Using a miniature microscope inserted into the brains of the mice, Hen's team recorded the activity of hundreds
of cells in the hippocampus as the mice freely moved around their surroundings.
«We were able to demonstrate for the first time that these specific cells — a small group
of cells in the hippocampus — had undergone this augmentation of synaptic strength,» Tonegawa says.
O'KEEFE: I'd have to say there was quite a bit of skepticism on several grounds when we first started reporting that we could show very specific correlates to the activity
of cells in the hippocampus, and specifically, that they were related to where the animal was in the environment.
Using a miniature microscope inserted into the brains of the mice, the researchers recorded the activity of hundreds
of cells in the hippocampus as the mice freely moved around their surroundings.
Chronic stress, and the depression that often follows it, have been found to decrease the functioning and number
of cells in the hippocampus, an area of the limbic system, the emotional brain, involved in memory.
Not exact matches
Specifically, it appears that exercise stimulates neurons (nerve
cells) to grow
in the
hippocampus, the part
of the brain responsible for memory.
«
In animal studies, exercise has been shown to specifically affect the hippocampus, significantly increasing the growth of new neurons and cell survival, enhancing memory and learning, and increasing molecules that are involved in the plasticity of the brain,» Chaddock sai
In animal studies, exercise has been shown to specifically affect the
hippocampus, significantly increasing the growth
of new neurons and
cell survival, enhancing memory and learning, and increasing molecules that are involved
in the plasticity of the brain,» Chaddock sai
in the plasticity
of the brain,» Chaddock said.
Neural stem
cells with the ability to form new neurons
in the brain are normally present
in the
hippocampus (the part
of the brain connected to learning and memory) and
in the subventricular zone
of the brain.
In 2011 researchers found that these waves of electricity cause neurons in the hippocampus, the main brain area involved with memory, to fire backward during sleep, sending an electrical signal from their axons to their own dendrites rather than to other cell
In 2011 researchers found that these waves
of electricity cause neurons
in the hippocampus, the main brain area involved with memory, to fire backward during sleep, sending an electrical signal from their axons to their own dendrites rather than to other cell
in the
hippocampus, the main brain area involved with memory, to fire backward during sleep, sending an electrical signal from their axons to their own dendrites rather than to other
cells.
Boldrini surmised that reduced cognitive - emotional resilience
in old age may be caused by this smaller pool
of neural stem
cells, the decline
in vascularization, and reduced
cell - to -
cell connectivity within the
hippocampus.
Biologist Ann Cornell - Bell
of Viatech Imaging
in Ivoryton, Connecticut, put on display star - shaped
cells, called astrocytes, from the rat
hippocampus, a brain region associated with long - term memory.
They discovered that the chemicals and radiation used to kill tumor
cells damage the stem
cell reservoir
in the
hippocampus and nearly halt the formation
of new neurons
in both children and adults.
Specifically, they drew RNA from the
hippocampus, which is the part
of the brain that helps regulate learning and memory, and from leukocytes, white blood
cells that play a key role
in the immune system.
Samuel Weiss, director
of the Hotchkiss Brain Institute at the University
of Calgary, and his colleagues reported that nerve
cells sprouted
in the olfactory bulb, the seat
of the sense
of smell, and
in the
hippocampus, the brain's memory bank.
The sex - specific differences — the smaller
hippocampus, the presence
of fewer nerve
cells, the existence
of immune system macrophages
in places they shouldn't be — were also found
in adulthood.
In the brains of the diseased mice, however, nearly all the cells congregated in the hippocamp
In the brains
of the diseased mice, however, nearly all the
cells congregated
in the hippocamp
in the
hippocampi.
NEW ROLE A kind
of brain
cell called an astrocyte (shown) may help nerve
cells in the
hippocampus form traumatic memories, a study
in rats suggests.
In contrast to earlier prominent studies, Shawn Sorrells of the University of California, San Francisco and his colleagues failed to find newborn nerve cells in the memory - related hippocampi of adult brain
In contrast to earlier prominent studies, Shawn Sorrells
of the University
of California, San Francisco and his colleagues failed to find newborn nerve
cells in the memory - related hippocampi of adult brain
in the memory - related
hippocampi of adult brains.
There is nothing extraneous here
in this painting
of two pyramidal
cells, a type
of neuron found
in the cerebellum and
hippocampus.
DWINDLING DOWN Young nerve
cells (green) were spotted
in the memory - related
hippocampus of a newborn (left), but rarely
in a sample from a 13 - year - old (center).
In May researchers at McGill University reported that the gene responsible for creating cells» protein - building machinery is more frequently methylated in the hippocampus — the brain region responsible for short - term memory and spatial navigation — of depressed suicide victims who suffered child abuse than in the brains of nonsuicide victims who were not abuse
In May researchers at McGill University reported that the gene responsible for creating
cells» protein - building machinery is more frequently methylated
in the hippocampus — the brain region responsible for short - term memory and spatial navigation — of depressed suicide victims who suffered child abuse than in the brains of nonsuicide victims who were not abuse
in the
hippocampus — the brain region responsible for short - term memory and spatial navigation —
of depressed suicide victims who suffered child abuse than
in the brains of nonsuicide victims who were not abuse
in the brains
of nonsuicide victims who were not abused.
In a second study, (abstract 3.312) researchers from the Federal University of São Paulo show that reduced cell density in certain parts of the hippocampus may be linked to deficits in short - and long - term memory in certain patients with TLE - H
In a second study, (abstract 3.312) researchers from the Federal University
of São Paulo show that reduced
cell density
in certain parts of the hippocampus may be linked to deficits in short - and long - term memory in certain patients with TLE - H
in certain parts
of the
hippocampus may be linked to deficits
in short - and long - term memory in certain patients with TLE - H
in short - and long - term memory
in certain patients with TLE - H
in certain patients with TLE - HS.
While the regenerative capability
of brain
cells,
in the
hippocampus — the part
of the brain responsible for learning and memory — slows down as part
of the aging process, the Rutgers scientists determined that the process that occurred after a head injury was related to injury and not age.
«
In the past it was deemed technically impossible to follow single cell stem cells in the brain over time given the deep localization of the hippocampus in the brain,» said Jessberge
In the past it was deemed technically impossible to follow single
cell stem
cells in the brain over time given the deep localization of the hippocampus in the brain,» said Jessberge
in the brain over time given the deep localization
of the
hippocampus in the brain,» said Jessberge
in the brain,» said Jessberger.
In a new study published in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampu
In a new study published
in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampu
in Science, the laboratory
of Sebastian Jessberger, professor
in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampu
in the Brain Research Institute
of the University
of Zurich, has shown for the first time the process by which neural stem
cells divide and newborn neurons integrate
in the adult mouse hippocampu
in the adult mouse
hippocampus.
In a famous set of experiments in human subjects in 2005, neuroscientist Rodrigo Quian Quiroga found that pictures of actor Jennifer Aniston activated a single brain cell in the hippocampus region — the so - called Jennifer Aniston neuro
In a famous set
of experiments
in human subjects in 2005, neuroscientist Rodrigo Quian Quiroga found that pictures of actor Jennifer Aniston activated a single brain cell in the hippocampus region — the so - called Jennifer Aniston neuro
in human subjects
in 2005, neuroscientist Rodrigo Quian Quiroga found that pictures of actor Jennifer Aniston activated a single brain cell in the hippocampus region — the so - called Jennifer Aniston neuro
in 2005, neuroscientist Rodrigo Quian Quiroga found that pictures
of actor Jennifer Aniston activated a single brain
cell in the hippocampus region — the so - called Jennifer Aniston neuro
in the
hippocampus region — the so - called Jennifer Aniston neuron.
Previous studies have shown that the ability
of adult mice to grow new nerve
cells in the
hippocampus can be influenced by genetic background, Gage says, suggesting that this ability may vary widely across species.
Moser demonstrated a number
of changes
in the strength
of connections between nerve
cells — a phenomenon called synaptic plasticity —
in the
hippocampus as rats stored information
in their long - term memory.
The scientists zeroed
in on the
cells from the
hippocampi of the cadavers, examining the switch for the stress hormone gene they had studied
in rats.
In the
hippocampus, activity patterns
of nerve
cells associated with a particular experience, such as running a maze, reoccur but at a faster pace on replay.
To answer this question
of nature versus nurture, the researchers took
cells that would grow to become chandelier
cells in the
hippocampus and transplanted them into the neocortex, and took
cells that would grow to become neocortical chandelier
cells and transplanted them to the
hippocampus.
«Because the structure we detected was similar
in all three experimental conditions, we think that we are picking up the fundamental organization
of place
cells in the
hippocampus,» said Itskov.
Scott and his colleagues can now identify «
cell sickness»
in the part
of the
hippocampus related to Alzheimer's disease.
In the lab, they adapted the standard experimental technique for studying place cells: implanting electrodes directly into a rat's hippocampus and recording from them as the animal runs freely in a large box (see «A sense of place»
In the lab, they adapted the standard experimental technique for studying place
cells: implanting electrodes directly into a rat's
hippocampus and recording from them as the animal runs freely
in a large box (see «A sense of place»
in a large box (see «A sense
of place»).
Andersen was studying the activity
of neurons
in the
hippocampus — a brain area associated with memory — and the two students wanted to try to link this precise activity
of cells with the behaviour
of animals.
Neuroscientists Jing Wang and Freda Miller, both then at Toronto's Hospital for Sick Children, showed that when nondiabetic mice are given metformin, their memory improves, thanks to an increase
in the neural stem
cell population and
in the number
of these
cells that develop into healthy neurons
in the
hippocampus, the brain's memory center.
By measuring the amount and location
of the
hippocampus cell firing, the researchers were able to determine that the neurons fired
in the exact reverse order
of the firing that occurred when the rat scurried from one end
of the track to the other.
Given that lot
of those brain
cells seemed to form down
in the area
of the
hippocampus, which is involved with the memory and with learning, it was an easy jump to naturally assume that they must be involved with that
in some way.
The chemical labels newly divided
cells, and
in their brain tissue, it showed up
in a sprinkling
of neurons
in the
hippocampus — a seahorse - shaped structure involved
in memory and learning.
From the
cells» ages, the group calculated that every day, humans replace 700
of their neurons
in the dentate gyrus, a sliver
of hippocampus thought to encode memories.
«Many neurons — including those
in the
hippocampus — showed a sudden burst
of activity shortly after eye movements
in sleep, typically observed when these
cells are «busy» processing new images.»
Michael Young and colleagues derived neural stem
cells from the
hippocampus of adult rats and then injected them into the gel - like vitrous
of eyes
in rats showing retinal degeneration.
For their analyses, the scientists specifically colored the places
of origin
of axons
of so - called pyramidal
cells in the
hippocampus.
The
cells were located
in a part
of the
hippocampus — a pair
of seahorse - shaped structures located deep within the brain and involved
in memory and learning.
Both the healthy mice and the mice without Narp had three times the number
of new
cells in the
hippocampus after ECT than the mice that were given the sham procedure.
By examining the
hippocampus — a portion
of the brain associated with the process
of learning — after the rats learned to associate a sound with a motor response, scientists found that the new brain
cells injected with dye a few weeks earlier were still alive
in those that had learned the task while the
cells in those who had failed did not survive.
To see if Narp played a role
in making these new
cells in mice, the researchers injected a synthetic molecule, BrdU, to label and allow detection
of newly created
cells that would become neurons
in the
hippocampus.
Chen and his team began by studying how reactive glial
cells respond to a specific protein, NeuroD1, which is known to be important
in the formation
of nerve
cells in the
hippocampus area
of adult brains.
«Now that we've found these
cells in the
hippocampus, it opens up new areas for exploring treatment ideas that we didn't know existed before,» says the study's lead author Jessica Jimenez, PhD, an MD / PhD student at Columbia University's Vagelos College
of Physicians & Surgeons.
It was already known that a few weeks after an ECT procedure or after taking an effective antidepressant that stem
cells in the
hippocampus turn on and make more copies
of hippocampal neurons.