Sentences with phrase «of cellular differentiation»

The central problem in pattern formation is how can genetic information be translated in a reliable manner to give specific spatial patterns of cellular differentiation.

The current dogma of cellular differentiation presents a model of progressive closing of the regulatory potential of the genome during cellular differentiation.

Such marks key roles in the process of cellular differentiation, allowing cells to maintain different characteristics despite containing the same genomic material.

The authors explain in the article that NSD1 mutation has recently been linked in the scientific literature to the blocking of cellular differentiation and the promotion of oncogenesis in this type of tumor.

The research has also investigated the role of Rho - kinase inhibition on cellular - scale protein expression and stimulation of cellular differentiation of fibroblast cells.

The new paper is «by far the most complete survey of a cellular differentiation event,» says Juha Kere, a molecular geneticist at the Karolinska Institute in Stockholm, who is not affiliated with the FANTOM group.

Research Focus & Career Goals: Recent work, to which I have also contributed, and from some other laboratories has established that global regulation of cellular differentiation is the result of the coordinated interplay of dynamic changes in the organization of chromatin, epigenetic modifications, lncRNAs and transcription factors.

Unlike normal plasma cells, the malignant plasma cells look large and round with a high mitotic index (measure of the proliferation of a cell population) in early stages of cellular differentiation.