Sentences with phrase «of cellular biochemistry»

This is too fundamental a part of cellular biochemistry for the rapid mutational evolution of cancer cells to work around, as they can for many of the standard approaches to cancer treatment at the present time.

As an approach that is much, much faster - and thus more cost - effective - than trying to infer the answer by analyzing the enormously complex workings of cellular biochemistry.

Not exact matches

Geneticists passed from the formal genetics of individuals to cytogenetics at the cellular level, to the biochemistry of DNA in duplication and in protein synthesis at the molecular level, back to physiological and developmental genetics again at the cellular level and back to the level of the individual in behavioral genetics and beyond the individual to population genetics and the theory of evolution.

Just as quantum mechanics is needed to, and does perfectly, fill the gap between the atomic structure of crystals and their beautiful shape in space, so too it will be needed to link the biochemistry of genetic code and cellular processes to the growth and shape of living things — provided, that is, that such a link can be found at all.

The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.

Allan Jacobson, Ph.D., of the University of Massachusetts Medical School and co-founder of PTC Therapeutics, the company that developed ataluren, and David Bedwell, Ph.D., professor of the UAB Department of Biochemistry and Molecular Genetics, have sought to understand precisely how ataluren allows the ribosome, the machinery of cellular protein synthesis, to skip over these inserted stop signs and produce proteins that have normal or near - normal function.

«We've long known that NF - kB promotes cancer development by subverting apoptosis, an internal safety mechanism that otherwise would cause cancer cells to self - destruct,» says principal investigator Denis Guttridge, PhD, professor of molecular virology, immunology and medical genetics and of molecular and cellular biochemistry.

«By the 30th day of culture, there were obvious clumps of fluorescent cells visible under the microscope,» says lead author Valentin Sluch, Ph.D., a former Johns Hopkins biochemistry, cellular and molecular biology student and now a postdoctoral scholar working at Novartis, a pharmaceutical company.

In order to be able to treat neurodegenerative disorders in future, researcher Ulrich Hartl, Head of the Department of Cellular Biochemistry at the Max Planck Institute of Biochemistry, and his team have for many years been studying the cellular causes for the death of nerve cells.

«The findings provide new insight into how cells faithfully transmit this organizational information as embryos develop, and into what goes wrong when cellular development goes awry, thereby giving rise to abnormal cell development and diseases such as cancer,» says senior study investigator Danny Reinberg, PhD, professor of biochemistry and molecular pharmacology at NYU Langone and a Howard Hughes Medical Institute investigator.

As researchers at the Max Planck Institute of Biochemistry report in the current issue of Nature, they have now decoded a new cellular mechanism for the development of aggregates.

«Our work suggests that the apparent complexity of protein networks is deceiving, and that a circuit involving a small number of proteins might control each cellular function,» said senior author Shohei Koide, PhD, professor of biochemistry & molecular biophysics at the University of Chicago.

Dr. Veenstra holds a Ph.D in biochemistry from the University of Windsor, Canada and completed his post-doctoral training in molecular and cellular biology at the Mayo Clinic / Foundation.

Scientists at the Max Planck Institute of Biochemistry in Martinsried, Germany, now discovered a new family of helper proteins that recognize labeled cellular protein waste and guide them efficiently to the lysosome for destruction and subsequent recycling into their reusable compounds.

Plant Physiology ® is an international journal devoted to physiology, biochemistry, cellular and molecular biology, genetics, biophysics, and environmental biology of plants.

Biochemistry is the study of the structure and function of cellular components, such as proteins, carbohydrates, lipids, nucleic acids, and other biomolecules.

The microbe seems to be able to replace phosphorus with arsenic in some of its basic cellular processes — suggesting the possibility of a biochemistry very different from the one we know, which could be used by organisms in past or present extreme environments on Earth, or even on other planets.

Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.

In research reported this week in the «first release» section of the journal Science, Aseem Ansari, a professor of biochemistry and genomics at UW — Madison, and colleagues showed that their «molecular prosthesis» can help cellular machinery overcome the blockade posed by the repeats in Friedreich's ataxia.

Researchers in the University of Wisconsin — Madison Department of Biochemistry have discovered that a cellular pump known to move drugs like antibiotics out of E....

«These peptides should be valuable for drug design and discovery, and for understanding fundamental aspects of cellular biology,» said John Sondek, PhD, senior author of the JBC paper and professor in UNC's departments of pharmacology and biochemistry & biophysics.

Cellular Studies (CEL): The study of animal cells involving the use of microscopy to study cell structure and studies investigating activity within cells such as enzyme pathways, cellular biochemistry, and synthesis pathways for DNA, RNA, and protein.

The SENS Research Foundation has assembled a set of narrated cellular biochemistry animations that serve as an introduction to the various distinct projects that make up the field of rejuvenation biotechnology.

Previously a distinguished professor in the University of Minnesota's Department of Biochemistry, Molecular Biology and Biophysics, Kalodimos» research into the cellular machinery relevant to cancer has led to important insights into how mutated proteins can drive the development and spread of the disease.

Dr. Miller has a background in protein biochemistry, cellular immunology, cardiac physiology, molecular immunology and molecular biology, which he developed working for over a decade in laboratories in the Medical School, Department of Chemistry, and the Molecular Biology Institute at UCLA.

Students in this program have a minimum of a baccalaureate degree in biology, biochemistry or a related field, as well as laboratory experience in at least two of the following areas: microbiology, biochemistry, genetics, or cellular biology.

Other structural biology techniques, such as cryo - electron microscopy, can not resolve cellular elements beyond an intact cell's surface, explains Julia Mahamid of the Max Planck Institute for Biochemistry, a member of the research team (Science 2016, DOI: 10.1126 / science.aad8857).

Sancar, the Sarah Graham Kenan Professor of Biochemistry and Biophysics in the UNC School of Medicine, earned the Nobel Prize in Chemistry this year for his work on mapping the cellular mechanisms that underlie DNA repair, which occurs every single minute of the day due to environmental factors.

The pre-eminent curiosity that I retain regarding health practitioners is that specialists in nutrition on occasion appear to not possess the adequate level of biochemical grounding to explain the vital processes happening at the cellular level during fasting and through manipulation of eicosanoids (fatty acids), conversely from my personal experiences, experts in biochemistry don't apply their vast knowledge of these complex physiological systems to basic fundamentals of nutrition in a sensible, practical sense.

-LSB-...] of Clinical Biochemistry and Nutrition found that the naturally occurring cellular antioxidant, alpha lipoic acid, has the ability to correct abnormal insulin signaling and resistance that are known to promote -LSB-...]

Tags for this Online Resume: Research and developmeny, scientist, oncology, molecular biology and biochemistry, cellular pharmacology, mechanisms of drug action

London, England About Blog Exploring the molecular mechanisms that underpin key biological processes, the Biochemical Journal is a leading bioscience journal publishing high - impact scientific research papers and reviews on the latest advances and new mechanistic concepts in the fields of biochemistry, cellular biosciences and molecular biology.