce the formation of new follicles.

They then put the dishes into special chambers called bioreactors that keep them warm and in gentle motion reminiscent of a womb, encouraging the cells to form blobs with working neurons and many other features of a full - size human brain.

In cells grown on flat culture dishes, the expression of thousands of genes didn't match up with their normal patterns, explaining why the cells from those dishes had been unable to generate new hair follicles.

Rather than stick the isolated cells on a flat culture dish, they mixed the cells with liquid, then let the mixture hang in tiny droplets from a plastic lid, like condensation on the roof of a container.

«Alzheimer's in a dish: Stem cells from patients offer model and drug - discovery platform for early onset form of disease.»