Sentences with phrase «of cells in the lab»

Chemical biology and drug discovery usually depend on screens of cells in lab dishes, for example.

Scientists have made a key discovery that could speed up the production of cells in the lab for studying diseases such as multiple sclerosis and Parkinson's disease.

Sheer mass is a major issue — it's very difficult to nourish a 3 - D population of cells in the lab on the scale of a liver.

Not exact matches

«We suspected that the young are most vulnerable because of their immature immune systems, but we didn't have a lot of hard evidence to show that before,» said study lead author Bo Hang, a Berkeley Lab staff scientist who previously found that thirdhand smoke could lead to genetic mutations in human cells.

He earned degrees in cell biology and tissue engineering and eventually got a job in a lab run by Vladimir Mironov, who was investigating the use of bioprinting — 3 - D printing using living cells — to generate replacement organs.

A few days later, he told her about a lab in Columbus, Ohio, that was making fuel cells the size of pencil erasers.

This new kind of approach to fighting blood cancers is truly personalized; immune T - cells are extracted from patients, genetically tinkered to home in on an destroy cancerous cells, multiplied in a lab, and then jolted back into the patient's body within about two weeks.

Now in 2018, I don't want to project that everything was negative in 2017: we've seen such individuals as Nimrod May from Sirin Labs, individuals like Mikhail Mironov from ICORating, who are having one of the most successful ICOs of 2017, and now is coming out with one of the first cell phones that has an encrypted wallet included on an Android platform, which I think a phenomenal piece of technology moving forward.

So why is it that with all of our science and technology we are unable to create even the simplest cell in the lab under the perfect conditions?

While some still object to cells being taken from animals and used by scientists to grow clean meat in laboratories — and some just don't like the idea of eating a «cultured» steak created by men and women in white coats — others see the lab - grown meat revolution as key to solving the environmental crisis linked to meat eating.

In a lab study, an extract of the leaves stopped the growth and progression of prostate cancer cells by up to 75 % in micIn a lab study, an extract of the leaves stopped the growth and progression of prostate cancer cells by up to 75 % in micin mice.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellIn 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellin the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellin mice and in lab cultures, and it also prevented the growth of new tumor cellin lab cultures, and it also prevented the growth of new tumor cells.

02 Feb 2018 — Clean meat innovators Memphis Meats has been getting a lot of attention from investors recently with billionaire businessmen Richard Branson and Bill Gates staking their claim in the pioneering company last year — and now the venture capital arm of Tyson Foods has invested in the food tech startup which lab - grows meat directly from animal cells.

This may entail making small holes in the bone to allow new cartilage to grow (microfracture), taking cartilage from another part of the athlete's knee and transplanting it into the defect (osteochondral autograft transfer), taking cartilage cells from the knee and then having them grown in a lab for later re-implantation (autologous chondrocyte implantation), or taking cartilage from a person who has passed away and placing it in the defect (osteochondral allograft transfer).

This study built on previous research from the Sundrud lab, which showed that when TH17 cells entered the intestine in human tissue samples, they increased the expression of a gene called MDR1.

Mangahas «was a very important part of my lab,» Zakian says, and he was the first author on a paper published in the journal Molecular Biology of the Cell.

In an attempt to answer this question, the researchers undertook a targeted manipulation of leukemia cell DNA in the laIn an attempt to answer this question, the researchers undertook a targeted manipulation of leukemia cell DNA in the lain the lab.

Her interest was piqued: Upon graduating in 1999 she joined the lab of Ding Xue at the University of Colorado, Boulder, to study how cell death is regulated in the model organism Caenorhabditis elegans.

One of his professors, Dag Jenssen, persuaded Helleday to join his lab in the Department of Genetics, Microbiology, and Toxicology at Stockholm University to investigate the importance of recombination in somatic cells, tumor cells, and cancer initiation.

Now one team reports in ACS» journal Environmental Science & Technology that small amounts of house dust containing many of these compounds can spur fat cells to accumulate more triglycerides, or fat, in a lab dish.

But to coax them down a specific path in the lab requires recreating the precise sequence and timing of environmental cues in the womb — the signals from proteins and hormones that tell cells what kind of tissue to become.

But as the research in Yaniv's lab progressed, it became clear that scientists on both sides of the argument had been right: Lymphatic cells do indeed grow from veins, but they originate from a niche within the vein that harbors angioblasts.

In Robinson's lab, Sharon studied protein - protein interactions within proteasomes, large multiprotein complexes that clear cells of unwanted proteins by degrading them into small peptide fragments.

Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.

If true, this would be the first method to complete the final steps in making human sperm, although other labs have managed to push cells through some of the earlier stages.

«Our lab specializes in developing novel genetic methodologies to study T cell repertoires, but we had never applied this technology to study how the immune system responds to an infection,» says Emanual Maverakis, M.D., associate professor of dermatology at the University of California, Davis School of Medicine.

By studying human cancer cells and animal models of cancer in the lab, our researchers have shown that loss of PTEN leads to high levels of PI (3,4) P2, which could result in hyperactivation of AKT.

Sharon joined Anglister's lab for her master's project and Ph.D., studying the three - dimensional structure of a region in the HIV - 1 protein envelope that helps the virus enter human cells.

WASHINGTON — Tiny orbs of brain cells swirling in lab dishes may offer scientists a better way to study the complexities of the human brain.

Cells inside the brains contract, while cells on the outside grow and push outward, researchers at the Weizmann Institute of Science in Rehovot, Israel, discovered from working with the lab - grown brains, or organCells inside the brains contract, while cells on the outside grow and push outward, researchers at the Weizmann Institute of Science in Rehovot, Israel, discovered from working with the lab - grown brains, or organcells on the outside grow and push outward, researchers at the Weizmann Institute of Science in Rehovot, Israel, discovered from working with the lab - grown brains, or organoids.

In the lab, they studied plant xylem vessels — xylem cells make the tubes that transport water from the roots to the top of a tree.

Brainlike cell bundles grown in a lab may expose some of the biological differences of autistic brains.

«While there is much work to be done, these findings imply the possibility of taking a patient's Th17 cells, expanding them in the lab and then reinfusing them as a treatment,» adds Chen Dong, also of MD Anderson, who supervised the work.

They found high levels of the regulatory T - cells in patients treated with post-transplant cyclophosphamide, and lab - cultured cells survived cyclophosphamide treatment.

In lab dish experiments, exo - AAV successfully penetrated 50 - 60 percent of hair cells, the researchers observed.

In his second semester, he started doing research in three different labs, including that of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction of messenger RNIn his second semester, he started doing research in three different labs, including that of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction of messenger RNin three different labs, including that of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction of messenger RNA.

TWO types of human ear cell have been grown in the lab from fetal stem cells.

«Many diseases, especially complex diseases, involve multiple genes, and this system could be used therapeutically to target and activate multiple genes together and rescue these disease phenotypes,» says Albert Cheng, a graduate student in the Jaenisch lab and co-author of the Cell Research paper.

Bands on gels that form the Manhattan skyline, graphs that resemble comedy breasts, or smiley faces hidden in the nuclei of cells are the mainstay of every lab notice board, but they rarely make it to publication.

Previous work in Weinberg's lab had shown that after a tumor forms in one part of the body, some of the cancer cells undergo EMT, Mani explains.

Years ago W.U.'s Holtzman and former colleague Marc Diamond, who has since moved to the University of Texas Southwestern Medical Center, identified tau - binding antibodies that slow the spread of toxic tau clusters in a lab assay using cultured cells.

To investigate how the egg cell manages to rid itself of such a resilient structure, Joana Pinto, a PhD student in the Lénárt lab, developed fluorescent tags for mother and daughter centrioles in a starfish egg cell and recorded the entire process of eliminating them.

Mahmoudi and his colleagues previously identified several others overlooked biological factors that appear to contribute to discrepancies seen between results in the lab and in the clinic, including importance of personalized medicine at the nanobio interfaces, cell type, cell shape, and incubating temperature.

Still, only a few dozen labs in the world are certified as BSL4 facilities; some are very small and only work on diagnostics, or cell cultures, or a single species of animals.

In the lab, they also did an experiment to see if wash water from tunnels affected the protein activity in liver cells, or reduced the growth of an algae called Pseudokirchneriella subcapitatIn the lab, they also did an experiment to see if wash water from tunnels affected the protein activity in liver cells, or reduced the growth of an algae called Pseudokirchneriella subcapitatin liver cells, or reduced the growth of an algae called Pseudokirchneriella subcapitata.

The scientists also showed, in lab - cultured human cells, that an ALDH - blocking drug strips regulatory T - cells of their ability to grow and protect themselves from cyclophosphamide.

Horne and his colleagues controlled a Nokia 6310e cell phone — another popular and basic phone — attached to the head of 10 healthy but sleep - deprived men in their sleep research lab.

Each of the four compounds was then tested in the lab to see how it would affect a line of prostate cancer cells relatively sensitive to the chemotherapeutic Paclitaxel, commonly used to treat prostate cancer patients.

The cell was created by stitching together the genome of a goat pathogen called Mycoplasma mycoides from smaller stretches of DNA synthesised in the lab, and inserting the genome into the empty cytoplasm of a related bacterium.

At the same time, researchers have found that much smaller protein clusters called oligomers — made of only a few copies of these proteins — can be highly toxic to motor neuron - like cells grown in the lab and thus are more likely to be the chief causes of brain - cell death in these diseases.