Not exact matches
Knowledge
of the
cellular and molecular details
of these
adaptations could lead to new treatments for the compulsive behaviors that underlie addiction
This extreme morphology raises many
cellular challenges: in particular, the delay required to transport organelles and cargo from the soma to distant parts
of the axon can reach several hours and is incompatible with the rapid
adaptation of subcellular homeostasis.
Current efforts focus on elucidating the role
of molecular chaperones compartmentalized in mitochondria in regulating tumor bioenergetics,
adaptation to
cellular stress and cell survival.
Manuscripts typical
of this section would describe experiments generating and analyzing lists
of genes and studies
of how those genes combine to regulate: differentiation
of a particular cell type;
cellular, tissue, or organ response to toxic / pathogenic agents;
adaptation to environmental stresses.
Important features
of XMRV biology include (1) tropism for a variety
of cell lines, including prostate cancer DU145 and LNCaP cells [27], [43], [48], and human neural cell types [57], (2)
adaptations that promote growth in prostate epithelium and human - derived prostate cancer cell lines including an androgen response element in the promoter region [58] and downregulation
of APOBEC3G [59], and (3)
cellular effects with potential oncogenic properties including increased tumor aggressiveness mediated by downregulation
of p27 [60] and differential regulation
of several microRNAs [61].
Our model should allow studies
of the impact
of aneuploidy on molecular
adaptations and
cellular fitness.IMPORTANCE Aneuploidy is usually detrimental in multicellular organisms, but in several microorganisms, it can be tolerated and even beneficial.
Filament formation by metabolic enzymes is a specific
adaptation to an advanced state
of cellular starvation.
Are there any respectable studies that show, on a
cellular level, that slow fiber is slow, and nothing else, that fast fiber is fast and nothing else, or could these be just particular
adaptations that single fibers are capable
of in response to the tasks put before them?
In yet one more entry
of a shocking sequence bulletins that Nintendo has made tonight, the corporate simply revealed
cellular adaptation of Mario Kart can be hitting someday early subsequent yr.